DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rpn13 and RPN13

DIOPT Version :9

Sequence 1:	NP_001137662.1	Gene:	Rpn13 / 36545	FlyBaseID:	FBgn0033886	Length:	424	Species:	Drosophila melanogaster
Sequence 2:	NP_001031424.1	Gene:	RPN13 / 817200	AraportID:	AT2G26590	Length:	300	Species:	Arabidopsis thaliana

Alignment Length:	372	Identity:	109/372 - (29%)
Similarity:	163/372 - (43%)	Gaps:	104/372 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 LVEFRAGRMNMVGKMVHPDPRKGLVYMTQSDDGLMHFCWKDRTSGKVEDDLIVFPDDFEYKRVDQ 81
            ::|||||:|::.|..|.||.|||||.:.:.|:||:||.|.||....||||.|||||:..:::|:|
plant    14 MLEFRAGKMSLQGTRVVPDARKGLVRIARGDEGLIHFQWLDRNQNTVEDDQIVFPDEALFEKVNQ 78

  Fly    82 CKTGRVYVLKFKSSTRRMFFWMQEPKTDKDDEQCRRINELLNNPPSAHQRGGGGSNDGDLQYMLN 146
             .:.|||:|||.|..|::|||||||:.:.|.|.|..:|:.||.|
plant    79 -SSDRVYILKFNSDDRKLFFWMQEPRAEGDAELCSSVNQYLNQP--------------------- 121

  Fly   147 NMSQQQLMQLFGGVGQMGGLSSLLGQMNSRTPSSRNTSSSGGGGASALQTPENVSVPRTPSAPSK 211
                   ::..|..|....::..|..|     :..||||..|          |:.||
plant   122 -------LEFPGEEGLAAAITEELEDM-----AEDNTSSRAG----------NLVVP-------- 156

  Fly   212 SGSSRSSSNVNSQVGEGAGSSVDADAPGKNSTTSTTTASKSTGAYANPFQAYLSNLS--PEHGAG 274
                    |::|:|.:...||    .|.|.:                ..|..|:|||  |...||
plant   157 --------NLSSEVSDVTSSS----GPVKLA----------------DLQRILNNLSGGPVGIAG 193

  Fly   275 RSLNIDLSTALPGADAINQIIADPEHVKTLIVHLPESEDVDD------DRKQQIKDNITSPQFQQ 333
                 |....|...|     |..||.:..|:..||..|.:..      .|.:.|.:.:.||.|:|
plant   194 -----DQDEGLALGD-----ILKPELIMPLLEALPVQERLSSHLPEGHSRAEDILELLQSPPFRQ 248

  Fly   334 ALAQFSSALQSAQLGPVIKQFELSNEAVAAAFSGNLEDFVRALEKSL 380
            .:..|:..|::.|:.  :.||.:.    .:.:...::.|:.|||.|:
plant   249 QVDAFTYVLRTGQID--LTQFGID----PSKYKFTVDSFLEALEDSV 289

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rpn13	NP_001137662.1	PH_Rpn13	18..122	CDD:270124	53/103 (51%)
Rpn13	NP_001137662.1	RPN13_C	267..376	CDD:293158	27/116 (23%)
RPN13	NP_001031424.1	PH_Rpn13	15..118	CDD:270124	53/103 (51%)
RPN13	NP_001031424.1	RPN13_C	192..285	CDD:406854	24/108 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	95	1.000	Domainoid score	I2499
eggNOG	1	0.900	-	-		E1_KOG3037
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	131	1.000	Inparanoid score	I1876
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1479349at2759
OrthoFinder	1	1.000	-	-		FOG0003818
OrthoInspector	1	1.000	-	-		otm3038
orthoMCL	1	0.900	-	-		OOG6_102724
Panther	1	1.100	-	-	LDO	PTHR12225
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2662
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	12	11.830