Protein Alignment AGO1 and AGO5

DIOPT Version :10

• Sequence 1: NP_725341.1
• Gene: AGO1 / 36544
• FlyBaseID: FBgn0262739
• Length: 984
• Species: Drosophila melanogaster
• Sequence 2: NP_850110.1
• Gene: AGO5 / 817334
• AraportID: AT2G27880
• Length: 997
• Species: Arabidopsis thaliana
• Alignment Length: 979
• Identity: 378/979 - (38%)
• Similarity: 550/979 - (56%)
• Gaps: 70/979 - (7%)

  Fly    37 GKVYESQWTPSPTRPQSPSQAQTSFDTLTSPPAPGSSVNPTAVTSPSAQNVAAGGATVAGAAAT- 100
            |.|...:.|...|..|.|..:..|     .....|:..:||...:.|::.|:...::...:..|
plant    56 GNVGRGENTGDLTATQVPVASAVS-----GGRGRGNIGDPTFSVASSSKTVSVASSSKEESKNTE 115

  Fly   101 AAQVASALGATTGSVTPAIATATPATQPDMPVFTCPRRPNLGREGRPIVLRANHFQVTMPRGYVH 165
            .::..|.|..|:....|.:.:..||:.   ...|.|.||..|..|:.:::|||||.|.:....::
plant   116 VSETMSNLQITSTETKPEMTSLPPASS---KAVTFPVRPGRGTLGKKVMVRANHFLVQVADRDLY 177

  Fly   166 HYDINIQPDKCPRKVNREIIETMVHAY-SKIFGVLKPVFDGRNNLYTRDPLPIGNERLELEVTLP 229
            |||::|.|:...:.|||.:::.:|..| ....|...|.:|||.:|||..|||..::  |..|.|.
plant   178 HYDVSINPEVISKTVNRNVMKLLVKNYKDSHLGGKSPAYDGRKSLYTAGPLPFDSK--EFVVNLA 240

  Fly   230 ------GEGKDRIFRVTIKWQAQVSLFNLEEALEGRTRQIPYDAILALDVVMRHLPSMTYTPVGR 288
                  ..||||.|:|.:|......|:.|::.|:.:.|:.|||.|..||||:|..||..|..|||
plant   241 EKRADGSSGKDRPFKVAVKNVTSTDLYQLQQFLDRKQREAPYDTIQVLDVVLRDKPSNDYVSVGR 305

  Fly   289 SFFSSPEGY-----YHPLGGGREVWFGFHQSVRPSQWKMMLNIDVSATAFYKAQPVIDFMCEVLD 348
            |||.:..|.     ...||.|.|.|.|:.||:|.:|..:.|||||||.:||:...|.||:.:.|:
plant   306 SFFHTSLGKDARDGRGELGDGIEYWRGYFQSLRLTQMGLSLNIDVSARSFYEPIVVTDFISKFLN 370

  Fly   349 IRDINEQRKPLTDSQRVKFTKEIKGLKIEITHCGQMRRKYRVCNVTRRPAQMQSFPLQLENGQTV 413
            |||:|   :||.||.|:|..|.::.||:::.|... .:..::..::..|.:...|.|:.::
plant   371 IRDLN---RPLRDSDRLKVKKVLRTLKVKLLHWNG-TKSAKISGISSLPIRELRFTLEDKS---- 427

  Fly   414 ECTVAKYFLDKYRMKLRYPHLPCLQVGQEHKHTYLPLEVCNIVAGQRCIKKLTDMQTSTMIKATA 478
            |.||.:||.:||..:::|..||.:|.|.:.:..|||:|:|.|..|||..|:|.:.|.:.::|||.
plant   428 EKTVVQYFAEKYNYRVKYQALPAIQTGSDTRPVYLPMELCQIDEGQRYTKRLNEKQVTALLKATC 492

  Fly   479 RSAPDREREINNLVKRADFNNDSYVQEFGLTISNSMMEVRGRVLPPPKLQYGGRVSTGLTGQQLF 543
            :..||||..|.|||.:.::|:| ..:|||::::..:..:..||||||.|:|
plant   493 QRPPDRENSIKNLVVKNNYNDD-LSKEFGMSVTTQLASIEARVLPPPMLKY-------------- 542

  Fly   544 PPQNKVSLASPNQGVWDMRGKQFFTGVEIRIWAIACFAPQRTVREDALRNFTQQLQKISNDAGMP 608
            ....|..:.:|..|.|:|..|:...|.::..|....|:.:  :.....:.|.:||..:....||.
plant   543 HDSGKEKMVNPRLGQWNMIDKKMVNGAKVTSWTCVSFSTR--IDRGLPQEFCKQLIGMCVSKGME 605

  Fly   609 IIGQPCFCKYATGPDQVEPMFRYLKITFPGLQLVVVVLPGKTPVYAEVKRVGDTVLGMATQCVQA 673
            ...||.....:..|:.:|.....:....|||||::|:||..|..|.::||:.:|.||:.:||.|.
plant   606 FKPQPAIPFISCPPEHIEEALLDIHKRAPGLQLLIVILPDVTGSYGKIKRICETELGIVSQCCQP 670

  Fly   674 KNVNKTSPQTLSNLCLKINVKLGGINSILVPSIR---PKVFNEPVIFLGADVTHPPAGDNKKPSI 735
            :.|||.:.|.:.|:.||||||.||.|::|..:||   |.:.:.|.|.:|||||||..|::..|||
plant   671 RQVNKLNKQYMENVALKINVKTGGRNTVLNDAIRRNIPLITDRPTIIMGADVTHPQPGEDSSPSI 735

  Fly   736 AAVVGSMD-AHPSRYAATVRVQQHRQEIIQEL-------------SSMVRELLIMFYKSTGGYKP 786
            ||||.||| ...::|...|..|.||:||||:|             |.::||..|.|.::||.. |
plant   736 AAVVASMDWPEINKYRGLVSAQAHREEIIQDLYKLVQDPQRGLVHSGLIREHFIAFRRATGQI-P 799

  Fly   787 HRIILYRDGVSEGQFPHVLQHELTAIREACIKLEPEYRPGITFIVVQKRHHTRLFCAE--KKEQS 849
            .|||.||||||||||..||.||:||||:||..|:..|.|.:||::||||||||||..:  .::.:
plant   800 QRIIFYRDGVSEGQFSQVLLHEMTAIRKACNSLQENYVPRVTFVIVQKRHHTRLFPEQHGNRDMT 864

  Fly   850 GKSGNIPAGTTVDVGITHPTEFDFYLCSHQGIQGTSRPSHYHVLWDDNHFDSDELQCLTYQLCHT 914
            .|||||..||.||..|.||.||||||.||.||||||||:|||||.|:|.|.:|:||.||..||:|
plant   865 DKSGNIQPGTVVDTKICHPNEFDFYLNSHAGIQGTSRPAHYHVLLDENGFTADQLQMLTNNLCYT 929

  Fly   915 YVRCTRSVSIPAPAYYAHLVAFRARYHLVEKEHDSGEGSHQSGCSEDRTPGAMARAITVHADTKK 979
            |.|||:||||..|||||||.||||||:: |.|...| ||.:|..|.......:::...:..:.|:
plant   930 YARCTKSVSIVPPAYYAHLAAFRARYYM-ESEMSDG-GSSRSRSSTTGVGQVISQLPAIKDNVKE 992

  Fly   980 VMYF 983
            ||::
plant   993 VMFY 996

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AGO1	NP_725341.1	ArgoN	146..275	CDD:465134	48/135 (36%)
		ArgoL1	285..335	CDD:462567	25/54 (46%)
		PAZ_argonaute_like	336..456	CDD:239212	38/119 (32%)
		Piwi_ago-like	502..942	CDD:240015	206/458 (45%)
AGO5	NP_850110.1	PLN03202	131..997	CDD:215631	362/899 (40%)