Protein Alignment shot and D2096.11

DIOPT Version :10

• Sequence 1: NP_725339.1
• Gene: shot / 36542
• FlyBaseID: FBgn0013733
• Length: 8805
• Species: Drosophila melanogaster
• Sequence 2: NP_001379846.1
• Gene: D2096.11 / 177638
• WormBaseID: WBGene00017078
• Length: 727
• Species: Caenorhabditis elegans
• Alignment Length: 801
• Identity: 184/801 - (22%)
• Similarity: 302/801 - (37%)
• Gaps: 209/801 - (26%)

  Fly  7958 IDRQRKLEEA---LLLSGQFSDALGELLDWLK-----------KAKSRLNENGPVHGDLETVQGL 8008
            |.:...|:|:   ||:|.|.|..:.:|...||           |.|..:...|| ..|.:.:..|
 Worm    33 ISKDEALQESPSLLLVSKQVSKKIEQLKVLLKLVEEKKDTFISKCKLVMRTAGP-ESDAKELDSL 96

  Fly  8009 CEHHKHIEQDLQKRAAQMQGVLKTGRDLERSGNNPEVGRQLDEMQSIWEEVKSAVAKRGERLQVA 8073
            .:|.:....|:.:..:..:|::    |...:.|                 :.|......|.|.:|
 Worm    97 MKHVEDAYSDVFELISDKEGLI----DRFNASN-----------------INSDSVPNTESLNLA 140

  Fly  8074 ------------LVDAEKLNARVQALFDWLDHAEHK--LRYA---KNAPDDEKVSREMMDIHMDF 8121
                        |:|||.:        |..::.:.|  :.|.   .|||.|.::||........|
 Worm   141 FAAADPEFGAGRLLDAEDV--------DTNNNPDEKPVITYVSSLNNAPQDPEMSRLAASGGKGF 197

  Fly  8122 MKDLRVREREKTETFE----YAEDIINKAYPDAIPIIKNWLSIIQQRWEEVRQWAINRESKLEQH 8182
            .:::...:.:....||    .::|...:..|..:...|              |...|:..||::.
 Worm   198 EEEIGKLQADADHIFEALAVMSKDEALQESPSLLLYSK--------------QIRFNKIQKLKEL 248

  Fly  8183 LQSLKDLDDTIEELLAWLSGLEGTLLNLKHEQLPDEIPPVEKLIED-HKEFMENTARRQNEVDRA 8246
            |:.:::..||      ::|..:..:.....|....|:..:.|.:|| :.:..|..:.::..:||
 Worm   249 LKPVEEKKDT------FISECKLVMKTAGPEADTKELDSLLKQVEDAYSDVFELISDKEGLIDR- 306

  Fly  8247 CKPRQLPPGARKPSRSGKTPVFKGSRDQGLNARK--GSRITPTRDTPDRDRLPHY---------- 8299
            |....:  .:...|.:.:..:...:.|....|.:  .:....|.:.||...:..|
 Worm   307 CNASNI--NSDSVSNTERLNIALAAADAEFGAGRLLDAEDVDTNNNPDEKSIITYVSSLNNAFPL 369

  Fly  8300 GPRFSP--STSGPELEFRSPRAKLLWTKWRDVWMLSWERQRLLNDHLL-YLKDVERARNFSWDDW 8361
            .|..|.  ::.|..||             .::..|..:.     ||:. .|:::.:.........
 Worm   370 EPEMSKYVASGGKRLE-------------EEIGKLQADA-----DHIFKALEEISKDEALQESPS 416

  Fly  8362 RKRFLKYMNHKKSRLTDLFRKMDKDNNGMIPRDVFIDGILNTKFDTSGLE--MKAVADLFD---- 8420
            .....|.::.|..:|..|.:.:::..:..|.....:...:..:.|...|:  ||.|.|.:.
 Worm   417 LLLDSKQVSKKIEQLKVLLKPVEEKKDTFISESKLVMKTVGPESDAKELDSLMKHVEDAYSDVVE 481

  Fly  8421 --RNGEGLIDWQEFIAALRPDWQER--KPANDSDKIHDEVKRLVMLCTCRQKFRVFQVGEGKYRF 8481
              .:.|||||        |.:...|  .|..:::||.:|::.|...|:|...:::.::.|..|||
 Worm   482 LISDKEGLID--------RCNASNRIAHPQTETEKITNEIELLKETCSCCTPYQIEKISENYYRF 538

  Fly  8482 GDSQKLRLVRILRSTVMVRVGGGWVALDEFLQKNDPCRAKGRTNI----ELREQFILADGVSQSM 8542
            ||:...|:||||||||||||||||..|:|.|||:||||.|||.||    |.|....|     ..|
 Worm   539 GDTHIKRMVRILRSTVMVRVGGGWEPLEESLQKHDPCRTKGRLNINMFPEARPIHAL-----DLM 598

  Fly  8543 AAFTPRRSTPNAAATASSSPHAHNGGSSNLPPYMSGQGPIIKVRERSVRSIPMSRPSRSSLSAST 8607
            .:||..|             ||..      .|.....|||:|:||::.||:|||
 Worm   599 QSFTKNR-------------HAKQ------MPIAGTPGPIMKIREKTERSVPMS----------- 633

  Fly  8608 PDSLSDNEGSHGGPSGRYT-----PRKVTYTSTRTGLTPGGSRAGSKPNSRPLSRQGSKPPSRHG 8667
                    |..||.:| ||     |||......|...||.....|         ||     ||.|
 Worm   634 --------GGLGGTAG-YTVTTESPRKTPQRPFRIPRTPSDKTPG---------RQ-----SRVG 675

  Fly  8668 --STLSLDSTDDHTPSRIPQR 8686
              |.|.....:..:||:...|
 Worm   676 CVSNLKNSIVEPSSPSQSESR 696

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
shot	NP_725339.1	SAC6	204..>420	CDD:227401
		CH_PLEC-like_rpt2	223..327	CDD:409038
		SPEC	471..689	CDD:238103
		SPEC	690..866	CDD:238103
		SH3_10	864..929	CDD:407754
		SPEC	1047..1250	CDD:238103
		SPEC	1153..1390	CDD:238103
		PLEC	<1498..1526	CDD:197605
		Plectin	1949..1980	CDD:459901
		DUF5585	2860..>3198	CDD:465521
		SMC_prok_B	<4936..>5564	CDD:274008
		SPEC	5304..5513	CDD:238103
		SPEC	<5658..5787	CDD:413338
		SPEC	5793..6007	CDD:238103
		SPEC	6011..6220	CDD:238103
		SPEC	6118..6330	CDD:238103
		PRK09039	<6279..6441	CDD:181619
		SPEC	6443..6660	CDD:238103
		SPEC	6663..6878	CDD:238103
		SPEC	6880..7087	CDD:238103
		SPEC	6986..7196	CDD:238103
		SPEC	7196..7417	CDD:238103
		SPEC	7314..7526	CDD:238103
		SPEC	7528..7747	CDD:238103
		SPEC	7749..7968	CDD:238103	3/12 (25%)
		SPEC	7973..8181	CDD:238103	43/239 (18%)
		FRQ1	<8375..8444	CDD:444056	16/78 (21%)
		GAS2	8450..8522	CDD:128539	38/71 (54%)
		PHA03307	8550..>8795	CDD:223039	37/144 (26%)
D2096.11	NP_001379846.1	CH_SF	<117..180	CDD:469584	13/91 (14%)
		CH_SF	<315..368	CDD:469584	7/52 (13%)
		GAS2	507..579	CDD:128539	38/71 (54%)