DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment AGO1 and C03D6.1

DIOPT Version :9

Sequence 1:	NP_001246314.1	Gene:	AGO1 / 36544	FlyBaseID:	FBgn0262739	Length:	984	Species:	Drosophila melanogaster
Sequence 2:	NP_492571.1	Gene:	C03D6.1 / 182158	WormBaseID:	WBGene00007275	Length:	262	Species:	Caenorhabditis elegans

Alignment Length:	147	Identity:	37/147 - (25%)
Similarity:	55/147 - (37%)	Gaps:	42/147 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   698 INSILVPSIRPKVFNEP--VIFLGADVTHPPAGDN-------KKPSIAAVVGSMDAHPSRYAATV 753
            ||...|....|.|:|.|  |:|.....:.|   |:       :|.:|..|..::....:|:
Worm    38 INHGTVDPSTPGVYNNPSTVVFTFNGTSCP---DHFTEYFHFQKATIPHVDPALIRRVTRW---- 95

  Fly   754 RVQQHRQEIIQELSSMVRELLIMFYKSTGGYKPHRIILYRDGVSEGQFPHVLQHELTAIR-EACI 817
                    ||::..|. ||:|           |..||:.||.|.:.....|...|.||.: |...
Worm    96 --------IIEDFRSH-REVL-----------PDFIIVLRDQVRDDLQSTVEHQEFTAFKEEIST 140

  Fly   818 KLE-----PEYRPGITF 829
            .:|     ||:.|...|
Worm   141 YIETASNLPEWNPRFAF 157

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AGO1	NP_001246314.1	ArgoN	146..275	CDD:406799
		ArgoL1	285..335	CDD:400854
		PAZ_argonaute_like	336..456	CDD:239212
		Piwi_ago-like	502..942	CDD:240015	37/147 (25%)
C03D6.1	NP_492571.1	Piwi-like	<27..>157	CDD:294420	36/145 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1041
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900