DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DJ-1alpha and Park7

DIOPT Version :9

Sequence 1:	NP_610916.1	Gene:	DJ-1alpha / 36543	FlyBaseID:	FBgn0033885	Length:	217	Species:	Drosophila melanogaster
Sequence 2:	NP_065594.2	Gene:	Park7 / 57320	MGIID:	2135637	Length:	189	Species:	Mus musculus

Alignment Length:	185	Identity:	103/185 - (55%)
Similarity:	130/185 - (70%)	Gaps:	4/185 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 AKNALIILAPGAEEMEFTISADVLRRGKILVTVAGLHDCEPVKCSRSVVIVPDTSLEEAVTRGDY 94
            :|.||:|||.||||||..|..||:||..|.||||||...:||:|||.|:|.||||||:|.|:|.|
Mouse     3 SKRALVILAKGAEEMETVIPVDVMRRAGIKVTVAGLAGKDPVQCSRDVMICPDTSLEDAKTQGPY 67

  Fly    95 DVVVLPGGLAGNKALMNSSAVGDVLRCQESKGGLIAAICAAPTALAKHGIGKGKSITSHPDMKPQ 159
            ||||||||..|.:.|..|..|.::|:.|||:.||||||||.||||..|.:|.|..:|:||..|.:
Mouse    68 DVVVLPGGNLGAQNLSESPMVKEILKEQESRKGLIAAICAGPTALLAHEVGFGCKVTTHPLAKDK 132

  Fly   160 LK--ELYCYIDDKTVVQDGNIITSRGPGTTFDFALKITEQLVGAEVAKEVAKAML 212
            :.  ..|.|.:.: |.:||.|:|||||||:|:|||.|.|.|||.::|.:| ||.|
Mouse   133 MMNGSHYSYSESR-VEKDGLILTSRGPGTSFEFALAIVEALVGKDMANQV-KAPL 185

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DJ-1alpha	NP_610916.1	ThiJ	33..210	CDD:333423	99/178 (56%)
Park7	NP_065594.2	not_thiJ	5..184	CDD:213612	100/180 (56%)
Park7	NP_065594.2	GATase1_DJ-1	6..172	CDD:153229	94/166 (57%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167837971
Domainoid	1	1.000	171	1.000	Domainoid score	I3729
eggNOG	1	0.900	-	-		E1_COG0693
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H38295
Inparanoid	1	1.050	181	1.000	Inparanoid score	I3969
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54253
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002774
OrthoInspector	1	1.000	-	-		otm44207
orthoMCL	1	0.900	-	-		OOG6_101257
Panther	1	1.100	-	-	O	PTHR48094
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1763
SonicParanoid	1	1.000	-	-		X2164
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.790