DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rpn13 and rpn1301

DIOPT Version :9

Sequence 1:	NP_001137662.1	Gene:	Rpn13 / 36545	FlyBaseID:	FBgn0033886	Length:	424	Species:	Drosophila melanogaster
Sequence 2:	NP_596747.1	Gene:	rpn1301 / 2540980	PomBaseID:	SPBC342.04	Length:	291	Species:	Schizosaccharomyces pombe

Alignment Length:	366	Identity:	84/366 - (22%)
Similarity:	147/366 - (40%)	Gaps:	88/366 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 NLVEFRAGRMNMV--GKMVHPDPRKGLVYMTQSDDGLMHFCWKDRTS-GKVEDDLIVFPDDFEYK 77
            :|:.|:||::..|  .|::..||.||.:.|.:...||:||.|..|.. ...|||:|||..:..::
pombe     2 SLITFKAGKLRRVPGTKLLRADPEKGYIVMNRDAYGLIHFQWAKRNDLENPEDDIIVFSSECTFE 66

  Fly    78 RVDQCKTGRVYVLKFKSSTRRMFFWMQEPKTDKDDEQCRRINELLNNPPSAHQRGGGGSNDGDLQ 142
            :|.:|.|||.|:||:.||...:|:||||...|.|.....|||..:.:
pombe    67 KVTECTTGRAYMLKYPSSAHSLFYWMQEASDDNDTSYAERINSYIKD------------------ 113

  Fly   143 YMLNNMSQQQLMQLFGGVGQMGGLSSLLGQMNSRTPSSRNTSSSGGGGASALQTPENVSVPRTPS 207
                    |.|:.                      |:..:.::     .|.:...:.|......:
pombe   114 --------QDLLD----------------------PARSDVAT-----VSDMMEVDTVEQSEPIA 143

  Fly   208 APSKSGSSRSSSNVNSQVGEGAGSSVDADAPGKNSTTSTTTASKSTGAYANPFQAYLSNLSPEHG 272
            .|::      ||..:|::|          ||..:...|:...           :..|:.:|.:.|
pombe   144 QPTE------SSKESSEIG----------APNSDEINSSEAV-----------RNLLATISAQAG 181

  Fly   273 AGRSLNIDLSTALPGADAINQIIADPEHVKTLIVHLPESEDVDDDRKQQIKDNITSPQFQQALAQ 337
            .|.| .:||...|..:: :..::.....:..|:.::|..   ..:..:.:...::|||:.|||..
pombe   182 FGGS-TVDLCEILKPSN-LTDLLCQEGVIDRLMPYMPPD---TPNNLEGVLAIVSSPQYAQALRS 241

  Fly   338 FSSALQSAQLGPVIKQFELSNEAVAAAFSGNLEDFVRALEK 378
            ||.||.|.....:|....||.:..|....|....|::|:.:
pombe   242 FSQALNSPGGVNIISALGLSLDESANPNEGGALQFLKAIAR 282

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rpn13	NP_001137662.1	PH_Rpn13	18..122	CDD:270124	42/106 (40%)
Rpn13	NP_001137662.1	RPN13_C	267..376	CDD:293158	26/108 (24%)
rpn1301	NP_596747.1	PH_Rpn13	4..111	CDD:270124	42/106 (40%)
rpn1301	NP_596747.1	RPN13_C	177..280	CDD:293158	26/107 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3037
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003818
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_102724
Panther	1	1.100	-	-	LDO	PTHR12225
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1994
SonicParanoid	1	1.000	-	-		X2662
TreeFam	1	0.960	-	-
	9	8.800