DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Rpn13 and adrm1

DIOPT Version :9

Sequence 1:	NP_001137662.1	Gene:	Rpn13 / 36545	FlyBaseID:	FBgn0033886	Length:	424	Species:	Drosophila melanogaster
Sequence 2:	NP_989049.1	Gene:	adrm1 / 394646	XenbaseID:	XB-GENE-489445	Length:	404	Species:	Xenopus tropicalis

Alignment Length:	423	Identity:	183/423 - (43%)
Similarity:	244/423 - (57%)	Gaps:	66/423 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 GSSSNSSN-LVEFRAGRMNMVGKMVHPDPRKGLVYMTQSDDGLMHFCWKDRTSGKVEDDLIVFPD 72
            ||..:||. |||||||:|::.|..|.||.||||||:.|:||.|:||||||||||.||||||:|||
Frog    13 GSRGSSSKYLVEFRAGKMSLKGSTVTPDKRKGLVYIQQTDDSLIHFCWKDRTSGSVEDDLIIFPD 77

  Fly    73 DFEYKRVDQCKTGRVYVLKFKSSTRRMFFWMQEPKTDKDDEQCRRINELLNNPPSAHQRGGGGS- 136
            |.|:|||.||.||||||||||:.::|:||||||||||||:|.||::||.|||||.....||.||
Frog    78 DCEFKRVSQCTTGRVYVLKFKAGSKRLFFWMQEPKTDKDEEYCRKVNEYLNNPPMPGALGGSGSG 142

  Fly   137 --------NDGDLQYMLNNMSQQQLMQLFG--GVGQMGGLSSLLGQ-----MNSRTPSSRNTSSS 186
                    .:|.||.:|.|||..|||||.|  |:|.:|||.:|.|.     :.|..|::.::|||
Frog   143 GHELSALGGEGGLQSLLGNMSHNQLMQLIGPTGLGGLGGLGALTGPGLASLLGSGGPTTSSSSSS 207

  Fly   187 GGGGASALQTPENVSVPRTPSAPSKSGSSRSSSNVNSQVGEGAGSSVDADAPGKNSTTSTTTASK 251
            ....::|:......|..||.|||                      :..|.||   :||.:...|.
Frog   208 SRSQSAAVTPSSTTSSTRTTSAP----------------------AAPAAAP---ATTPSPAVSS 247

  Fly   252 STGAYA-----NPFQAYLSNLS--------PEHGAGRSLNIDLSTALPGADAINQIIADPEHVKT 303
            :.||.|     .|.|  ||:|.        |..|.| ...:||::.|. .:.:..|:|:.|..:.
Frog   248 NDGASAATSPTQPIQ--LSDLQNILATMNVPATGEG-GQQVDLASVLT-PEIMAPILANAEVQER 308

  Fly   304 LIVHLPESEDVDDDRKQQIKDNITSPQFQQALAQFSSALQSAQLGPVIKQFELSNEAVAAAFSGN 368
            |:.:||..|.: .....:|::.:|||||||||:.||:||.|.||||::.||.|..:||.||..|:
Frog   309 LMPYLPSGESL-PQTADEIQNTLTSPQFQQALSMFSAALASGQLGPLMSQFGLPADAVDAANKGD 372

  Fly   369 LEDFVRALEKSLPPGATMGGKPSASEKKASDPE 401
            :|.|.:|::      .|...|...|.:|..:.|
Frog   373 IEAFAKAMQ------TTSSQKERESSEKKEEEE 399

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rpn13	NP_001137662.1	PH_Rpn13	18..122	CDD:270124	75/103 (73%)
Rpn13	NP_001137662.1	RPN13_C	267..376	CDD:293158	43/116 (37%)
adrm1	NP_989049.1	PH_Rpn13	23..127	CDD:270124	75/103 (73%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	195..258		21/87 (24%)
		RPN13_C	273..380	CDD:374621	42/109 (39%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	377..404		6/29 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	136	1.000	Domainoid score	I4904
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	293	1.000	Inparanoid score	I2720
OMA	1	1.010	-	-		QHG59102
OrthoDB	1	1.010	-	-		D1479349at2759
OrthoFinder	1	1.000	-	-		FOG0003818
OrthoInspector	1	1.000	-	-		oto104277
Panther	1	1.100	-	-	LDO	PTHR12225
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1994
SonicParanoid	1	1.000	-	-		X2662
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	11	11.110