DRSC/TRiP Functional Genomics Resources

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Protein Alignment shot and Gas2l2

DIOPT Version :9

Sequence 1:NP_725339.1 Gene:shot / 36542 FlyBaseID:FBgn0013733 Length:8805 Species:Drosophila melanogaster
Sequence 2:NP_001099293.2 Gene:Gas2l2 / 287570 RGDID:1307868 Length:857 Species:Rattus norvegicus


Alignment Length:444 Identity:115/444 - (25%)
Similarity:158/444 - (35%) Gaps:141/444 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly  8443 RKPANDSDKIHDEVKRLVMLCTCRQKFRVFQVGEGKYRFGDSQKLRLVRILRSTVMVRVGGGWVA 8507
            |:|.: ...:...|:.||..|||..:|.:.::.:||||.|||..|..:|||||.|||||||||..
  Rat   198 RRPCH-FHNLDQMVQSLVSHCTCPVQFSMVKISDGKYRVGDSNTLIFIRILRSHVMVRVGGGWDT 261

  Fly  8508 LDEFLQKNDPCRAKGRTNIE-------------LREQFILADGVSQSMAAFTPRRS--------- 8550
            |..:|.|:||||.   |::.             ::.:..:.||.||.....|..||         
  Rat   262 LGHYLDKHDPCRC---TSLSHKPGSFLKPPGPPVQHEVKVQDGPSQPQPLMTISRSQSPLPPVDW 323

  Fly  8551 -------------TPNAAATASSSPHAHNGGSSNLPPYMSGQGPIIKVRERSVRSIPMSRPS-RS 8601
                         ||     :||.|.:.....:..|..|:   |.::.:|:...|..||.|. :.
  Rat   324 KTYTSSSRKLRPPTP-----SSSGPRSEFPARARTPREMA---PFLRSQEKPTLSQRMSSPGPQL 380

  Fly  8602 SLSASTPDSLSDNEGSHGGPSGRYTPRKVTYTSTRTGLTPGGSRAGSKPNS---RPLSRQGSKPP 8663
            |.....||..|                  |.:..|...:||....|..|.|   :....||:...
  Rat   381 SSPCRGPDLQS------------------TLSERRVNRSPGELPRGRTPTSWVPKEADSQGAHTK 427

  Fly  8664 SRHGSTLSL-DSTDDHTPSRIPQRKPSTGSTAS----------------------------GTTP 8699
            :.....|.: ::|...||:|.|...|.:.|.||                            |.|.
  Rat   428 APIPQRLQIPETTSKKTPARGPSPPPRSSSLASPHTIWLPDQGASPEISEPMSAQSSSPGKGLTK 492

  Fly  8700 RPARLSVTTTTTPGSRLNGTSTITRKTASGSASPAPTSNGGMSRSS-SIPALTGFGFKPIRRNIS 8763
            .|.|||.....|||....||.                ..|.|.|.| |..||.|    .:.|:..
  Rat   493 IPIRLSPARPPTPGRGSLGTE----------------GGGSMQRGSLSSRALAG----NLDRSTH 537

  Fly  8764 GSST-------------PSGMQTPRKSSAEPTFSSTMRRTSRGTT-PTEK-REP 8802
            |..:             .||.:.||.       ..|..|..|.|: |..: |||
  Rat   538 GHHSVDVSKDHQKVIQISSGTEDPRS-------LGTQERKERYTSLPLGRTREP 584

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
shotNP_725339.1 SAC6 204..>420 CDD:227401
CH 223..327 CDD:306753
SPEC 471..689 CDD:238103
SPEC 690..866 CDD:238103
SH3 885..922 CDD:327375
SPEC 1047..1250 CDD:238103
SPEC 1153..1390 CDD:238103
PLEC <1498..1526 CDD:197605
Plectin 1949..1981 CDD:307019
DNA_pol3_delta2 <2711..3178 CDD:331068
DUF4775 3026..3357 CDD:330579
SMC_N <4904..5566 CDD:330553
SPEC 5304..5513 CDD:238103
SPEC <5658..5787 CDD:321951
SPEC 5793..6007 CDD:238103
SPEC 6011..6220 CDD:238103
SPEC 6118..6330 CDD:238103
PRK09039 <6279..6441 CDD:332967
SPEC 6443..6660 CDD:238103
SPEC 6663..6878 CDD:238103
SPEC 6880..7087 CDD:238103
SPEC 6986..7196 CDD:238103
SPEC 7196..7417 CDD:238103
SPEC 7314..7526 CDD:238103
SPEC 7528..7747 CDD:238103
SPEC 7749..7968 CDD:238103
SPEC 7973..8181 CDD:238103
EF-hand_7 8373..8437 CDD:316058
GAS2 8450..8522 CDD:128539 36/71 (51%)
Herpes_ICP4_C 8550..>8795 CDD:332854 65/313 (21%)
Gas2l2NP_001099293.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..21
CH 33..159 CDD:237981
GAS2 206..274 CDD:366964 35/67 (52%)
PHA03307 278..>527 CDD:223039 59/290 (20%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 282..572 70/342 (20%)
Interaction with ADORA2A. /evidence=ECO:0000250|UniProtKB:Q5SSG4 432..857 43/180 (24%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 670..716
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 759..857
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG0516
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
32.810

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