Protein Alignment shot and Kcp

DIOPT Version :9

• Sequence 1: NP_725339.1
• Gene: shot / 36542
• FlyBaseID: FBgn0013733
• Length: 8805
• Species: Drosophila melanogaster
• Sequence 2: XP_011239372.1
• Gene: Kcp / 333088
• MGIID: 2141640
• Length: 2120
• Species: Mus musculus
• Alignment Length: 888
• Identity: 165/888 - (18%)
• Similarity: 275/888 - (30%)
• Gaps: 301/888 - (33%)

  Fly  6009 DGR--HFAENCSKTL-----------------------GW---LGGELSNLTDRLL------VSA 6039
            |||  ||..:||..|                       .|   :...|..:..|||      |..
Mouse  1297 DGRLLHFQGSCSYVLAKDCHGEDFSVHVTNDDRGRRGVAWTQEVAVLLGTVAVRLLQGRTVMVDQ 1361

  Fly  6040 HKPTLQHQIDTHEPIYRE----VMAREHEVIMLINKG-KDLTDRQQDRGVK-------------- 6085
            |..||        |..||    :..|.|.||:....| :.|.|.|....|:
Mouse  1362 HTVTL--------PFLREPLLYIELRGHTVILHAQPGLQVLWDGQSQVEVRVPSSYRGQTCGLCG 1418

  Fly  6086 -------------------------------------------RDLDRIQQQWEKLRREAVDRHT 6107
                                                       |::|..:....:.||||..|..
Mouse  1419 NFNGFAQDDLQGPDGRLLPTEASFGNSWKVPKGLGPGRPCSAGREVDPCRAAGYRARREANARCG 1483

  Fly  6108 RLQTC-MEHCKKYSQTSETFLAWLRTAEDKLADLTPGVLSKAKLETRLRD-LQTFRSE------- 6163
            .|:|. ..||.........|.|.:.    .|....||..|    :|.|.| |:.:.|.
Mouse  1484 ILKTSPFSHCHAVVPPEPFFAACVY----DLCACGPGSSS----DTCLCDALEAYASHCRQAGVT 1540

  Fly  6164 -VWKHSGEFENTKGLGETFLS-SCDIDKEPIK------------------------AELQDIRDR 6202
             ||:......|...:.:|.|. ...:|..|..                        .|::..:..
Mouse  1541 PVWRGPTLCGNHSWVSKTPLQPQASLDPVPTSLPALCRSRPASKCLTAGLELPMTLLEMEGSQRA 1605

  Fly  6203 WERLNNDL--------------------------IARAHEIENCSRRLDDFNDELRNLDHSLGRC 6241
            .|:|..||                          .|::...::..|.:|:..::|     |...|
Mouse  1606 QEKLLWDLELLTGVGLGLFWPPWAGYCSQRSQTQYAQSQCSQSWGRSVDEDFEQL-----SSKLC 1665

  Fly  6242 ------EDRLAAHDALGG-------AAKDPKLLERVKAIREELTNLSKPLQSLKALAKDISAEAR 6293
                  |....:|..|.|       :|.|   ||..::..:  ..|..|:...||:....:.|.:
Mouse  1666 PPPQAGEAHSESHQLLKGKLATDSSSASD---LEEARSDGD--PRLEGPIMPAKAVPGSSTGEGQ 1725

  Fly  6294 AAGG------DADHLTSEVDGLADRMSELQ--GRLDDRCGELQSAATAVSQFNEQMKSLGIDLND 6350
            .|||      ...|.|:.........|||:  |::::|.   |:.....|.|.:.::|
Mouse  1726 EAGGAGVPGAGCLHSTNSSSFKEPGNSELKDPGKMEERS---QAEPNIQSSFGQTLRS------- 1780

  Fly  6351 LETEIEKLSPPGREIKIVQVQIDDVGKIQTKLDRLVGRLEDAERAA--DVLVDAGFAADTTQTR- 6412
              |:..||...|.|...:..|  .:..:| .|.:.:|.....||||  .:|...|...:|.|.:
Mouse  1781 --TQEGKLGQEGPEPSDLASQ--GLSALQ-DLSKGLGSGLSQERAAPQTLLTPQGHPEETPQGQR 1840

  Fly  6413 ---------EQISTLRKTLGRLDNRVRDHEDNLHSTLKALREFYDHQSQTLDDIQDVSDEFKRMK 6468
                     |.|....|.:.:..:..:..:......:..|:|  ..:|:..:::|..:..:::
Mouse  1841 GQSPQGYKGESIQGQDKGVPQSQSERKQAQQGQEFKIPPLQE--GSKSEVWEEVQRGATVWRQ-- 1901

  Fly  6469 PVGSELDQIRRQQEDFRNFRERKVEPLAINVDKVNVAG-----RDLVRSAGSGVSTTAIEKDLEK 6528
                |.|:.:....||....|:   |:..:|:| .:||     ..:.::|.:...|.|.....:.
Mouse  1902 ----EEDKPQGHPSDFCKSPEK---PIPQHVEK-GIAGPQGGSTQVTQAAATQEGTWAPPTPPQL 1958

  Fly  6529 LNDRWNDLKERMNERDRRLDVALLQSGKFQEALAGLSKWLSDTEEMVANQKPPSSDYKVVKAQLQ 6593
            .......|.....||..||..||                   .|:.|.....||.|
Mouse  1959 QGPEGGILVSEAQERQPRLPSAL-------------------REQRVPRDPKPSKD--------- 1995

  Fly  6594 EQKFLKKMLLDRQNSMGSLANLGKEVANHCEPGERASIEKQLNDLMKRFDALTDGAEQRELDLEE 6658
                   ...:.:|...:||:.|:||.........|:.:::..|           .||:.|.:.|
Mouse  1996 -------AWPEPRNREDALASAGQEVLQRLLELNGAARQRRRRD-----------REQQRLRVLE 2042

  Fly  6659 AMEVAKRFHDKISPLELWLDNTERSVKAMELIPTDEEKIQQRI 6701
            .:.:....|.::.||.|.....:::       |.::...:|||
Mouse  2043 RLRILANHHRRVYPLGLLPSVAQKA-------PQEDRAGRQRI 2078

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
shot	NP_725339.1	SAC6	204..>420	CDD:227401
		CH	223..327	CDD:306753
		SPEC	471..689	CDD:238103
		SPEC	690..866	CDD:238103
		SH3	885..922	CDD:327375
		SPEC	1047..1250	CDD:238103
		SPEC	1153..1390	CDD:238103
		PLEC	<1498..1526	CDD:197605
		Plectin	1949..1981	CDD:307019
		DNA_pol3_delta2	<2711..3178	CDD:331068
		DUF4775	3026..3357	CDD:330579
		SMC_N	<4904..5566	CDD:330553
		SPEC	5304..5513	CDD:238103
		SPEC	<5658..5787	CDD:321951
		SPEC	5793..6007	CDD:238103
		SPEC	6011..6220	CDD:238103	62/365 (17%)
		SPEC	6118..6330	CDD:238103	53/292 (18%)
		PRK09039	<6279..6441	CDD:332967	37/181 (20%)
		SPEC	6443..6660	CDD:238103	41/221 (19%)
		SPEC	6663..6878	CDD:238103	8/39 (21%)
		SPEC	6880..7087	CDD:238103
		SPEC	6986..7196	CDD:238103
		SPEC	7196..7417	CDD:238103
		SPEC	7314..7526	CDD:238103
		SPEC	7528..7747	CDD:238103
		SPEC	7749..7968	CDD:238103
		SPEC	7973..8181	CDD:238103
		EF-hand_7	8373..8437	CDD:316058
		GAS2	8450..8522	CDD:128539
		Herpes_ICP4_C	8550..>8795	CDD:332854
Kcp	XP_011239372.1	VWC	166..220	CDD:278520
		VWC	224..280	CDD:327433
		VWC	285..341	CDD:327433
		VWC	344..399	CDD:327433
		VWC	458..514	CDD:278520
		VWC	517..573	CDD:327433
		VWC	634..690	CDD:327433
		VWC	<717..753	CDD:327433
		VWC	931..987	CDD:327433
		VWC	<1173..1214	CDD:214564
		VWC	1221..1278	CDD:214564
		VWD	1285..1432	CDD:365869	29/142 (20%)
		C8	1482..1549	CDD:370094	17/74 (23%)
		Glutenin_hmw	<1757..>1975	CDD:367362	46/244 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1216
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900