DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment shot and Gas2

DIOPT Version :9

Sequence 1:NP_725339.1 Gene:shot / 36542 FlyBaseID:FBgn0013733 Length:8805 Species:Drosophila melanogaster
Sequence 2:XP_006229335.1 Gene:Gas2 / 499156 RGDID:1563167 Length:332 Species:Rattus norvegicus


Alignment Length:400 Identity:85/400 - (21%)
Similarity:133/400 - (33%) Gaps:166/400 - (41%)


- Green bases have known domain annotations that are detailed below.


  Fly  8170 QWAINRESKLEQHLQSLKDLDDTIEELLAWLSGLEGTLLNLKHEQLPDEIPPVEKLIEDHKEFME 8234
            ||..:|.   |.:|..:|      |:|..||:.|.|..:..                   :.|||
  Rat    24 QWLASRH---EANLLPMK------EDLALWLTNLLGKEITA-------------------ETFME 60

  Fly  8235 NTARRQNEVDRACKPRQLPPGARKPSRSGKTPVFKGSRDQGLNARKGSRITPTRDTPDRDRLPHY 8299
                   ::|......||....::.        ||.|.|    ..|.::..|.:..|.:...|. 
  Rat    61 -------KLDNGALLCQLAATVQEK--------FKESMD----TNKPAKTLPLKKIPCKASAPS- 105

  Fly  8300 GPRFSPSTSGPELEFRSPRAKLLWTKWRDVWMLSWERQRLLNDHLLYLKDVERARNFSWDDWRKR 8364
            |..|:...:..                    .|||                  .|:...|:    
  Rat   106 GSFFARDNTAN--------------------FLSW------------------CRDLGVDE---- 128

  Fly  8365 FLKYMNHKKSRLTDLFRKMDKDNNGMI----PRDVFIDGILNTKFDTSGLEMKAVADLFDRNGEG 8425
                        |.||     ::.|::    ||:|.:          ..||:..:|..:.....|
  Rat   129 ------------TCLF-----ESEGLVLHKQPREVCL----------CLLELGRIAARYGVEPPG 166

  Fly  8426 L------IDWQEFIAALRPDWQERKPANDS-------DKIHDEVKRLV--MLCTCRQKFRVFQVG 8475
            |      |:.:|.::|..|   ...|::.|       :.:.|.|||:.  ..|.|..||.|.::.
  Rat   167 LIKLEKEIEQEETLSAPSP---SPSPSSKSSGKKSTGNLLDDAVKRISEDPPCKCPTKFCVERLS 228

  Fly  8476 EGKYRFGDSQKLRLVRILRST-------------------VMVRVGGGWVALDEFLQKNDPC--- 8518
            :|:||.|  :|:..:|.|.|.                   |||||||||.....:|.|:|||   
  Rat   229 QGRYRVG--EKILFIRGLHSCAYVSTAKAEQTRKMLHNKHVMVRVGGGWETFAGYLLKHDPCRML 291

  Fly  8519 ---RAKGRTN 8525
               |..|:|:
  Rat   292 QISRVDGKTS 301

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
shotNP_725339.1 SAC6 204..>420 CDD:227401
CH 223..327 CDD:306753
SPEC 471..689 CDD:238103
SPEC 690..866 CDD:238103
SH3 885..922 CDD:327375
SPEC 1047..1250 CDD:238103
SPEC 1153..1390 CDD:238103
PLEC <1498..1526 CDD:197605
Plectin 1949..1981 CDD:307019
DNA_pol3_delta2 <2711..3178 CDD:331068
DUF4775 3026..3357 CDD:330579
SMC_N <4904..5566 CDD:330553
SPEC 5304..5513 CDD:238103
SPEC <5658..5787 CDD:321951
SPEC 5793..6007 CDD:238103
SPEC 6011..6220 CDD:238103
SPEC 6118..6330 CDD:238103
PRK09039 <6279..6441 CDD:332967
SPEC 6443..6660 CDD:238103
SPEC 6663..6878 CDD:238103
SPEC 6880..7087 CDD:238103
SPEC 6986..7196 CDD:238103
SPEC 7196..7417 CDD:238103
SPEC 7314..7526 CDD:238103
SPEC 7528..7747 CDD:238103
SPEC 7749..7968 CDD:238103
SPEC 7973..8181 CDD:238103 3/10 (30%)
EF-hand_7 8373..8437 CDD:316058 15/73 (21%)
GAS2 8450..8522 CDD:128539 32/98 (33%)
Herpes_ICP4_C 8550..>8795 CDD:332854
Gas2XP_006229335.1 CH 36..158 CDD:237981 37/235 (16%)
GAS2 201..292 CDD:295345 31/92 (34%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG0516
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
32.810

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