DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment shot and UTRN

DIOPT Version :10

Sequence 1:NP_725339.1 Gene:shot / 36542 FlyBaseID:FBgn0013733 Length:8805 Species:Drosophila melanogaster
Sequence 2:NP_009055.2 Gene:UTRN / 7402 HGNCID:12635 Length:3433 Species:Homo sapiens


Alignment Length:3702 Identity:724/3702 - (19%)
Similarity:1368/3702 - (36%) Gaps:953/3702 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly  4832 FGLLEAITFNLYNPTNGCLVDPFQMHPDIIRRRKFTLAEAIGSGLVDPSSTVVRDPSTGVIVPLT 4896
            :|..||...|..|..:..:......|.|:   :|.|..:.|.:.........:.|..|.      
Human     4 YGEHEASPDNGQNEFSDIIKSRSDEHNDV---QKKTFTKWINARFSKSGKPPINDMFTD------ 59

  Fly  4897 AAISSG--LIDATEGRLTDANEPK----------------------NNIDLVKA----------- 4926
              :..|  |:|..|| ||..:.||                      ||::||..           
Human    60 --LKDGRKLLDLLEG-LTGTSLPKERGSTRVHALNNVNRVLQVLHQNNVELVNIGGTDIVDGNHK 121

  Fly  4927 ------------------------------AEKGLLLPAEQRQAVFEKFNMCEENVN-------- 4953
                                          :||.||....|....:.:.|:.....:        
Human   122 LTLGLLWSIILHWQVKDVMKDVMSDLQQTNSEKILLSWVRQTTRPYSQVNVLNFTTSWTDGLAFN 186

  Fly  4954 --------DLLKWVTTVEQKISSVGGPREKIDELRNQINALKQIKDEIESQQRP----VATCLEQ 5006
                    ||..|...|  |:|.:........:.:..:...|.:..|..:.|.|    :...|..
Human   187 AVLHRHKPDLFSWDKVV--KMSPIERLEHAFSKAQTYLGIEKLLDPEDVAVQLPDKKSIIMYLTS 249

  Fly  5007 IRQIVLTGGDVLSAPEVTTLENSGRELRSRVDRVNDRTVRLLRRLEAGRDELTKLRSELDVFSD- 5070
            :.:::.....:.:..||.||....:: ....:.:|.::.......|:.|.|.....:|:|:..| 
Human   250 LFEVLPQQVTIDAIREVETLPRKYKK-ECEEEAINIQSTAPEEEHESPRAETPSTVTEVDMDLDS 313

  Fly  5071 ----------WLQVARRTLEDKERSLSDLTRLPSQADSVREFVSDVIGHQADLRFITMAAQKFVD 5125
                      ||..|..|.::::....|:..:..|..:...|:.::..||:.:..:..|..:.:.
Human   314 YQIALEEVLTWLLSAEDTFQEQDDISDDVEEVKDQFATHEAFMMELTAHQSSVGSVLQAGNQLIT 378

  Fly  5126 ESKEFLAILNDFRTSLPERLPHVEPLSSAESPIRQEVSLVSAQYKDLLNRVNALQDRVSGLGGRQ 5190
            :     ..|:|                ..|..|:::::|::|:::.|  ||.:: ||.|.|....
Human   379 Q-----GTLSD----------------EEEFEIQEQMTLLNARWEAL--RVESM-DRQSRLHDVL 419

  Fly  5191 REYQ-DALDKANEWLRSVHPRVSRIISEPIAGDPKGVQDQMNEAKALHNELLSSGRLVDNAQQAL 5254
            .|.| ..|.:.:.||.....|:.::.:.|:..|.|.:|..:.|.|:|.::|        .|:|..
Human   420 MELQKKQLQQLSAWLTLTEERIQKMETCPLDDDVKSLQKLLEEHKSLQSDL--------EAEQVK 476

  Fly  5255 DNLLRSLGGQLSPMEINQLELPIADLKNNYQQLLDNLGEHCKTLDKTLVQSQGV----QDALDS- 5314
            .|   ||...:..::.|..|...|.|::..|:|.:.....|:..::...:.|.:    |:.|:. 
Human   477 VN---SLTHMVVIVDENSGESATAILEDQLQKLGERWTAVCRWTEERWNRLQEINILWQELLEEQ 538

  Fly  5315 --LVGWVNQAEDKFKMNLRPASLIKER--LQEQIREHKVLLADLQSHQASIDSVQVSAKHLLASA 5375
              |..|:.:.|:  .:|....|..|::  |...:|...:|..|::..:.::|.:....:.:....
Human   539 CLLKAWLTEKEE--ALNKVQTSNFKDQKELSVSVRRLAILKEDMEMKRQTLDQLSEIGQDVGQLL 601

  Fly  5376 SNARIAKKVESNLNDVTVKFEKLYEKANKRGEFLDDVYNRLSRYLDEISTVEQRMASLQEALDSR 5440
            .|::.:||:.|:..::|.:::.|.::       |:|..|::::.:.::...:.....|.|.:..|
Human   602 DNSKASKKINSDSEELTQRWDSLVQR-------LEDSSNQVTQAVAKLGMSQIPQKDLLETVRVR 659

  Fly  5441 ETSLL--STEEL-------ARRMN---ELSRDKDQLAPQFEDCVRSGKDLISLRDV------TDT 5487
            |.::.  |.:||       .|:::   |..:..|.::.:..:.:...|..|...::      .||
Human   660 EQAITKKSKQELPPPPPPKKRQIHVDIEAKKKFDAISAELLNWILKWKTAIQTTEIKEYMKMQDT 724

  Fly  5488 GVLRDRIKALESQWRNINISIDERAKLSKQKAEQQLAYEGLKDQVLSWLASTEARVNGLPPVAID 5552
            ..::.::||||.:.|. .|...:....:.|...:|:..|||         .||...|.|..|:  
Human   725 SEMKKKLKALEKEQRE-RIPRADELNQTGQILVEQMGKEGL---------PTEEIKNVLEKVS-- 777

  Fly  5553 LDRIKQQHDELKPICKDYRDYAPTIDKINDIGAQYDALIRPESPARKRSTYSPIKRTSPLRRMSG 5617
                    .|.|.:.:...|....|....||.|.:..|...|...:.:..:  :|.||    :|.
Human   778 --------SEWKNVSQHLEDLERKIQLQEDINAYFKQLDELEKVIKTKEEW--VKHTS----ISE 828

  Fly  5618 DARSPSPTKGGILSPLSTGSSGFGSR----RSSQDGFQLSELSP--VQQQLSEINNRYGLIGVRL 5676
            .:|...|:.........|...|...:    |:|.........:|  ||:.......||..:...:
Human   829 SSRQSLPSLKDSCQRELTNLLGLHPKIEMARASCSALMSQPSAPDFVQRGFDSFLGRYQAVQEAV 893

  Fly  5677 NDRQHELDNLNEELRKQ-----YENLKGLAQFLERIQR--QLPKESVSNKDEAERCIKQARKILE 5734
            .|||..|:|   ||:.|     .|.||.|...|...:.  |:....:::..:.|:.: |.:|.|:
Human   894 EDRQQHLEN---ELKGQPGHAYLETLKTLKDVLNDSENKAQVSLNVLNDLAKVEKAL-QEKKTLD 954

  Fly  5735 DMYEKQ-----SLLDTTKAQVKDILRRKSDVPGAEQL-RQENDSIQEKWKNLNDICKNRIAFSEK 5793
            ::.|.|     .|.:.|||..|::      .|..|:| :||.|.:|.||..|..:....:...|:
Human   955 EILENQKPALHKLAEETKALEKNV------HPDVEKLYKQEFDDVQGKWNKLKVLVSKDLHLLEE 1013

  Fly  5794 ----LRDFLDTHGNLKSWLDSKERMLTVLGPISSDPRMVQSQVQQVQVLREEFRTQQPQLKHFQE 5854
                ||.|......::.|:|..:..|........|...:|.|:.|......|..|.:..||:.:|
Human  1014 IALTLRAFEADSTVIEKWMDGVKDFLMKQQAAQGDDAGLQRQLDQCSAFVNEIETIESSLKNMKE 1078

  Fly  5855 LGHDVVDHLAGTPDAQAVEIKLKDILGKWDDLVGKLDDRANSLGGAADSSKEFDAAVNRLREALQ 5919
            :                                     ..|...|.....|.:  ...||     
Human  1079 I-------------------------------------ETNLRSGPVAGIKTW--VQTRL----- 1099

  Fly  5920 NISDNLDTLPTDGDHQENLRKIENLERQLEGQRPLLADVEQSAATLCNILGDPASRADVNSRVAA 5984
                        ||:|..|   |.|.:::..|:..|::.::.||.|...|      |::...:..
Human  1100 ------------GDYQTQL---EKLSKEIATQKSRLSESQEKAANLKKDL------AEMQEWMTQ 1143

  Fly  5985 LEKQYLALQKKLDTKKAETEASLRDGRHFAENCSKTLGWLGGELSNLTDRLLVSAHKPTLQHQID 6049
            .|::|  |::..:.|..|                        ||.:..:. :..|.:..||.:: 
Human  1144 AEEEY--LERDFEYKSPE------------------------ELESAVEE-MKRAKEDVLQKEV- 1180

  Fly  6050 THEPIYREVMAREHEVIMLINK----GKDLTDRQQDRGVKRDLDRIQQQWEKLRREAVDRHT--R 6108
                   .|...:..:.:|..|    |::||..     :...|:..|....::|.:.   ||  .
Human  1181 -------RVKILKDNIKLLAAKVPSGGQELTSE-----LNVVLENYQLLCNRIRGKC---HTLEE 1230

  Fly  6109 LQTCMEHCKKYSQTSETFLAWLRTAEDKL--ADLTP---GVLSKA--KLETRLRDLQTFRSEVWK 6166
            :.:|......|.....|   ||.|.|:::  .::.|   ..:::|  .||:.||.....|:::  
Human  1231 VWSCWIELLHYLDLETT---WLNTLEERMKSTEVLPEKTDAVNEALESLESVLRHPADNRTQI-- 1290

  Fly  6167 HSGEFENTKGLGETFLSSCDIDKEPIKAELQDIRDRWERLNNDLIARAHEIENCSRRLDDFNDEL 6231
                    :.||:|.:....:| :.|..:|:....|:|.|::...::...:|...:.|.:.:..|
Human  1291 --------RELGQTLIDGGILD-DIISEKLEAFNSRYEDLSHLAESKQISLEKQLQVLRETDQML 1346

  Fly  6232 RNLDHSLGRCEDRLAAHDALGGAAKDPKLLERVKAIREELTNLSKPLQSLKALAKDISAEARAAG 6296
            :.|..|||..:.:|..:           |.:|:.|.:     :.:..|.::|   :|||.     
Human  1347 QVLQESLGELDKQLTTY-----------LTDRIDAFQ-----VPQEAQKIQA---EISAH----- 1387

  Fly  6297 GDADHLTSEVDGLADRMSELQGRLDDRCGELQSAATAVSQFNEQMKSLGIDLNDLETEIEKLSPP 6361
                .||.|         ||  |.:.|...|.|..:..::...||..|...|.::.|:.:....|
Human  1388 ----ELTLE---------EL--RRNMRSQPLTSPESRTARGGSQMDVLQRKLREVSTKFQLFQKP 1437

  Fly  6362 GREIKIVQVQIDDVGKIQTKLDRLVGRLEDAERAADVLVDAGFAADTTQTREQISTLRKTLGRLD 6426
            .                     ....|:.|.:|..|     |..|:                   
Human  1438 A---------------------NFEQRMLDCKRVLD-----GVKAE------------------- 1457

  Fly  6427 NRVRDHEDNLHSTLKALREFYDHQSQTLDDIQDVSDEFKRMKPVGSELDQIRRQQEDFRNFRERK 6491
                     ||                :.|::||..:.     :.:.||:..:.   ::...|.|
Human  1458 ---------LH----------------VLDVKDVDPDV-----IQTHLDKCMKL---YKTLSEVK 1489

  Fly  6492 VEPLAINVDKVNVAGRDLVRSAGSGVSTTAIEKDLEKLNDRWNDLKERMNERDRRLDVALLQSGK 6556
            :|     |:.|...||.:|:...:. :...:::.|..|...:|||..::.|..:.|:.|...:.|
Human  1490 LE-----VETVIKTGRHIVQKQQTD-NPKGMDEQLTSLKVLYNDLGAQVTEGKQDLERASQLARK 1548

  Fly  6557 FQEALAGLSKWLSDTEEMVANQKPPSSDYKVVKAQLQEQKFLKKMLLDRQNSMGSLANLGKEVA- 6620
            .::..|.||:|||.||                           ..|:.:..|.|.|.:|..|:: 
Human  1549 MKKEAASLSEWLSATE---------------------------TELVQKSTSEGLLGDLDTEISW 1586

  Fly  6621 --NHCEPGERASIEKQLNDLMKRFDALTDGAEQRELDLEEAMEVAKRFHDKISP-LELWLDNTER 6682
              |..:..|:...:  ||.:.:...||.:..|..|..|||.:.|......::.. .|.|.:....
Human  1587 AKNVLKDLEKRKAD--LNTITESSAALQNLIEGSEPILEERLCVLNAGWSRVRTWTEDWCNTLMN 1649

  Fly  6683 SVKAMELIPTDEEKIQQRIREHDRLHDEILGKKPDFSDLADVTAQLMHLVSDEEAVNLGEKVRGV 6747
            ....:|:...:...|...:.:.:.|.||| .|||. |...::   :..|||:.:..||  :|..|
Human  1650 HQNQLEIFDGNVAHISTWLYQAEALLDEI-EKKPT-SKQEEI---VKRLVSELDDANL--QVENV 1707

  Fly  6748 TERYTGLVDASDNIGALLAESRQGLRHLVLSYQDLVAWMESMEAELKR-FKSVP--VYAEKLL-- 6807
            .::            ||:..:.:|     .|.::||   |...|||.| |:.|.  :.:.|||  
Human  1708 RDQ------------ALILMNARG-----SSSRELV---EPKLAELNRNFEKVSQHIKSAKLLIA 1752

  Fly  6808 -EQMDHLLELNENIA-----GHASNVESTVESGAELM-KHI-SNDEAIQLKDKLDSLQRRYGDLT 6864
             |.:...|...|...     .....:|:.:|:..:.: ||: |:||    .:|:|....:..::.
Human  1753 QEPLYQCLVTTETFETGVPFSDLEKLENDIENMLKFVEKHLESSDE----DEKMDEESAQIEEVL 1813

  Fly  6865 NRGGDLLKSAQNALPLVQQFHEAHNRLVEWMQSAEAALAPSEPRQADVLRLEGELADMRPILDSI 6929
            .||.::|             |:                 |.|..:.:.:||:..|...|  .:.|
Human  1814 QRGEEML-------------HQ-----------------PMEDNKKEKIRLQLLLLHTR--YNKI 1846

  Fly  6930 NQVGPQLCQLSPGEGAATIESIVTRDNRRFDSIVEQIQRKAERLHLSNQRAKEVTGDIDELLEWF 6994
            ..:..|  |...|:.|:.|.|.:...    |.:||                      |:::|...
Human  1847 KAIPIQ--QRKMGQLASGIRSSLLPT----DYLVE----------------------INKILLCM 1883

  Fly  6995 REMDTTLREADLPAMEPKLVRAQLQEHRSINDDISSQKGRVRDVTAASKKVLRESPQSENTATLR 7059
            .:::.:|...:|              :.:|.:|.|.|:..::::.....|:      .|..|.:.
Human  1884 DDVELSLNVPEL--------------NTAIYEDFSFQEDSLKNIKDQLDKL------GEQIAVIH 1928

  Fly  7060 EKLDDL---------KEIVDTVAQL----------CSERLGILEQALPLSEHFADSHQGLTAWLD 7105
            ||..|:         .:|.||:.||          .|:|.|..::|:.....|......||.|:.
Human  1929 EKQPDVILEASGPEAIQIRDTLTQLNAKWDRINRMYSDRKGCFDRAMEEWRQFHCDLNDLTQWIT 1993

  Fly  7106 DMEQQISRLSMP--ALRPDQITLQQDKNERLLQSIAEHKPLLDKLNKTGEALGALVADDDGAKIN 7168
            :.|:.:.....|  :|..::..:.|   :.|...|:.|:|....||:||:.:...::..||:.:.
Human  1994 EAEELLVDTCAPGGSLDLEKARIHQ---QELEVGISSHQPSFAALNRTGDGIVQKLSQADGSFLK 2055

  Fly  7169 EILDTDNARYAALRLELRERQQALESALQESSQFSDKLEGMLRALANTVDQVNQLDPLSALPQKI 7233
            |.|...|.|:.|:..|:::||..|:.   ||.|.                            .|.
Human  2056 EKLAGLNQRWDAIVAEVKDRQPRLKG---ESKQV----------------------------MKY 2089

  Fly  7234 REQIEDNDALMDDLDKRQDAFSAVQRAANDVIAKAGNKADPAVRDIKAKLEKLNNLWNDVQNATK 7298
            |.|:   |.::..|.|   |..|:|:.:...:.:...:.....::::...|||..|     |.|:
Human  2090 RHQL---DEIICWLTK---AEHAMQKRSTTELGENLQELRDLTQEMEVHAEKLKWL-----NRTE 2143

  Fly  7299 KRGSSLDDILSVAEPFWKQLNSVMKTLKDLEETLS--CQEPPAA------QPQDIKKQQVALQEI 7355
            ....| |..||:.|     .:.:.::|:.:..|.:  |:|.|..      :|..:.:.::|    
Human  2144 LEMLS-DKSLSLPE-----RDKISESLRTVNMTWNKICREVPTTLKECIQEPSSVSQTRIA---- 2198

  Fly  7356 RHEIDQTKPEVEQVRRHGSNLMNMCGEPDKPEVKKHIEDLDNAWDNITALYAKREENLIDAMEKA 7420
                  ..|.|::|       :.:....|.| |:.|                :..|..|.|    
Human  2199 ------AHPNVQKV-------VLVSSASDIP-VQSH----------------RTSEISIPA---- 2229

  Fly  7421 MEFHETLQNLLKFLTKAEDKF-AHLGAVGSDIDAVKRQIEQLKSFKDEVDPHMVEVEALNRQAVE 7484
             :..:|:..|..:|...:... :::..|| |::.:.:.:.::|..|.:::....:::.:...|..
Human  2230 -DLDKTITELADWLVLIDQMLKSNIVTVG-DVEEINKTVSRMKITKADLEQRHPQLDYVFTLAQN 2292

  Fly  7485 LTER-TSPEQAASIREPLSVVNRRWEALLRGMVERQKQLEHALLHLGQFQHALNELLVWINKTDS 7548
            |..: :|.:...:|.|.|..|..:|:....|:..||:|||..::...|:.....|....:.|.::
Human  2293 LKNKASSSDMRTAITEKLERVKNQWDGTQHGVELRQQQLEDMIIDSLQWDDHREETEELMRKYEA 2357

  Fly  7549 TLDQLKPIPGDPQLLEVELAKLKVLANDIQAHQNSVDTLNDAGRQLIETEKGSVEASTTQEKLRK 7613
            .|..|:....||  |..:::..::|..::......|...::..::|:| |.||.:....:|....
Human  2358 RLYILQQARRDP--LTKQISDNQILLQELGPGDGIVMAFDNVLQKLLE-EYGSDDTRNVKETTEY 2419

  Fly  7614 LNNEWKQLLQKASDRQHELEEALREAHGYIAEVQDILGWLGD----VDAVIGASKPVGGLPET-- 7672
            |...|..|.|..:|||:.||...|.......::::.|.|:.:    |:.::.||.....|.::  
Human  2420 LKTSWINLKQSIADRQNALEAEWRTVQASRRDLENFLKWIQEAETTVNVLVDASHRENALQDSIL 2484

  Fly  7673 ATEQLERFMEVYNELDENRPKVETIQAQGQEYIKRQNQMKVSSSNLQHTLRTLKQRWDAVVSRAS 7737
            |.|..::..::..|:|.:....::|....|:.:|.....: .::.|||.|..:.|||:.:.::::
Human  2485 ARELKQQMQDIQAEIDAHNDIFKSIDGNRQKMVKALGNSE-EATMLQHRLDDMNQRWNDLKAKSA 2548

  Fly  7738 DKKIKLEIALKEATEFHDTLQAFVEWLTQAEKLLSNAEPVSRVLETIQAQMEEHKVLQKDVSTHR 7802
            ..:..||.:.::......:|:..::||...::.|....|:...:..:|.|.:..|.|::::....
Human  2549 SIRAHLEASAEKWNRLLMSLEELIKWLNMKDEELKKQMPIGGDVPALQLQYDHCKALRRELKEKE 2613

  Fly  7803 EAMLLLDKKGTHLKYFSQKQDVILIKNLLVSVQHRWERVVSKAAERTRALDHGYKEAREFNDAWS 7867
            .::|                                           .|:|    :||.|     
Human  2614 YSVL-------------------------------------------NAVD----QARVF----- 2626

  Fly  7868 GMMQYLQETEQVLDQIIEEATASKEPQKIKKYIGKLKETHRQLGAKQSVYDGTMRTGKNLLERAP 7932
                       :.||.||   |.:||:             |.|.:|      |..|.:...::..
Human  2627 -----------LADQPIE---APEEPR-------------RNLQSK------TELTPEERAQKIA 2658

  Fly  7933 KGDRPVLDKMLIELKEQW------TRVWSKSIDRQRKLEEALLLSGQFSDALGELLDWLKKAKSR 7991
            |..|    |...|:||:|      |..|.|.:|  :.||:...|.|...|...:    :|:|:|.
Human  2659 KAMR----KQSSEVKEKWESLNAVTSNWQKQVD--KALEKLRDLQGAMDDLDAD----MKEAESV 2713

  Fly  7992 LNENGPVHGDLETVQGLCEHHKHIEQDLQKRAAQMQGVLKTGRDLERSGNNP-------EVGRQL 8049
            .|...|| ||| .:..|.:|.:.| ...::..|.:...:||..||. |..:|       ::.|||
Human  2714 RNGWKPV-GDL-LIDSLQDHIEKI-MAFREEIAPINFKVKTVNDLS-SQLSPLDLHPSLKMSRQL 2774

  Fly  8050 DEMQSIWEEVKSAVAKRGERLQVALVDAEKLNARVQALFDWLDHAEHKLRYAKNAPDDEKVSREM 8114
            |::...|:.::.:|..|.::||             :|..|:...::|.|..:...|....:|...
Human  2775 DDLNMRWKLLQVSVDDRLKQLQ-------------EAHRDFGPSSQHFLSTSVQLPWQRSISHNK 2826

  Fly  8115 MDIHMDFMKDLRVREREK-TETFEYAEDIIN---KAYPDAIPIIKNWLSIIQQRWEEVRQWAINR 8175
            :..:::........:..| ||.|:...|:.|   .||..||.|.:...::.....|......|.:
Human  2827 VPYYINHQTQTTCWDHPKMTELFQSLADLNNVRFSAYRTAIKIRRLQKALCLDLLELSTTNEIFK 2891

  Fly  8176 ESKLEQHLQSLKDLDDTIEELLAWLSGLE-----------------GTLLN---------LKHEQ 8214
            :.||.|:.| |..:.|.|..|.....|||                 ..|||         ::.:.
Human  2892 QHKLNQNDQ-LLSVPDVINCLTTTYDGLEQMHKDLVNVPLCVDMCLNWLLNVYDTGRTGKIRVQS 2955

  Fly  8215 LPDEIPPVEK-LIEDHKEFMENTARRQNEVDRACKPRQ----LPPGARKPSRSGKTPVFKGS 8271
            |...:..:.| |:|:...::........|:   |..||    |....:.|.:.|:...|.||
Human  2956 LKIGLMSLSKGLLEEKYRYLFKEVAGPTEM---CDQRQLGLLLHDAIQIPRQLGEVAAFGGS 3014

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
shotNP_725339.1 SAC6 204..>420 CDD:227401
CH_PLEC-like_rpt2 223..327 CDD:409038
SPEC 471..689 CDD:238103
SPEC 690..866 CDD:238103
SH3_10 864..929 CDD:407754
SPEC 1047..1250 CDD:238103
SPEC 1153..1390 CDD:238103
PLEC <1498..1526 CDD:197605
Plectin 1949..1980 CDD:459901
DUF5585 2860..>3198 CDD:465521
SMC_prok_B <4936..>5564 CDD:274008 127/686 (19%)
SPEC 5304..5513 CDD:238103 43/235 (18%)
SPEC <5658..5787 CDD:413338 39/141 (28%)
SPEC 5793..6007 CDD:238103 38/217 (18%)
SPEC 6011..6220 CDD:238103 40/221 (18%)
SPEC 6118..6330 CDD:238103 46/218 (21%)
PRK09039 <6279..6441 CDD:181619 28/161 (17%)
SPEC 6443..6660 CDD:238103 47/219 (21%)
SPEC 6663..6878 CDD:238103 50/228 (22%)
SPEC 6880..7087 CDD:238103 39/225 (17%)
SPEC 6986..7196 CDD:238103 50/230 (22%)
SPEC 7196..7417 CDD:238103 39/228 (17%)
SPEC 7314..7526 CDD:238103 39/221 (18%)
SPEC 7528..7747 CDD:238103 48/224 (21%)
SPEC 7749..7968 CDD:238103 40/224 (18%)
SPEC 7973..8181 CDD:238103 50/218 (23%)
FRQ1 <8375..8444 CDD:444056
GAS2 8450..8522 CDD:128539
PHA03307 8550..>8795 CDD:223039
UTRNNP_009055.2 actin-binding domain 1..246 41/255 (16%)
CH_UTRN_rpt1 31..137 CDD:409081 19/117 (16%)
CH_UTRN_rpt2 152..255 CDD:409083 17/104 (16%)
Interaction with SYNM. /evidence=ECO:0000269|PubMed:16777071 268..905 141/710 (20%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 284..303 3/18 (17%)
spectrin-like triple coiled-coil repeat 309..2797 625/3159 (20%)
SPEC 310..528 CDD:238103 51/252 (20%)
SPEC 530..>646 CDD:413338 22/124 (18%)
SPEC 803..1013 CDD:238103 52/225 (23%)
SPEC 910..1123 CDD:238103 56/278 (20%)
Spectrin 6. /evidence=ECO:0000255 910..1012 27/108 (25%)
Spectrin 7. /evidence=ECO:0000255 1019..1121 26/160 (16%)
Spectrin 8. /evidence=ECO:0000255 1128..1229 25/149 (17%)
SPEC 1132..1336 CDD:238103 47/266 (18%)
SPEC 1235..1446 CDD:238103 54/284 (19%)
Spectrin 9. /evidence=ECO:0000255 1236..1333 22/110 (20%)
Spectrin 10. /evidence=ECO:0000255 1335..1436 29/139 (21%)
Interaction with SYNM. /evidence=ECO:0000269|PubMed:16777071 1336..1768 124/610 (20%)
SPEC 1440..1649 CDD:413338 58/300 (19%)
Spectrin 14. /evidence=ECO:0000255 1748..1848 26/135 (19%)
Spectrin 15. /evidence=ECO:0000255 1849..1968 29/166 (17%)
SPEC 1977..2179 CDD:238103 54/252 (21%)
Spectrin 16. /evidence=ECO:0000255 1979..2080 26/103 (25%)
Spectrin 17. /evidence=ECO:0000255 2087..2186 25/115 (22%)
Spectrin 18. /evidence=ECO:0000255 2229..2332 21/108 (19%)
SPEC 2230..2442 CDD:238103 47/215 (22%)
Spectrin 19. /evidence=ECO:0000255 2349..2439 21/92 (23%)
Spectrin 20. /evidence=ECO:0000255 2446..2555 20/109 (18%)
SPEC 2450..2690 CDD:238103 60/331 (18%)
Spectrin 21. /evidence=ECO:0000255 2562..2687 37/213 (17%)
SPEC 2692..>2808 CDD:238103 33/136 (24%)
Spectrin 22. /evidence=ECO:0000255 2694..2796 29/109 (27%)
Interaction with SYNM. /evidence=ECO:0000269|PubMed:16777071 2798..3165 47/221 (21%)
WW domain 2812..2845 2/32 (6%)
WW 2817..2845 CDD:238122 2/27 (7%)
cys-rich domain 2877..3117 30/142 (21%)
EFh_UTRO 2882..3043 CDD:320005 30/137 (22%)
EF-hand-like motif 2882..2921 CDD:320005 13/39 (33%)
EF-hand-like motif 2928..2962 CDD:320005 4/33 (12%)
EF-hand-like motif 2968..3004 CDD:320005 7/38 (18%)
EF-hand-like motif 3017..3043 CDD:320005
ZZ domain 3064..3111
ZZ_dystrophin 3068..3116 CDD:239074
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 3357..3390
Blue background indicates that the domain is not in the aligned region.

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