DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DJ-1alpha and djr-1.2

DIOPT Version :9

Sequence 1:	NP_610916.1	Gene:	DJ-1alpha / 36543	FlyBaseID:	FBgn0033885	Length:	217	Species:	Drosophila melanogaster
Sequence 2:	NP_504132.1	Gene:	djr-1.2 / 183625	WormBaseID:	WBGene00016789	Length:	186	Species:	Caenorhabditis elegans

Alignment Length:	183	Identity:	80/183 - (43%)
Similarity:	112/183 - (61%)	Gaps:	7/183 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 KNALIILAP-GAEEMEFTISADVLRRGKILVTVAGLHDCEPVKCSRSVVIVPDTSLEEAVTRGDY 94
            |:|||:|.| .|||:|..::.|||.||.:.|..|| ...|||||::...||||.:|:: |....:
Worm     5 KSALILLPPEDAEEIEVIVTGDVLVRGGLQVLYAG-SSTEPVKCAKGARIVPDVALKD-VKNKTF 67

  Fly    95 DVVVLPGGLAGNKALMNSSAVGDVLRCQESKGGLIAAICAAPTALAKHGIGKGKSITSHPDMKPQ 159
            |::::||| .|...|.....:|::|:.|...||||.||||.||.|..||| ..:.:|.|..:|.:
Worm    68 DIIIIPGG-PGCSKLAECPVIGELLKTQVKSGGLIGAICAGPTVLLAHGI-VAERVTCHYTVKDK 130

  Fly   160 LKE-LYCYIDDKTVVQDGNIITSRGPGTTFDFALKITEQLVGAEVAKEVAKAM 211
            :.| .|.|:||..|:.| .:|||:||||.|:|||||.|.|.|.|....:.|.:
Worm   131 MTEGGYKYLDDNVVISD-RVITSKGPGTAFEFALKIVETLEGPEKTNSLLKPL 182

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DJ-1alpha	NP_610916.1	ThiJ	33..210	CDD:333423	78/178 (44%)
djr-1.2	NP_504132.1	DJ-1_PfpI	5..167	CDD:280192	75/166 (45%)
djr-1.2	NP_504132.1	not_thiJ	6..181	CDD:213612	78/179 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160159836
Domainoid	1	1.000	172	1.000	Domainoid score	I2233
eggNOG	1	0.900	-	-		E1_COG0693
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H38295
Inparanoid	1	1.050	182	1.000	Inparanoid score	I2638
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54253
OrthoDB	1	1.010	-	-		D1165707at2759
OrthoFinder	1	1.000	-	-		FOG0002774
OrthoInspector	1	1.000	-	-		mtm4745
orthoMCL	1	0.900	-	-		OOG6_101257
Panther	1	1.100	-	-	O	PTHR48094
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2164
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.770