Protein Alignment shot and vab-10

DIOPT Version :9

• Sequence 1: NP_725339.1
• Gene: shot / 36542
• FlyBaseID: FBgn0013733
• Length: 8805
• Species: Drosophila melanogaster
• Sequence 2: NP_001335521.1
• Gene: vab-10 / 173058
• WormBaseID: WBGene00006876
• Length: 5059
• Species: Caenorhabditis elegans
• Alignment Length: 8715
• Identity: 1599/8715 - (18%)
• Similarity: 2699/8715 - (30%)
• Gaps: 3986/8715 - (45%)

  Fly    97 GNSRRLSETGALVPAGAIPTSSTHYQQVTRNKRISTEVLGSSVESTKTSQRAPNGH-----RRVT 156
            |:.:.:|..|.....|.  .:|::|::.                |::......|||     .::.
 Worm   197 GSQQAISGGGGAGAGGG--GNSSYYEEY----------------SSRNGAAGGNGHVGNGGGQII 243

  Fly   157 THIVRKVTTLSRAEENAQPAEDLLPPAKMIRSSELEYRRALPPAIESSSTQRREISDIVVGKEDN 221
            .|      ..::...|||.|.     .....||..|.|......::.....|.|......||.|:
 Worm   244 HH------AHNQHLSNAQQAH-----GGFSESSSYETREHFERKVQRVKKTRGERERSRSGKRDD 297

  Fly   222 V--------SAREALLRWARRSTARYPGVRVNDFTSSWRDGLAFSALVHRNRPDLLDWRKARND- 277
            |        |||:|||:||||.||.||.|.||:|:|||||||||:|::||.|...:||.|..:|
 Worm   298 VSLHGSDATSARDALLQWARRVTAGYPRVNVNNFSSSWRDGLAFNAILHRYRSSAIDWNKISSDS 362

  Fly   278 -RPRERLETAFHIVEKEYGVTRLLDPEDVDTNEPDEKSLITYISSLYDVFPEPPSIHPLFDMESQ 341
             ...|||..||...::|:||.||||.||||||.|||||:|||:||||:..|..|.:..|     |
 Worm   363 VSNTERLNNAFAAADREFGVERLLDAEDVDTNNPDEKSIITYVSSLYNALPHEPEMSRL-----Q 422

  Fly   342 RRVHEYRDLAQQFIYWCREKTAYLQERSFPPTLIEMKRLLSDLQRFRSDEVSARKREKSKLIQIY 406
            :...||.:.|.::..|.......:.:|....|..|   |:.:|||||.|::..|:.:|.:|..:|
 Worm   423 KVQEEYIEEAYEWREWVVRAIQLVDDRHLQGTASE---LIYELQRFREDDLPPREEQKRRLTLVY 484

  Fly   407 KELERYFETVGEVDVEAELRPDAIEKAWYRMNTALQDREVILQ----QEIERLERLQRLADKVQR 467
            :.||:...:.....:..||....:::.|..:..::..|..:|:    ||....:.|.|||    |
 Worm   485 EHLEKVMRSTELFAIPHELSAPELQRVWNELQNSIDRRFDVLERHRIQEGNSNDLLSRLA----R 545

  Fly   468 EIKHVDQKLTDLEGRIGEEGRRIERLHPVDAKSIVEALETEIRHLEEPIQDMNQDCHVLNEGRYP 532
            .|...::||..:..||.:...|::...|...:..|..:..::..||.||....:|...|...::|
 Worm   546 GIGITNEKLDLILKRIEDVEARVDTSPPAAVERTVSEIVDDLNALESPIARFFEDVEELKSMQHP 610

  Fly   533 HVSELHKKVNKLHQRWAQLRTNFHTNLVQKLSGLKYPVHETTVTRQTRMVVESRQIDTNPHFRDL 597
            ..::.:|:|..||||    ||.:...|..::. ::..|...::.::.:..:|:.:   ...|..:
 Worm   611 EANDFYKQVYGLHQR----RTTYLDRLTNQIL-VRLGVRTDSLHKENQQRLENMR---KTSFSRV 667

  Fly   598 QEHIEWCQNKLKQLLAADYGSDLPSVKEELDRQQHEHKIIDQFHTKILNDERQQTKFSGDELALY 662
            :|.|||.:.::::|...::..||.:::...::.:.:::.|..|...:.....:|.:.|.::...|
 Worm   668 EECIEWVRVRMEKLTTMEFLEDLETLEHVFEQHKFDNRDIQDFRQNVDECIARQAEVSAEDTYEY 732

  Fly   663 QQRLNQLQKVYAELLSTSTKRLSDLDSLQHFLGQASAELQWLNEKEQVEITRDWAD-KQLDLPSV 726
            .:.|..|:..|.:|...|..|:.|||||..|:..|..||.|::|:|.:|:||:|:| ||||||.:
 Worm   733 CELLRVLESEYQQLRDLSAGRMLDLDSLIAFVRAAQLELIWVSERESIEVTRNWSDIKQLDLPML 797

  Fly   727 HRYYENLMSELEKREMHFATILDRGEALLNQQHPASKCIEAHLTALQQQWAWLLQLTLCLEVHLK 791
            ..||:.|:.|:|.||..:..:.::|.|||||.|||.:.||.:|..:|.||.|||.|:.|||.||:
 Worm   798 TNYYKQLLHEMELREKQYNDVHNQGAALLNQGHPAIRVIEVYLRQMQSQWDWLLALSKCLEEHLR 862

  Fly   792 HATEYHQFFGEIKDAEQWLAKRDEILNSKFSQSDFGLDQGETLLRGMQDLREELNAFGETVATLQ 856
            .|.....|..|..|||.|:.::...|.:.::::||.|::||..||.:.:::|.||.:.:.:..|.
 Worm   863 DALNLKSFMEEASDAEAWIQEQSVRLENNYNRTDFSLEEGERFLRELDEIKEILNKYHQVLMALT 927

  Fly   857 RRAQTVVPLNKRRQPVNRQGPVQAICAYKQQGQLQIEKGETVTLLDNSGRVKWRVRTAKGQEGPI 921
            .|..::.||.:|.:.:.....|.|:|.|..: .:.|:.|:.|.|||||..:||.:|...|.||.:
 Worm   928 ERCASISPLWQRGERIPHPIKVTALCDYSDE-NVTIKAGDDVYLLDNSDLIKWTIRDISGAEGQV 991

  Fly   922 PGACLLLPPPDQEAIDAAERLKRLFDRSVALWQKKHLRLRQNMIFATIRVVKGWDFDQFLAMGPE 986
            |.....:||.|........||.:.|::...||.|||..:|.||:..|:|.::|||.|.|.::.|:
 Worm   992 PSVVFRIPPTDARLTALLNRLLQQFEKLKKLWDKKHRMVRFNMVLNTMRTIQGWDLDTFNSIDPD 1056

  Fly   987 QRTAIRRALNDDADKLLSEGDPNDPQLRRLRREMDEVNRLFDEFEKRARAEEESKQASRIFTEEC 1051
            ||.||.:||||||:|||||.|||||...|||.|:...|..|......::...|...||: :.::.
 Worm  1057 QRDAIMKALNDDANKLLSELDPNDPLALRLREELRRTNEHFWNLLNASQKPPEPDWASQ-YDQKM 1120

  Fly  1052 LAIKSKLEDMARELDQIILAPLPRDLDSLEHVLEIHSDYERRLHLLEPELKHLQETFRTIALKTP 1116
            ..:..|||:..|||:..:..|:.|..:.||.|:..|..:|..|..|:.::.:::|.||.:...||
 Worm  1121 AELLKKLEEAWRELNDAVGKPISRSPEDLERVIHAHKRFEDALQALDSDVANVKELFRQLPNPTP 1185

  Fly  1117 VLKKSLDNLMELWKELNTQSGLHKDRLKLLEASLAGLEDNEHVISELENELARHQDLPSTAEGLQ 1181
            ..:.:.|.|..||.:|...|.::.:|:|:||:.|.|:.:...::.:.|..|....|||:..:.|:
 Worm  1186 TQRVNHDRLNGLWDDLWDLSRMYVERIKVLESVLNGMVEVADIVRQHEITLNSFDDLPAALDKLR 1250

  Fly  1182 QVFKQLNHMQDIITQQQPQMDKMNDAADQLGRMGVPTKV----LGDLKRLHSNVERLNTRWSAVC 1242
            ....||..:..::.|||..:|::|.....|.:....|::    ..|:..:...|::||.||..|.
 Worm  1251 GHHSQLLEINMVLKQQQTVIDQLNRNVALLRQHVSRTRINEGHHPDVDAIEDEVQKLNVRWENVN 1315

  Fly  1243 NQLGERMRSCETAIGLMKNLQSSVQVEESWVDGTTERLSAMPTATS------AYELDKLLGAAI- 1300
            :|:..|:.:.|:|:.:....:|..:.|.||:|...|.::.:.....      ..:||.|:....
 Worm  1316 SQIASRLLAVESALQIQMVYRSEYETEMSWLDTVEETINRLRKPEELRPEQYQQQLDMLIAEYTN 1380

  Fly  1301 --ERKPKIENVNVAGGRLIREAKIYDSKCLRFVDWLVEAR-PSFSPPRRDLRPADSDPGATQYYS 1362
              |....||:||..|||.|.||||:|:|..::.|.:|... |......|..:|...:  .:|..:
 Worm  1381 LQEHTQAIEHVNKEGGRFIHEAKIFDAKLGQYSDGIVGIHGPGIKSEFRRTKPQPKN--GSQIVT 1443

  Fly  1363 QRLDNLNTKNDRL----------LEQLSQRLKTAIEVNGSDGLQYAES----LQKPLKTFRVDFS 1413
            :.|:.||.:..:|          ::.|.|..|...:.|.:..:.:.|:    :...|..||
 Worm  1444 EELELLNRRFAQLSSLILERRNTMQVLIQNWKRQKQENVTQVVSFREAEVSGMMTDLTRFR---- 1504

  Fly  1414 AGSVPTGDGYAARQEDLYTT--TYSTTQISSTKTTKSSTKSVYSSDGLDAASQEVSTAGLPQSQI 1476
                          ::::||  |:::                 :.:.:|||::.|
 Worm  1505 --------------QEIFTTHLTFNS-----------------NPESIDAATKNV---------- 1528

  Fly  1477 QFNEIRTLKRSQQLGGHSVLDIAGIRDPRTGRVLTIGEAIQLRILDVRTGEMLVGDRRITLEQAA 1541
                 :.:|:|        ||  ..||           .|:.|:.::        ||..|.|
 Worm  1529 -----QNVKQS--------LD--SWRD-----------RIKERLDEI--------DRLCTEE--- 1556

  Fly  1542 DQGLIDLQLAKQLLEPGAGRDASGRELSLLEVIQREISEAESGYETAEKRIKVNNTVTVEQTSGE 1606
                              |...:..:.|.|..::|::::.   |:|..:        |||.....
 Worm  1557 ------------------GDSLTPEQYSALREMRRQLADE---YDTVLR--------TVEGIHTR 1592

  Fly  1607 LGSPENPRNIADAITAGSVDTKTGLYRVKSGQTISLAEAYERGYLIRHESVTIKSNALCLSDAIA 1671
            |       ||..|:                              ||...|||....:
 Worm  1593 L-------NILSAL------------------------------LIEFSSVTSSMQS-------- 1612

  Fly  1672 HGLVDGAGWIADR---------NSGDKFRLDSA--IANQLIDASVREVVDAKRDTKITLQEALQS 1725
                    |:.||         .|||..|:|.|  .|..|:|..:||
 Worm  1613 --------WMTDRTRLAGDIRHKSGDPMRIDEARFEAKSLMDEVIRE------------------ 1651

  Fly  1726 GVLNAKTGRYVNEVTKEKLTFAEARNRQLIVKPYTLKDICDLNLLDKQAQITSPMRREKLSIMQA 1790
                                  |:|                                     ::.
 Worm  1652 ----------------------ESR-------------------------------------LKT 1657

  Fly  1791 IEAGVLDGNLLKCITKRKGELVTLQEAI-ADGIVLPAECKYRDFMTGELISIPEAVERGLISSVA 1854
            |.|.||         |.:.|:..:::.: |.|
 Worm  1658 IGASVL---------KIEQEISAMRDDVRASG--------------------------------- 1680

  Fly  1855 QRSIFDIDGFKDLRSNDYVSFNVALSRDLLRRKSTGFALETGRDSLVPLEVAVSEGLVRQEVYEM 1919
                          |.|.|..:|                                    .||||
 Worm  1681 --------------STDDVGISV------------------------------------DEVYE- 1694

  Fly  1920 FSRGIGVQNASGKELSVFDLVYHNLIDPKTGYLLDPKTGETVPLDTAIERKFITPEGALLLSSLL 1984
                                                                             
 Worm  1695 ----------------------------------------------------------------- 1694

  Fly  1985 NITLTTETVTRTINRYVTIRAGSQEPVDSVLLTFTEAVRQGFIDEERQLFKDPKTGNIYSVQQAL 2049
                                                 .|:...|:..||.:  :..::.|.|..|
 Worm  1695 -------------------------------------TRRRVEDDYMQLLR--QCQDLISFQNRL 1720

  Fly  2050 NYGLLVPDSNQTVPEPTNRKKTKSTITIVTKQIIPEAEPIKLNTQHTKYVEKSVEIPISQELVKP 2114
            :                                       .:|.:|::...::.|
 Worm  1721 H---------------------------------------AMNDEHSEQARRADE---------- 1736

  Fly  2115 HRVVSEFINLEKSSYIEQNVTERQIMELPPGGWRLKDAIEQRLFNPDTGVFHVQGTDRLVNFEEC 2179
                                            |.      |.|.|      .|:..|:
 Worm  1737 --------------------------------WL------QMLQN------DVEDVDQ------- 1750

  Fly  2180 INKQIINNLSLSVIDPNTGDKISVQSAFERDILDSYGNYTNSRKQVQGMRSAIDESKIILETVPA 2244
                          ||.          |:||
 Worm  1751 --------------DPR----------FQRD---------------------------------- 1757

  Fly  2245 TRGANQKTILRITKVNNIPDVLEVSTPLKDAPPKFVEVLTCQRELASPEPLQIAPGAIYDPSTAL 2309
                 :..|.||.::|.:
 Worm  1758 -----EDRIQRIEELNRM----------------------------------------------- 1770

  Fly  2310 VIFTQTGETENIFDAARQGLVDEQLIKIVDPTTKQPISVTEAIARSIYDPKTATILDSEGQPVDL 2374
                ..|.:..:.||                         |..:|.:
 Worm  1771 ----AAGGSSQLDDA-------------------------EQASRRL------------------ 1788

  Fly  2375 ITATKLGLLSVVGAPLVAAEGALRTVRFVTDPRTGEQIPVEVAYERGIVSRDQLHRGRSFDSEPA 2439
                           |.|.||    .....|.|...:   |:|         .|.||:
 Worm  1789 ---------------LTALEG----TNVANDVRARHE---ELA---------NLRRGK------- 1815

  Fly  2440 TVEDKVVVLQRMRKVILKPKDALRKGIIDEETCEILENTSNFTNPKGEVVNITEALNTGLIDGRR 2504
                                   .:.:||..:..::|..|.    |.|...:.:|
 Worm  1816 -----------------------HQKVIDRLSQNMMEAASR----KAEAEGVKQA---------- 1843

  Fly  2505 GQVIDPQNNRVLNLRQAVEQKIIDSEQTNHILMPLAKSLSVPRLADQGLIDPQTQTIVHPESGYP 2569
                      |.||||..||....:.|.  :.:||.:
 Worm  1844 ----------VENLRQWSEQTAQRTRQP--VQLPLTE---------------------------- 1868

  Fly  2570 LSIHEAIVCEVLDPHSKLHKPEKCTLEEAITKGIINADDSTFNYKNKTLNITEAIEAKLFDPSYD 2634
            |.:|||                                                        ..|
 Worm  1869 LDLHEA--------------------------------------------------------RKD 1877

  Fly  2635 QQKSKVEIPPVGMIFPVAVEKSLVEPSKRVVLHPSTKKALPIKQAIEENFIMSIPYSPKPDAIEV 2699
            :|                            |||
 Worm  1878 EQ----------------------------VLH-------------------------------- 1882

  Fly  2700 VTAMEQDLIDVAAQTLTVPSTGERIPLRQAMENGVLVVKNLSDFVITQKPIPKTEIMETVRAVHT 2764
                                 ||       :||.:.:::.|
 Worm  1883 ---------------------GE-------IENRLALIEEL------------------------ 1895

  Fly  2765 VTTKTIELMQGYVLISNNEVQNVNTGEVCSLEEAKELGILREESTTRETKAAAGESPESVGDVGT 2829
                              |.:..:.|:..||.|.:|..:..:.|.
 Worm  1896 ------------------EKKAADVGDHASLAELQECKMKLKRSN-------------------- 1922

  Fly  2830 SGDQTVIVEERTQTVVVSSDTRKQEMQVVSTTQSTKDTSVPSVSEIETKGSKEPSKTLQNVKDAA 2894
                                         |..:..:|....:::.::|..|:  .:||....|:|
 Worm  1923 -----------------------------SDLKGLRDNIFDAINGLQTVNSE--GETLSRAVDSA 1956

  Fly  2895 KLGALGVIAAPVLAGGAIVSGVKSLIKSVKSPTEDAKSTEKPKEPQTSFIEQERRKELQPQQVPS 2959
                                |.|  |:|.:.|                             :..|
 Worm  1957 --------------------GAK--IRSARLP-----------------------------EAQS 1970

  Fly  2960 EVDNLLSETENFISSTTANFIANEKQQDKPDTLPQESNLPLEVESTSTLTTTTVTTITTSSTTTE 3024
            ||:.|                     ||:.|
 Worm  1971 EVEAL---------------------QDQAD---------------------------------- 1980

  Fly  3025 TGNLEPVVVEDVSTTVKEDKVVVKPSTVPEDKTEVSKITETITTVTSNETDTVPEKISQKSASEE 3089
              |||                               :||..:..:
 Worm  1981 --NLE-------------------------------RITNNLCNI-------------------- 1992

  Fly  3090 SAKKDPVVTKDTSSRPAETETSPKPVQKEPTPDPAQNTEFPESIKKDPTPEPDYKETATEAAQIT 3154
                                                                             
 Worm  1993 ----------------------------------------------------------------- 1992

  Fly  3155 PKEASPAPTNKNEQSAEPTSKPEPMPRTAKKEEISEIEPPFTAPLAPFVDQLAETKITEIKTEFK 3219
                                                                             
 Worm  1993 ----------------------------------------------------------------- 1992

  Fly  3220 EPVTSSQTITTITTTVKTVDEHPIVEEVDEVSKSEKIVDVEEPTVHQQEPIKVNETSDDSTRTEP 3284
                                                      |.|               |||||
 Worm  1993 ------------------------------------------PNV---------------TRTEP 2000

  Fly  3285 TNEIVHEERVVTVEEPTITETTVTTTTITTTTTSSSEETLPQENTATVKETPLNEPVPSSPAETK 3349
                                                                             
 Worm  2001 ----------------------------------------------------------------- 2000

  Fly  3350 EIEQTTNDDQKKPEEIVDTEKKTTEQKPVETIPTEPISTSETTTVTLTTKTTIVDEGKLHPPSDI 3414
             :.|.:.|.:|:
 Worm  2001 -VIQKSKDLRKR----------------------------------------------------- 2011

  Fly  3415 EQIIQPHSTSDKHQSLVDFIEQEKGTQPAEGGSNILQNVKDAAKLGALAIVGAPVLAGKALVDAL 3479
                            ||...||..                 |::|.||
 Worm  2012 ----------------VDSCAQELD-----------------ARMGKLA---------------- 2027

  Fly  3480 TTEKTLKPEHSTSQVVTETVEELPTEIITTSTATLVTKVTTTTTTTTTSTSEGTPDDEALDVVKL 3544
                                 ||                                  |:||
 Worm  2028 ---------------------EL----------------------------------ESLD---- 2033

  Fly  3545 PAELVESSVKREVPRTLAIGDAISQKLISPDECQVIVDGEQQSQTVSTLLKEEQLSPLDEVQIID 3609
             ||.                |....||               |..:...  :::|..|::|.|..
 Worm  2034 -AEF----------------DGAKNKL---------------SSFIGAF--DDELKGLEKVSIDK 2064

  Fly  3610 DKLIVLQQVSYLVDADTELTPQNLYELNIYDPENQYFIDPSTGQKISFHTLVFDMNVFNPETILV 3674
            :||           |:.....|:
 Worm  2065 EKL-----------AEQRRQTQD------------------------------------------ 2076

  Fly  3675 KNFSTGKYETLTAALERPLLDRHTGHMVDPKTGKKIPFFECVDRQWIIRANPEEQKPSGIENVTI 3739
                              |:|:|:
 Worm  2077 ------------------LVDKHS----------------------------------------- 2082

  Fly  3740 DTQTGQVVLDDGRVCSIVEAINSGKLDIQSISVRDPVSGEVIPLRMAIELGVVDMQAGTVIDIQT 3804
               .|..:|||      ||||      .|.::..||
 Worm  2083 ---EGNAILDD------VEAI------AQKVTAEDP----------------------------- 2103

  Fly  3805 LKEIPMELAFQLGFLVPGARKPISLEAAVRKGLYDPETGKLFDSESQNQVDVQKSI-EIGLVDPK 3868
                                               .:||           ..|||: |:|
 Worm  2104 -----------------------------------SKTG-----------SAQKSVGELG----- 2117

  Fly  3869 ISLIVDTVTKKEVKLDCAIEDDLVLPATGQIKDNKNNTLVPFDVGVQQCLLKTDNVTWSLPELLQ 3933
                                                                         ..||
 Worm  2118 -------------------------------------------------------------ARLQ 2121

  Fly  3934 REYYTPSTGKVLNPVTGEEILLQQAIEMGFVELETTLVKDVDHDKILPGKEAAKVGLLDTVRGTL 3998
            |                      ||.|:                               ..||
 Worm  2122 R----------------------QASEL-------------------------------KARG-- 2131

  Fly  3999 SSPNISLDEAFVKGYLISTKKPLSLVDCLLRGLYDPSTAKFTIDDKQLDLKAAIAQKLINPEELV 4063
                                                        ||            ||.
 Worm  2132 --------------------------------------------DK------------INK---- 2136

  Fly  4064 LLDPKTESIISITEAIAKGYLDPIEGYVINPYASTKLSLHEALENRILIPPKRKRSLPDAVYRGL 4128
             ||.|..|... :||...||::                             |:|
 Worm  2137 -LDSKATSFAE-SEAAVLGYIE-----------------------------KQK----------- 2159

  Fly  4129 YDPKTGQFSNTVTREKLTTERAIRRGILDPDSTVVNVGSGQIIPFGVATETGIVDSKHGTVRDAD 4193
                          ::|:|
 Worm  2160 --------------DQLST---------------------------------------------- 2164

  Fly  4194 DHPIDFKEAFDRGILVEAKKPLRLIEAVVKNVYDEVDGHFVDPKSGEKLNFAEALNTNLLDEHSV 4258
                        |..|.|.|                                |.:.:.|||
 Worm  2165 ------------GFPVPATK--------------------------------EGVKSQLLD---- 2181

  Fly  4259 QIRDFKTGLYKQLNLTHAKDTGIIDAQNSKLLYNNQTMTLKHAFDIGILMDVNAPISIQRAIHQG 4323
                                                                     ::|.
 Worm  2182 ---------------------------------------------------------LERM---- 2185

  Fly  4324 LFDDKTGKLSDPRTGRQITLLESMRSFVVNPHLPCYFDEQTEQMYTLSETCRNGIINRREGVFRE 4388
               :||||                             :||                 ||
 Worm  2186 ---NKTGK-----------------------------EEQ-----------------RR------ 2195

  Fly  4389 PGSNSFVPLGEALSLGLIVDIENAGFGLYELLSMGFYETSTRKVLHPVTNRKLNLNEACVEDVVS 4453
                                                                             
 Worm  2196 ----------------------------------------------------------------- 2195

  Fly  4454 LSSSLVKHHETGKYLRLANAIKEQLVDDSRGCYNLGNEQLDLQAARARGLIVSNRRLLSLELVLR 4518
                                     |||:|
 Worm  2196 -------------------------VDDAR----------------------------------- 2200

  Fly  4519 QQLYRPETGKFCDPTTGEYLDLIEAIHSGFIDPATTVFKNQLTGKELPLTEAIENGDIDVSKGRV 4583
                                      ||.
 Worm  2201 --------------------------HSA------------------------------------ 2203

  Fly  4584 FDPKSKSAYNYDVALSRGILVTITRPLTDRNDVVRRQDSVELLNQTPVSVVISKPREMSLEEAIR 4648
                                                                   ||::.|
 Worm  2204 -------------------------------------------------------RELARE---- 2209

  Fly  4649 YNIIDPKTALVRDFDSFKFLPYSVAVERGLVDTTKRTLVDPKALYFAFDPTLIVYVREPVTFDQA 4713
                                   .:||:.:.|..:|
 Worm  2210 -----------------------ASVEKEVQDMNQR----------------------------- 2222

  Fly  4714 AESKCLDLQTGLLTYVPASVPGSATAAPASDDSANDSLTVIETPKVYTLKEAASAGVVDPDSALV 4778
             |.|.||..
 Worm  2223 -EKKLLDEW-------------------------------------------------------- 2230

  Fly  4779 KDLAKAKLVRLPEAFRKGLMDANKA-NVLNTQTSKLCTLQEAYESGLICTPKRSFGLLEAITFNL 4842
            :|||        :.|......|||| .|||.     |...|.|...
 Worm  2231 EDLA--------DQFDAVRSRANKAEQVLNE-----CAQMEKYIGA------------------- 2263

  Fly  4843 YNPTNGCLVDPFQMHPDIIRRRKFTLAEAIGSGLVDPSSTVVRDPSTGVIVPLTAAISSGLIDAT 4907
                                  |..:.|.||:            ||                  |
 Worm  2264 ----------------------KKNMLEGIGA------------PS------------------T 2276

  Fly  4908 EGRLTDANEPKNNIDLVKAAEKGLLLPAEQRQAVFEKFNMCEENVNDLLKWVTTVEQKISSVGGP 4972
            |..:..||  :..|..:||..:|      ::.|:        |:||.|
 Worm  2277 EPGVAKAN--RAQIQSMKAETEG------EKSAL--------EHVNSL----------------- 2308

  Fly  4973 REKIDELRNQINALKQIKDEIESQQRPVATCLEQIRQIVLTGGDVLSAPEVTTLENSGRELRSRV 5037
                                              ..:::..||        ..:|    ||..::
 Worm  2309 ----------------------------------ANELIADGG--------ANVE----ELMKKM 2327

  Fly  5038 DRVNDRTVRLLRRLEAGRDELTKLRSELDVFSDWLQVARRTLEDKERSLSDLTRLPSQADSVREF 5102
            ||:|    |....||:|.||                                     .|..|.|
 Worm  2328 DRLN----RKWHSLESGLDE-------------------------------------NAGRVEE- 2350

  Fly  5103 VSDVIGHQADLRFITMAAQKFVDESKEFLAILNDFRTSLPERLPHVEPLSSAESPIRQEVSLVSA 5167
                             |.|...|.|:   |..:.|..|.|          .||.:.:..::.|.
 Worm  2351 -----------------AAKLGQELKD---IQKELRKELGE----------LESNVEKASAMSSN 2385

  Fly  5168 QYKDLLNRVNALQDRVSGLGGRQREYQDALDKANEWLRSVHPRVSRIISEPIAGDPKGVQDQMNE 5232
            ...|.|..:::|:.|..|           :|||.|.|:.:......:  |..|.:...:|:|:..
 Worm  2386 DIGDQLATLDSLKSRFGG-----------VDKALEKLKGILEATEEL--EVDATNRAEIQEQLET 2437

  Fly  5233 AKALHNELLSSGRLVDNAQQALDNLLRSLGGQLSPMEINQLELPIADLKNNYQQLLDNLGEHCKT 5297
            .:...:||   .|.::|.::|..|
 Worm  2438 TQKKADEL---ERKIENVKKAALN----------------------------------------- 2458

  Fly  5298 LDKTLVQSQG--VQDALDSLVGWVNQAEDKFKMNLRPASLIKERLQEQIREHKVLLADLQSHQAS 5360
                 .|::|  ::..||.|:|.||.||::.:: ..|.:....:|.::::..:.|...|..::..
 Worm  2459 -----AQNEGLELEKKLDELIGTVNSAENELEL-AAPIAAESLKLADELKRAEELFQKLIENEGD 2517

  Fly  5361 IDSVQVSAKHLLASASNARIAKKVESNLNDVTVKFEKLYEKANKRGEFLDDVYNRLSRYLDEIST 5425
            :..::......|....:|.:.||:           |.||:|..|
 Worm  2518 VSLIRAKVAEELKKKPDAELKKKL-----------ELLYQKWPK--------------------- 2550

  Fly  5426 VEQRMASLQEALDSRETSLLSTEELARRMNELSRDKDQLAPQFEDCVRSGKDLISLRDVTDTGVL 5490
                      ||.:                  :||:..|..:..|.|:.               .
 Worm  2551 ----------ALGA------------------ARDRKDLVSKAGDLVKQ---------------F 2572

  Fly  5491 RDRIKALESQWRNINISIDERAKLSKQKAEQQLAYEGLKDQVLSWLASTEARVNGLPPVAIDLDR 5555
            .|:::|||.:.:.....:||  .|:..||......:.||                    .::|..
 Worm  2573 GDQVQALEQRLQGDQAELDE--LLASDKAHDPEVCDALK--------------------LVELTM 2615

  Fly  5556 IKQQHDELKPICKDYRDYAPTIDKINDIGAQYDALIRPESPARKRSTYSPIKRTSPLRR----MS 5616
            .::..|               :|.:|.:      :.|.||.|       |....:.|||    :|
 Worm  2616 ARRLAD---------------VDALNAV------MNRIESSA-------PGPDANRLRRRADTLS 2652

  Fly  5617 GDARSPSPTKGGILSPLSTGSSGFGSRRSSQDGFQLSELSPVQQQLSEINNRYGLIGVRLNDRQH 5681
            .||:                    |..:.::....|::
 Worm  2653 DDAK--------------------GMAKKARTAADLAQ--------------------------- 2670

  Fly  5682 ELDNLNEELRKQYENLKGLAQFLERIQRQLPKESVSNKDEAERCIKQARKILEDMYEKQSLLDTT 5746
                     |||     |||:..||:                 |           .|.....:..
 Worm  2671 ---------RKQ-----GLAKKFERL-----------------C-----------DEVSQFTENQ 2693

  Fly  5747 KAQVKDILRRKSDVPGAEQLRQENDSIQEKWKNLNDICKNRIAFSEKLRDFLDTHGNLKSWLDSK 5811
            ||:::|.:.:  |:..||:::.:.:.|.:.|
 Worm  2694 KAEIQDAIEK--DLLNAERVQSKLNKIDDFW---------------------------------- 2722

  Fly  5812 ERMLTVLGPISSDPRMVQSQVQQVQVLREEFRTQQPQLKHFQELGHDVVDHLAGTP-DAQAVEIK 5875
                      ||:.|                     :||:   :|.::  .:..|| |||||:.|
 Worm  2723 ----------SSNSR---------------------ELKN---VGDEI--KIDATPEDAQAVDTK 2751

  Fly  5876 LKDILGKWDDLVGKLDDRANSLGGAADSSKEFDAAVNRLREALQNISDNLDTLPTDGDHQENLRK 5940
            |.::....|.|:..|.:                          ||:            |.|..|:
 Worm  2752 LAELQAGIDGLLATLQE--------------------------QNV------------HLEEKRE 2778

  Fly  5941 IENLERQLEGQRPLLADVEQSAATLCNILGDPASRADVNSRVAALEKQYLALQKKLDTKKAETEA 6005
            ..| ..|.|.|:                     :...:||.||
 Worm  2779 QAN-RVQSESQK---------------------AAGKINSLVA---------------------- 2799

  Fly  6006 SLRDGRHFAENCSKTLGWLGGELSNLTDRLLVSAHKPTLQHQIDTHEPIYREVMAREHEVIMLIN 6070
                                 |:::|                    :||
 Worm  2800 ---------------------EIADL--------------------DPI---------------- 2807

  Fly  6071 KGKDLTDRQQDRGVKRDLDRIQQQWEKLRREAVDRHTRLQTCMEHCKKYSQTSETFLAWLRTAED 6135
                        |..||
 Worm  2808 ------------GRSRD------------------------------------------------ 2812

  Fly  6136 KLADLTPGVLSKAKLETRLRDLQTFRSEVWKHSGEFENTKGLGETFLSSCDIDKEPIKAELQDIR 6200
                                :||..:.||.:.:|:      ||..            :.::.::.
 Worm  2813 --------------------ELQKQKKEVVELAGD------LGSA------------QTKMLELG 2839

  Fly  6201 DRWERLNNDLIARAHEIENCSRRLDDFNDELRNLDHSLGRCEDRLAAHDALGGAAKDPKLLERVK 6265
            ..||.                                            |||.......:.|..:
 Worm  2840 AEWEA--------------------------------------------ALGAGIVAQPVFEMNR 2860

  Fly  6266 AIREELTNLSKPLQSLKALAKDISAEARAAGGDADHLTSEVDGLADRMSELQGRLDDRCGELQSA 6330
            |..:||..|:                |||               ..|:::
 Worm  2861 AATDELNKLA----------------ARA---------------GKRLAQ--------------- 2879

  Fly  6331 ATAVSQFNEQMKSLGIDLNDLETEIEKLSPPGREIKIVQVQIDDVGKIQTKLDRLVGRLEDAERA 6395
                                            ||.||.:.: |::.|:....|::||.||...:.
 Worm  2880 --------------------------------REKKITETE-DEIDKLHADADQIVGALEAIAKD 2911

  Fly  6396 ADVLVDAGFAADTTQTREQISTLRKTLGRLDNRVRDHEDNLHSTLKALREFYDHQSQTLDDIQDV 6460
            ..:........|..|..|::..|:::|
 Worm  2912 EALQGAPSQLLDPKQVSEKVRQLKESL-------------------------------------- 2938

  Fly  6461 SDEFKRMKPVGSELDQIRRQQEDFRNFRERKVEPLAINVD-KVNVAGRDLVRSAGSGVSTTAIEK 6524
                   ||||.::|                    |.|.| |:      |:::||....|..::.
 Worm  2939 -------KPVGEKMD--------------------AFNTDCKL------LIKTAGPESDTKELDS 2970

  Fly  6525 DLEKLNDRWNDLKERMNERDRRLDVALLQSGKFQEALAGLSKWLSDTEEMVANQKPPSSDYKVVK 6589
            .|:|:.|.::|:..::::::..:|.|:.|.||.::|...|..||.:||||:.|:|.||:|.||.|
 Worm  2971 LLKKVGDAYSDVVGKVSDKEMSVDAAVQQQGKVEDAYRALLNWLEETEEMMENRKKPSADAKVAK 3035

  Fly  6590 AQLQEQKFLKKMLLDRQNSM-GSLANLGKEVANHCEPGERASIEKQLNDLMKRFDALTDGAEQRE 6653
            |||.:.:.|.|.:.|::.|: |..|.:.|.||......|:.::..:...:..|:..|.:.|..|:
 Worm  3036 AQLHDYEVLMKHVEDKKPSVDGFKAMIEKIVAEASSDEEKKALGNKNAQIEDRYKDLLNSAVDRQ 3100

  Fly  6654 LDLEEAMEVAKRFHDKISPLELWLDNTERSVKAMELIPTDEEKIQQRIREHDRLHDEILGKKPDF 6718
            ..|.:|:::|:|..:...||:.||.:.::.::|:..:|...||.::.|.|.:.|.||:..|..|.
 Worm  3101 RKLLDAVDLAERLQEVTIPLDSWLQSADKRLQALAKVPITVEKAEEMIGEQEALQDELEHKSDDL 3165

  Fly  6719 SDLADVTAQLMHLVSDEEAVNLGEKVRGVTERYTGLVDASDNIGALLAESRQGLRHLVLSYQDLV 6783
            .|:.::...|..|||.|:|.::..:|..:..|...|.....|:..||....|.::...|..:|:.
 Worm  3166 KDVLEIAPMLASLVSVEDANSISGQVNQLEARARALDAGITNMRPLLESFLQQIQDFTLDAEDMT 3230

  Fly  6784 AWMESMEAELKRFKSVPVYAEKLLEQMDHLLELNENIAGHASNVESTVESGAELMKHISNDEAIQ 6848
            .::...|.:|.....:|:..:.|:||.:.|.|:..:||.....:.:..|.|.:|......:||:.
 Worm  3231 QFVGETEVKLGELDELPIEPDDLVEQTNILAEIAVSIADRDEMMANIFEVGKQLAIQGEPEEALI 3295

  Fly  6849 LKDKLDSLQRRYGDLTNRGGDLLKSAQNALPLVQQFHEAHNRLVEWMQSAEAALA---PSEPR-Q 6909
            .:.|||.|:.||.||.....:.:.....|:||.:.|||..:.:::.::..:..|.   ..:|. |
 Worm  3296 AQKKLDDLKFRYADLMTSADEKIALLAKAIPLSEGFHEGFDTVMQVLEDMDRDLQTIDEEDPETQ 3360

  Fly  6910 AD-VLRLEGELAD-MRPILDSINQVGPQLCQLSPGEGAATIESIVTRDNRRFDSIVEQIQRKAER 6972
            |: :..||.:::. |||.:|.:..:..||..|...:.|..:::.....|:..:|:.:::.|:|||
 Worm  3361 AELIFLLEEDISQKMRPSVDELTALSNQLQVLCSADKADELQTNTIAMNKLVNSVADRVARRAER 3425

  Fly  6973 LHLSNQRAKEVTGDIDELLEWFREMDTTLREADLPAMEPKLVRAQLQEHRSINDDISSQKGRVRD 7037
            :.:::::::.|..|:..|:|||......:.|...|:::.:::::||:..|..|::.|:.|.:.|:
 Worm  3426 IEMASKQSRAVLDDLQYLIEWFSAARERILEGAPPSLDLEVLKSQLKHQRITNEEASANKVQFRN 3490

  Fly  7038 VTAASKKVLRESPQSENTAT--LREKLDDLKEIVDTVAQLCSERLGILEQALPLSEHFADSHQGL 7100
            |...:|||.|:.....|.|.  :.:.:|:.||:|:.|..||::|...||:||.|.|........|
 Worm  3491 VAGEAKKVARQLGMEGNEANEKISDTVDEGKELVEEVMALCADRTETLERALALMEQLTSQFDEL 3555

  Fly  7101 TAWLD--DMEQQISRLSMPALRPDQITLQQDKNERLLQSIAEHKPLLDKLNKTGEALGALVADDD 7163
            ..|||  |.|.|.|.....|....::....|.||.|.:.:|.::|:::.......:|..::|:|.
 Worm  3556 NKWLDQMDAELQASPSVTTATPAAELREMHDHNEELARMVAAYRPIIEGFKSDVGSLHEVLAEDQ 3620

  Fly  7164 GAKINEILDTDNARYAALRLELRERQQALESALQESSQFSDKLEGMLRALANTVDQVNQLDPLSA 7228
            ...:..:.......|..:|..:|.|..|:::.:..:..|.::||.::..|....|::.:.:.:||
 Worm  3621 APLLESVAGELVQGYEEVREAVRARGHAIDNMMGATIGFGERLETLVANLQGAADRLRENEGISA 3685

  Fly  7229 LPQKIREQIEDNDALMDDLDKRQDAFSAVQRAANDVIAKAGNKADPAVRDIKAKLEKLNNLWNDV 7293
            .|..:..::.:|.::::.|..:|:|:.|:::.|::::|.| .:.|.|..|::.||.:|..||.::
 Worm  3686 DPSVLESRLAENRSIVESLRDKQNAYDALKQTASELLASA-PEGDAAAGDVENKLNRLEKLWKEI 3749

  Fly  7294 QNATKKRGSSLDDILSVAEPFWKQLNSVMKTLKDLEETLSCQEPPAAQPQDIKKQQVALQEIRHE 7358
            :.....||..|:|:|..|:.||.:|:|..|.:.||...|...||....|:.:..||..:.::..|
 Worm  3750 EREAVDRGVLLEDVLDKAKHFWSELDSCQKAVDDLRNRLELVEPATGHPEQLADQQEIMAQVASE 3814

  Fly  7359 IDQTKPEVEQVRRHGSNLMNMCGEPDKPEVKKHIEDLDNAWDNITALYAKREENLIDAMEKAMEF 7423
            :::.:|.:|.:...|..|.:...:.:|..::..:.::...:..||.|:|:::.:||.|||:||.|
 Worm  3815 MERARPRIEALSIAGKQLADYVPDDEKAVIENQVANVRGGFSTITGLFAEKKRDLIAAMEEAMTF 3879

  Fly  7424 HETLQNLLKFLTKAEDKFAHLGAV--GSDIDAVKRQIEQLKSFKDEVDPHMVEVEALNRQAVELT 7486
            |..||.|||:|..||.|...:..|  ...:..:::.:::|.:|||||....|..|.:...|::|.
 Worm  3880 HGDLQELLKWLDMAEQKLLKMSPVEHAKHMTEIEQLLKELHTFKDEVHERGVAKEQVVATALQLA 3944

  Fly  7487 ERTSPEQAASIREPLSVVNRRWEALLRGMVERQKQLEHALLHLGQFQHALNELLVWINKTDSTLD 7551
            ....|..||::|:|::.:|.||..|...:.||:.:||:.:|.:|:....:.:|..|::||.:||.
 Worm  3945 ADAPPHLAATVRQPVADLNTRWSRLNAALAEREHKLENLMLQMGKLASTIAQLTAWMDKTRATLK 4009

  Fly  7552 QLKPIPGDPQLLEVELA--KLKVLANDIQAHQNSVDTLNDAGRQLIETEKGSVEASTTQEKLRKL 7614
            .:.|......|.::|:|  ||.||:|||.|||:||:.:|.|.::.|:| .|:::|.|: :.|:.:
 Worm  4010 DIAPPKNAVNLRDIEIAQCKLVVLSNDIHAHQDSVNAVNRAAQKYIQT-SGALDAETS-DSLKSM 4072

  Fly  7615 NNEWKQLLQKASDRQHELEEALREAHGYIAEVQDILGWLGDVDAVIGASKPVGGLPETATEQLER 7679
            |.:|:.:.:.......::|.|.:||.....||:....||.:.::.:.::||.|||||||..||:.
 Worm  4073 NLKWEDIQKVLESLAFDMEVAKKEAENVGGEVEKWQRWLEETESALLSTKPTGGLPETAEFQLDE 4137

  Fly  7680 FMEVYNELDENRPKVETIQAQGQEYIKRQNQMKVSSSNLQHTLRTLKQRWDAVVSRASDKKIKLE 7744
            |..:..:::.|...:|......::::|.:.|  .:.:.|..|...:|.:|:.|.....|::.||:
 Worm  4138 FKALKLDVEHNASPLEAHLHATEQHLKEEPQ--DADTWLSKTHGAMKTKWNKVKELLVDREKKLQ 4200

  Fly  7745 IALKEATEFHDTLQAFVEWLTQAEKLLSNAEPVSRVLETIQAQMEEHKVLQKDVSTHREAMLLLD 7809
            :|.::|......|....:|:..||:.|::...:||:.:.|:.|:.||:...::|:..:.||....
 Worm  4201 VAYEQAVALESALNDMEDWIIAAERKLTDQPSISRLPDVIEKQLAEHESWMEEVAGRKMAMTKHQ 4265

  Fly  7810 KKGTHLKYFSQKQDVILIKNLLVSVQHRWERVVSKAAERTRALDHGYKEAREFNDAWSGMMQYLQ 7874
            ..|.|::|:.:|:|.|.|||.|||::||.|::..:.|||.:.|.....|...:.|....:..::.
 Worm  4266 ASGVHMQYYCEKKDAIPIKNRLVSLKHRVEKISGRTAERAKQLAVTRDEVATWQDGLHDLEHFIS 4330

  Fly  7875 ETEQVLDQIIEEATASKEPQKIKKYIGKLKETHRQLGAKQSVYDGTMRTGKNLLERAPKGDRPVL 7939
            :   ||.:|..|...:...:|:|..:.::||..|.:.|||:::|.|.:.|..|.|||.:.:...:
 Worm  4331 D---VLVKIAPEPNTTSSLEKLKAKLEEVKEAQRDVTAKQTLFDVTRKRGIGLAERATRSEYKQI 4392

  Fly  7940 DKMLIELKEQWTRVWSKSIDRQRKLEEALLLSGQFSDALGELLDWLKKAKSRLN--ENGPVHGDL 8002
            .....::.::|..:..|..||.|:.|:|:|..|.|.:::.:|..|:.....|..  |:.||..|:
 Worm  4393 SMTNEKMSKKWAEMLKKLRDRLREAEQAVLEGGAFEESMNDLESWVDDELERYQKAEHEPVFADI 4457

  Fly  8003 ETVQGLCEHHKHIEQDLQKRAAQMQGVLKTGRDLERSGNNPEVGRQLDEMQSI----------WE 8057
            :.|:.|.:.......:.:.:...::.|:|....|..||        :||..||          |.
 Worm  4458 DGVRALVDEESRRSAERKTKENGVKTVVKKADALMASG--------VDEKDSIAQAKERLVEKWN 4514

  Fly  8058 EVKSAVAKRGERLQVALVDAEKLNARVQALFDWLDHAEHKLRYAKNAPDDEKVSREMMDIHMDFM 8122
            :|:.|...||..::.|...||:.:|:..||.|||...|.||: |....:.|.|.:||.:....:.
 Worm  4515 QVEEAARHRGNSIKEAEQAAEEFDAKTHALLDWLAVEEQKLK-ASGLDEVEGVKQEMDEAKGRYQ 4578

  Fly  8123 KDLRVREREKTETFEYAEDIINKAYPDAIPIIKNWLSIIQQRWEEVRQWAINRESKLEQHLQSLK 8187
                       |..:..|:|::|..|.|.||::||:.:::.||:||.:....||..|.:..|..|
 Worm  4579 -----------ECLKKGEEILSKCQPAAEPILRNWMRVVEARWKEVSEKVDEREFTLLEQEQKAK 4632

  Fly  8188 DLDDTIEELLAWLSGLEGTLLNLKHEQLP-DEIPPVEKLIEDHKEFMENTARRQNEVDRACKPRQ 8251
            :.::.||: ||..:..:...||...||.| .::..:|:.|.|..........:|.|||.|||
 Worm  4633 EQNEQIEK-LAKFAAQKREELNRMIEQPPAQDLDTMEQNICDFANLDSELREQQPEVDAACK--- 4693

  Fly  8252 LPPGARKPSRSGKTPVFKGSRDQGLNARKGSRITPTRDTPDRDRLPHYGPRFSPSTSGPELEFRS 8316
                                     :|:||:                                |:
 Worm  4694 -------------------------SAKKGA--------------------------------RN 4701

  Fly  8317 PRAKLLWTKWRDVWMLSWERQRLLNDHLLYLKDVERARNFSWDDWRKRFLKYMNHKKSRLTDLFR 8381
            |.|::|.|:|:.:|:.:...|..|::....|::::|...:.|:||::|::::.:|.|:|:.||||
 Worm  4702 PAAEMLSTEWKKLWLDAMGLQSSLDNQKALLEEMKRLEGWKWEDWKERYVEWNDHAKARVNDLFR 4766

  Fly  8382 KMDKDNNGMIPRDVFIDGILNTKFDTSGLEMKAVADLFDRNGEGLIDWQEFIAALRPDWQER--K 8444
            ::|:.:.|.:||.||||||:.:||.||.|||..|||.||: |:|:|:.:|||.|||.|...|  |
 Worm  4767 RIDRLHTGNVPRQVFIDGIIGSKFPTSRLEMAKVADRFDK-GDGMINAKEFINALRFDASNRNAK 4830

  Fly  8445 PANDSDKIHDEVKRLVMLCTCRQKFRVFQVGEGKYRFGDSQKLRLVRILRSTVMVRVGGGWVALD 8509
            |..|::||..|::.....|:|...:::.::.|..|||||:...|:||||||||||||||||.:||
 Worm  4831 PQTDTEKITHEIELQKKTCSCCTPYQIEKISENHYRFGDTHIKRMVRILRSTVMVRVGGGWESLD 4895

  Fly  8510 EFLQKNDPCRAKGRTNI----ELREQFILADGVSQSMAAFTPRRSTPNAAATASSSPHAHNGGSS 8570
            |||.|:||||||||.||    |.|....|     .||.:||..|             |.....::
 Worm  4896 EFLHKHDPCRAKGRLNINMFPEARPIHAL-----DSMRSFTKNR-------------HGKQLPTT 4942

  Fly  8571 NLPPYMSGQGPIIKVRERSVRSIPMSRPSRSSLSASTPDSLSDNEGSHGGPSGRYTPRKVT---- 8631
            ..|      |||:|:||::.||:|||                   |..||.:| ||   ||
 Worm  4943 GTP------GPIMKIREKTDRSVPMS-------------------GGLGGTAG-YT---VTTDSH 4978

  Fly  8632 -YTSTRTGLTPGG---------SRAGSKPNSRPLSRQGSKPPSRHGSTLSLDSTDDHTPSRIPQR 8686
             :|..|....|..         ||.||..||:. |...|..|||..|..|.|:.|..|  |||..
 Worm  4979 RHTDARPSRIPRAPSDMSAGRLSRVGSVSNSKN-SIVDSSTPSRPESRASSDAGDRQT--RIPSL 5040

  Fly  8687 KPSTG 8691
            :...|
 Worm  5041 RARKG 5045

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
shot	NP_725339.1	SAC6	204..>420	CDD:227401	95/225 (42%)
		CH	223..327	CDD:306753	65/105 (62%)
		SPEC	471..689	CDD:238103	46/217 (21%)
		SPEC	690..866	CDD:238103	71/176 (40%)
		SH3	885..922	CDD:327375	14/36 (39%)
		SPEC	1047..1250	CDD:238103	56/206 (27%)
		SPEC	1153..1390	CDD:238103	63/260 (24%)
		PLEC	<1498..1526	CDD:197605	4/27 (15%)
		Plectin	1949..1981	CDD:307019	0/31 (0%)
		DNA_pol3_delta2	<2711..3178	CDD:331068	37/466 (8%)
		DUF4775	3026..3357	CDD:330579	13/330 (4%)
		SMC_N	<4904..5566	CDD:330553	104/663 (16%)
		SPEC	5304..5513	CDD:238103	36/210 (17%)
		SPEC	<5658..5787	CDD:321951	18/128 (14%)
		SPEC	5793..6007	CDD:238103	31/214 (14%)
		SPEC	6011..6220	CDD:238103	16/208 (8%)
		SPEC	6118..6330	CDD:238103	21/211 (10%)
		PRK09039	<6279..6441	CDD:332967	20/161 (12%)
		SPEC	6443..6660	CDD:238103	56/218 (26%)
		SPEC	6663..6878	CDD:238103	56/214 (26%)
		SPEC	6880..7087	CDD:238103	56/214 (26%)
		SPEC	6986..7196	CDD:238103	58/213 (27%)
		SPEC	7196..7417	CDD:238103	55/220 (25%)
		SPEC	7314..7526	CDD:238103	65/213 (31%)
		SPEC	7528..7747	CDD:238103	65/220 (30%)
		SPEC	7749..7968	CDD:238103	61/218 (28%)
		SPEC	7973..8181	CDD:238103	58/219 (26%)
		EF-hand_7	8373..8437	CDD:316058	35/63 (56%)
		GAS2	8450..8522	CDD:128539	39/71 (55%)
		Herpes_ICP4_C	8550..>8795	CDD:332854	44/156 (28%)
vab-10	NP_001335521.1	CH	307..413	CDD:366016	65/105 (62%)
		SPEC	664..758	CDD:197544	20/93 (22%)
		SPEC	760..933	CDD:238103	70/172 (41%)
		SH3_10	935..999	CDD:375415	22/64 (34%)
		SPEC	1115..1329	CDD:351773	57/214 (27%)
		CCDC158	1303..>2083	CDD:318193	265/2550 (10%)
		SMC_prok_B	1730..2520	CDD:274008	306/3268 (9%)
		Smc	<2320..3099	CDD:224117	251/1634 (15%)
		SPEC	2999..3216	CDD:238103	68/216 (31%)
		SPEC	3218..3429	CDD:351773	51/210 (24%)
		SPEC	3434..3653	CDD:238103	59/218 (27%)
		SPEC	3659..3873	CDD:238103	55/214 (26%)
		SPEC	3879..4084	CDD:238103	69/206 (33%)
		SPEC	4103..4308	CDD:238103	62/206 (30%)
		PTZ00121	<4352..>4771	CDD:173412	127/499 (25%)
		SPEC	4427..4626	CDD:238103	58/218 (27%)
		GAS2	4836..4908	CDD:128539	39/71 (55%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	133	1.000	Domainoid score	I3136
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H134369
Inparanoid	1	1.050	1802	1.000	Inparanoid score	I24
Isobase	1	0.950	-	0	Normalized mean entropy	S7584
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D17559at33208
OrthoFinder	1	1.000	-	-		FOG0003564
OrthoInspector	1	1.000	-	-		oto20556
orthoMCL	1	0.900	-	-		OOG6_101076
Panther	1	1.100	-	-	LDO	PTHR23169
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2438
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	13	12.920