Protein Alignment Rpn13 and Adrm1

DIOPT Version :10

• Sequence 1: NP_001137662.1
• Gene: Rpn13 / 36545
• FlyBaseID: FBgn0033886
• Length: 424
• Species: Drosophila melanogaster
• Sequence 2: NP_062796.2
• Gene: Adrm1 / 56436
• MGIID: 1929289
• Length: 407
• Species: Mus musculus
• Alignment Length: 427
• Identity: 181/427 - (42%)
• Similarity: 249/427 - (58%)
• Gaps: 59/427 - (13%)

  Fly     9 GSSSNSSN-LVEFRAGRMNMVGKMVHPDPRKGLVYMTQSDDGLMHFCWKDRTSGKVEDDLIVFPD 72
            ||..:|:. |||||||:|::.|..|.||.||||||:.|:||.|:||||||||||.||||||:|||
Mouse    14 GSRGSSTKYLVEFRAGKMSLKGTTVTPDKRKGLVYIQQTDDSLIHFCWKDRTSGTVEDDLIIFPD 78

  Fly    73 DFEYKRVDQCKTGRVYVLKFKSSTRRMFFWMQEPKTDKDDEQCRRINELLNNPPSAHQRGGGGSN 137
            |.|:|||.||.:|||||||||:.::|:||||||||||:|:|.||::||.|||||.....|..||:
Mouse    79 DCEFKRVPQCPSGRVYVLKFKAGSKRLFFWMQEPKTDQDEEHCRKVNECLNNPPMPGSLGASGSS 143

  Fly   138 ---------DGDLQYMLNNMSQQQLMQL-----FGGVGQMG-----GLSSLLGQMNSRTPSSRNT 183
                     :|.||.:|.|||..|||||     .||:|.:|     ||:||||  :|..|:|.::
Mouse   144 GHELSALGGEGGLQSLLGNMSHSQLMQLIGPAGLGGLGGLGALTGPGLASLLG--SSGPPASSSS 206

  Fly   184 SSSGGGGASALQTPENVSVPRTPSAPSKSGSSRSSSNVNSQVGEGAGSSVDADAPGKNSTTSTTT 248
            |||                 |:.||.....||.||:.........|.:|..:.:|..:|...|:|
Mouse   207 SSS-----------------RSQSAAVTPSSSTSSARATPAPSAPAAASATSPSPAPSSGNGTST 254

  Fly   249 ASKST-GAYANPFQAYLSNLSPEHGAGRSLNIDLSTALPGADAINQIIADPEHVKTLIVHLPESE 312
            |:..| ....:..|:.|:.::...|.|.|..:||::.|. .:.:..|:|:.:..:.|:.:||..|
Mouse   255 AASPTQPIQLSDLQSILATMNVPAGPGGSQQVDLASVLT-PEIMAPILANADVQERLLPYLPSGE 318

  Fly   313 DVDDDRKQQIKDNITSPQFQQALAQFSSALQSAQLGPVIKQFELSNEAVAAAFSGNLEDFVRALE 377
            .: .....:|::.:|||||||||..||:||.|.||||::.||.|..|||.||..|::|.|.:|::
Mouse   319 SL-PQTADEIQNTLTSPQFQQALGMFSAALASGQLGPLMCQFGLPAEAVEAANKGDVEAFAKAMQ 382

  Fly   378 KSLPPGATMGGKPSASEKKASDP-ETPTSVARDENTD 413
            .:                ..||| |..|...:||..|
Mouse   383 NN----------------AKSDPKEGDTKDKKDEEED 403

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rpn13	NP_001137662.1	PH_Rpn13	18..122	CDD:270124	73/103 (71%)
		RPN13_C	267..376	CDD:465170	42/108 (39%)
Adrm1	NP_062796.2	PH_Rpn13	24..128	CDD:270124	73/103 (71%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	196..259		21/81 (26%)
		RPN13_C	274..381	CDD:465170	42/108 (39%)
		Interaction with UCHL5. /evidence=ECO:0000250	362..407		17/58 (29%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	381..407		8/39 (21%)