Protein Alignment shot and Clmn

DIOPT Version :9

• Sequence 1: NP_725339.1
• Gene: shot / 36542
• FlyBaseID: FBgn0013733
• Length: 8805
• Species: Drosophila melanogaster
• Sequence 2: XP_017449593.1
• Gene: Clmn / 299285
• RGDID: 1306741
• Length: 1107
• Species: Rattus norvegicus
• Alignment Length: 1025
• Identity: 203/1025 - (19%)
• Similarity: 352/1025 - (34%)
• Gaps: 296/1025 - (28%)

  Fly   160 VRKVT-TLSRAEENAQPAEDLLPPAKMIRSSELEYRRALPPAIESSSTQRREISDIVVGKEDNVS 223
            ::::| .|||:..::.     |.|......|:..|    ||   :.:|:|    .:.|..:|...
  Rat   195 IKELTGNLSRSSPSSS-----LSPGSGGTDSDSSY----PP---TPTTER----SVAVAVKDQRK 243

  Fly   224 AREALLRWARRSTARYPGVRVNDFTSSWRDGLAFSALVHRNRPDLLDWRKARNDRPRERLETAFH 288
            |.:.||.|.:|.|.:| ||.|.||..|||.||||.|::....|.|:|.::|..|..||.||.||.
  Rat   244 AIKTLLSWVQRKTRKY-GVAVQDFAGSWRSGLAFLAVIKAIDPSLVDMKQALEDSTRENLEKAFR 307

  Fly   289 IVEKEYGVTRLLDPEDVDTNEPDEKSLITYISSLYDVFPE--------PPSIHPL---------F 336
            |......:.|||:|||:..:.|||:|::||::...:.|||        |....|:         .
  Rat   308 IAHDSLHIPRLLEPEDIMVDMPDEQSIVTYVAQFLERFPELDPEDFVNPDKEAPIESTFVRIKES 372

  Fly   337 DMESQRRVHEYRDLAQQFIYWCREKTAYLQERSFPPTLIEMKRLLSDLQRFRSDEVSARKREKSK 401
            ..|.:.||.......:| .|....:|::.     ||..:.:...|.....|......:.|...|.
  Rat   373 PSEQESRVLLLSQNGEQ-PYTVSHETSHP-----PPDKVFVCDQLESPTGFSLGSAPSHKLPDSP 431

  Fly   402 LIQIYKELERYFE-TVGEVDVEAELRPDAIEKAWYRMNTALQDREVILQQEIERLERLQRLADKV 465
            ...:::.:::.|: ::|..:...|..|:         ::.|..|
  Rat   432 TDFMHQIIDQVFQASMGNTESTTEPTPE---------SSILSTR--------------------- 466

  Fly   466 QREIKHVDQKLTDLEGRIGEEGRRIERLHPVDAKSIVEALETEIRHLEEPIQ---DMNQDCHVLN 527
                               ::|||...| || .||:         |.|..:.   ..::|....:
  Rat   467 -------------------KDGRRSNSL-PV-KKSV---------HFETDLHKDASCSKDPFYSS 501

  Fly   528 EGRYPHVSELHKKVNKLHQRWAQLRTNFHTNLVQKLSGLKYPVHETTVTRQTRMVVESRQ----- 587
            |.|:....:..|:::|         .:.|.:|.: :|..|.|..|      .|:|:|:..
  Rat   502 EFRFEGSPKATKELSK---------QDGHASLAE-VSKEKKPEQE------ARLVLEAASDKAPE 550

  Fly   588 ---IDTNPHFRDLQ--EHIEWCQNKLKQLLAADYGSDLPS---------------------VKEE 626
               :||:...:|.|  :...:|...::.  .|..|...||                     ..|.
  Rat   551 DTIVDTDAMSQDAQLPQDSSFCNGNVEN--PASLGEKGPSPPSPRDNTILANSVELKVPLLTVEP 613

  Fly   627 LDRQQH-----------EHKIIDQFHTK--ILNDERQQTKFSGDELAL--YQQR--LNQLQKVYA 674
            :|:..:           ...::|...|.  .:.|.....|..|:|...  |.::  ..:.:..:|
  Rat   614 MDKDDYFECIPLKASKFNRDLVDFASTSQAFVEDPSSHKKTPGEEEGSENYTEKPGKRKSKSPHA 678

  Fly   675 ELLSTSTKRLSDL-------DSLQHFLGQ------ASAELQWLNEKEQVEITRDWADKQLDL--- 723
            |..||.: ||..:       |..|...|.      |:.:...:.||.:.:.||..::::.:.
  Rat   679 ETESTES-RLEPIKLETPPKDPEQEDQGHTLPPETAADKKPEVYEKAKRKSTRHHSEEEGEAEGG 742

  Fly   724 ------------PSVHRYYENLMSELEKREMHFATILDRGEALLNQQHPASKC------------ 764
                        ||.....|.|.|..|:.       ||     .....|.||.
  Rat   743 LSAVGGEMPSNPPSTSVSLETLRSHSEEG-------LD-----FKPSPPLSKISVIPHDLFYYPH 795

  Fly   765 IEAHLTALQQQWAWLLQLTLCLEVHLKHATEYHQFFGEIKDAEQWLAKRDEILNSKFSQSDFGLD 829
            .|..|.|:.:.:|...:.....:..|:|..  ..:..:.::.|:...:.:|..:|..|..:|.|.
  Rat   796 YEVPLAAVLEAYAEGGEDLKSEDADLEHPD--GSYLQDSREEEEEEDEEEEEAHSSHSSCNFSLP 858

  Fly   830 QGETLLRGMQDLREELNAFGETVATLQRRAQTVVPLNKRRQPV--NRQGPVQAICAYKQQGQLQI 892
            ...:..| :.|....::...|...:.......  |.::..||:  ...|||::     ||.|..
  Rat   859 VDNSYPR-VNDHVSHVDGSSEGPTSASEPGSP--PSHEDHQPMETKENGPVES-----QQSQEP- 914

  Fly   893 EKGETVTLLDNSGRVKWRVRTAKGQEGPIPGACLLLPPPDQEAIDAAERLKRLFDRSVALWQKKH 957
                                                |.|:.......|:|..:...|....::||
  Rat   915 ------------------------------------PTPELSTKPLEEKLTEVPTSSKKKEKRKH 943

  Fly   958 LRLRQNMIFATIRVVKGWDFDQFLAMGP-EQRTAIRRALNDDA-------DKLLSEGDPNDPQLR 1014
            :...::.:|.....|:..|   .|...| |.:...|.:.:|.:       ::.|.....:..|||
  Rat   944 MDHVESSLFIAPGTVRSSD---DLEENPCEHKVPSRNSHSDSSIYIRRHTNRSLELDHFSYVQLR 1005

  Fly  1015 RLRREMDEVNRLFDEFEKRARAEEESKQASRIFTEECLAIKSKLEDMARE 1064
            ......|..|||.:.:.            |:..||..|.......||.||
  Rat  1006 NAADVDDRRNRLLNRYN------------SQKLTELILQFYGIRADMKRE 1043

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
shot	NP_725339.1	SAC6	204..>420	CDD:227401	67/233 (29%)
		CH	223..327	CDD:306753	44/103 (43%)
		SPEC	471..689	CDD:238103	48/275 (17%)
		SPEC	690..866	CDD:238103	34/208 (16%)
		SH3	885..922	CDD:327375	3/36 (8%)
		SPEC	1047..1250	CDD:238103	7/18 (39%)
		SPEC	1153..1390	CDD:238103
		PLEC	<1498..1526	CDD:197605
		Plectin	1949..1981	CDD:307019
		DNA_pol3_delta2	<2711..3178	CDD:331068
		DUF4775	3026..3357	CDD:330579
		SMC_N	<4904..5566	CDD:330553
		SPEC	5304..5513	CDD:238103
		SPEC	<5658..5787	CDD:321951
		SPEC	5793..6007	CDD:238103
		SPEC	6011..6220	CDD:238103
		SPEC	6118..6330	CDD:238103
		PRK09039	<6279..6441	CDD:332967
		SPEC	6443..6660	CDD:238103
		SPEC	6663..6878	CDD:238103
		SPEC	6880..7087	CDD:238103
		SPEC	6986..7196	CDD:238103
		SPEC	7196..7417	CDD:238103
		SPEC	7314..7526	CDD:238103
		SPEC	7528..7747	CDD:238103
		SPEC	7749..7968	CDD:238103
		SPEC	7973..8181	CDD:238103
		EF-hand_7	8373..8437	CDD:316058
		GAS2	8450..8522	CDD:128539
		Herpes_ICP4_C	8550..>8795	CDD:332854
Clmn	XP_017449593.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900