Protein Alignment Rpn13 and ADRM1

DIOPT Version :9

• Sequence 1: NP_001137662.1
• Gene: Rpn13 / 36545
• FlyBaseID: FBgn0033886
• Length: 424
• Species: Drosophila melanogaster
• Sequence 2: XP_024307582.1
• Gene: ADRM1 / 11047
• HGNCID: 15759
• Length: 470
• Species: Homo sapiens
• Alignment Length: 487
• Identity: 176/487 - (36%)
• Similarity: 245/487 - (50%)
• Gaps: 119/487 - (24%)

  Fly    11 SSNSSN--LVEFRAGRMNMVGKMVHPDPRKGLVYMTQSDDGLMHFCWKDRTSGKVEDDLIVFPDD 73
            |..:||  |||||||:|::.|..|.||.||||||:.|:||.|:||||||||||.||||||:||||
Human    15 SRGASNKYLVEFRAGKMSLKGTTVTPDKRKGLVYIQQTDDSLIHFCWKDRTSGNVEDDLIIFPDD 79

  Fly    74 FEYKRVDQCKTGRVYVLKFKSSTRRMFFWMQEPKTDKDDEQCRRINELLNNPPSAHQRGGGGSN- 137
            .|:|||.||.:|||||||||:.::|:||||||||||:|:|.||::||.|||||.....|..||:
Human    80 CEFKRVPQCPSGRVYVLKFKAGSKRLFFWMQEPKTDQDEEHCRKVNEYLNNPPMPGALGASGSSG 144

  Fly   138 --------DGDLQYMLNNMSQQQLMQL-----FGGVGQMG-----GLSSLLGQMNSRTPSSRNTS 184
                    :|.||.:|.|||..|||||     .||:|.:|     ||:||||  :|..|.|.::|
Human   145 HELSALGGEGGLQSLLGNMSHSQLMQLIGPAGLGGLGGLGALTGPGLASLLG--SSGPPGSSSSS 207

  Fly   185 SSGGGGASALQTPENVSVPRTPSAPSKSGSSRSSSNVNSQVGEGAGSSVDADAPGKNSTTSTTTA 249
            ||....|:...:....|...||:..:.:.:|.:|.:.....|.||                :|.|
Human   208 SSRSQSAAVTPSSTTSSTRATPAPSAPAAASATSPSPAPSSGNGA----------------STAA 256

  Fly   250 SKSTGAYANPFQAYLSNLSPEHGAGRSLNIDLSTALPGADAINQIIADPEHVKTLIVHLPESEDV 314
            |.:.....:..|:.|:.::...|......:||::.|. .:.:..|:|:.:..:.|:.:||..|.:
Human   257 SPTQPIQLSDLQSILATMNVPAGPAGGQQVDLASVLT-PEIMAPILANADVQERLLPYLPSGESL 320

  Fly   315 DDDRKQQIKDNITSPQFQ----------------------------------------------- 332
             .....:|::.:||||||
Human   321 -PQTADEIQNTLTSPQFQQVEAGPRVSSTVCSGSGQGGGGGPAPPSPWPVLHVPDPQSWQLSSVA 384

  Fly   333 ----------------QALAQFSSALQSAQLGPVIKQFELSNEAVAAAFSGNLEDFVRALEKSLP 381
                            |||..||:||.|.||||::.||.|..|||.||..|::|.|.:|::.:..
Human   385 LGCSPGWSSALAWLFLQALGMFSAALASGQLGPLMCQFGLPAEAVEAANKGDVEAFAKAMQNNAK 449

  Fly   382 PGATMGGKPSASEKKASDPETPTSVARDENTD 413
            |           |:|..|    |...:||..|
Human   450 P-----------EQKEGD----TKDKKDEEED 466

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rpn13	NP_001137662.1	PH_Rpn13	18..122	CDD:270124	73/103 (71%)
		RPN13_C	267..376	CDD:293158	40/171 (23%)
ADRM1	XP_024307582.1	PH_Rpn13	24..128	CDD:270124	73/103 (71%)
		RPN13_C	274..444	CDD:318700	40/171 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165148052
Domainoid	1	1.000	134	1.000	Domainoid score	I5037
eggNOG	1	0.900	-	-		E1_KOG3037
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	283	1.000	Inparanoid score	I2879
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG59102
OrthoDB	1	1.010	-	-		D1479349at2759
OrthoFinder	1	1.000	-	-		FOG0003818
OrthoInspector	1	1.000	-	-		oto90475
orthoMCL	1	0.900	-	-		OOG6_102724
Panther	1	1.100	-	-	LDO	PTHR12225
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1994
SonicParanoid	1	1.000	-	-		X2662
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	15	14.800