DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cp1 and si:dkey-239j18.3

DIOPT Version :9

Sequence 1:	NP_523735.2	Gene:	Cp1 / 36546	FlyBaseID:	FBgn0013770	Length:	371	Species:	Drosophila melanogaster
Sequence 2:	XP_001341714.2	Gene:	si:dkey-239j18.3 / 100001785	ZFINID:	ZDB-GENE-121214-39	Length:	336	Species:	Danio rerio

Alignment Length:	344	Identity:	168/344 - (48%)
Similarity:	233/344 - (67%)	Gaps:	15/344 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 VLLPLLALLAVAQ--AVSFADVVMEE-WHTFKLEHRKNYQDETEERFRLKIFNENKHKIAKHNQR 96
            ::..||..|:::.  |.|..|:.::: |:::|.:|.|:|.::.|...|: |:.||..||.:||..
Zfish     1 MMFALLVTLSISAVFAASSIDIQLDDHWNSWKSQHGKSYHEDVEVGRRM-IWEENLRKIEQHNFE 64

  Fly    97 FAEGKVSFKLAVNKYADLLHHEFRQLMNGFNYTLHKQLRAADESFKGVTFISPAHVTLPKSVDWR 161
            ::.|..:||:.:|::.|:.:.||||.|||:.:.       .:::.:|..|:.|:....|:.||||
Zfish    65 YSYGNHTFKMGMNQFGDMTNEEFRQAMNGYKHD-------PNQTSQGPLFMEPSFFAAPQQVDWR 122

  Fly   162 TKGAVTAVKDQGHCGSCWAFSSTGALEGQHFRKSGVLVSLSEQNLVDCSTKYGNNGCNGGLMDNA 226
            .:|.||.||||..|||||:||||||||||.|||:|.|:|:|||||||||...||.||||||||.|
Zfish   123 QRGYVTPVKDQKQCGSCWSFSSTGALEGQLFRKTGKLISMSEQNLVDCSRPQGNQGCNGGLMDQA 187

  Fly   227 FRYIKDNGGIDTEKSYPYEAIDD-SCHFNKGTVGATDRGFTDIPQGDEKKMAEAVATVGPVSVAI 290
            |:|:|:|.|:|:|:||||.|.|| .|.::.....|...||.|||.|:|..:..|||.||||||||
Zfish   188 FQYVKENKGLDSEQSYPYLARDDLPCRYDPRFNVAKITGFVDIPSGNELALMNAVAAVGPVSVAI 252

  Fly   291 DASHESFQFYSEGVYNEPQCDAQNLDHGVLVVGF---GTDESGEDYWLVKNSWGTTWGDKGFIKM 352
            ||||:|.|||..|:|.|..|.:..|||.|||||:   |.|.:|..||:|||||...|||||:|.|
Zfish   253 DASHQSLQFYQSGIYYERACSSSRLDHAVLVVGYGYQGADVAGNRYWIVKNSWSDKWGDKGYIYM 317

  Fly   353 LRNKENQCGIASASSYPLV 371
            .::|.|.||:|:.:||||:
Zfish   318 AKDKNNHCGVATKASYPLM 336

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cp1	NP_523735.2	Inhibitor_I29	59..118	CDD:214853	19/58 (33%)
Cp1	NP_523735.2	Peptidase_C1	154..370	CDD:278538	131/219 (60%)
si:dkey-239j18.3	XP_001341714.2	Inhibitor_I29	28..86	CDD:214853	19/58 (33%)
si:dkey-239j18.3	XP_001341714.2	Peptidase_C1	115..335	CDD:278538	131/219 (60%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4870
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	367	1.000	Inparanoid score	I2109
OMA	1	1.010	-	-		QHG53545
OrthoDB	1	1.010	-	-		D1275401at2759
OrthoFinder	1	1.000	-	-		FOG0000114
OrthoInspector	1	1.000	-	-		otm25207
orthoMCL	1	0.900	-	-		OOG6_100116
Panther	1	1.100	-	-	O	PTHR12411
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X64
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	11	10.880