DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment shot and si:ch211-39f2.3

DIOPT Version :9

Sequence 1:	NP_725339.1	Gene:	shot / 36542	FlyBaseID:	FBgn0013733	Length:	8805	Species:	Drosophila melanogaster
Sequence 2:	XP_009305155.1	Gene:	si:ch211-39f2.3 / 100330672	ZFINID:	ZDB-GENE-131126-52	Length:	5336	Species:	Danio rerio

Alignment Length:	446	Identity:	97/446 - (21%)
Similarity:	146/446 - (32%)	Gaps:	133/446 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly  3277 DDSTR--TEPTNEIVHEERVVTVEEPTITETTVTTTTITTTTTSSSEETLPQENTATVKETPLNE 3339
            ||||.  |..|..:..||               :||.:||||||     ||.:::.|...|..:.
Zfish  4929 DDSTTYLTTTTENLPAEE---------------STTDMTTTTTS-----LPSDDSTTYLTTTRSN 4973

  Fly  3340 PVPSSPAETKEIEQTTNDDQKKPEEIVDTEKKTTEQK--PVETIPTEPISTSETTTVTLT-TKTT 3401
            ...:......|...|.|:..:|...:.....|....:  |......:...|.|.:..::: ::..
Zfish  4974 LPEAEEDHCSEFNCTENEHCEKKHGVYGCSCKKNHHRSHPSAADSFDFTETCENSHGSISLSRCQ 5038

  Fly  3402 IVDEGKLHPPSDIEQIIQPHSTSDKHQSLVDFI----EQEKGTQPAEGGSNIL-QNVKDAAKLGA 3461
            :.|.|.   ||||..:...:.........|:|.    |...||.....|::|: :|.
Zfish  5039 LFDAGF---PSDILHLNNHNCRGKVRDGQVEFYFDNNEHVCGTSLTANGTHIIYENF-------- 5092

  Fly  3462 LAIVGAPVLAGKALVDALTTEKTLKPEHSTSQVVTET--VEELPTEIITTSTATLVTKVTTTTTT 3524
              |||.|...|..:..|    |.||...|...:.|:|  ::..|.|               :|..
Zfish  5093 --IVGEPNTTGLLVSRA----KALKLSFSCVYLQTQTLSMDINPLE---------------STVH 5136

  Fly  3525 TTTSTSEGTPDDEALDVVKLPAELVE------SSVKREVPRTLAIGDAISQKLISPDECQVIVDG 3583
            .|....:||     ..|..:|.:..|      .||..||.:.:.:              ::.|||
Zfish  5137 KTLPVGQGT-----YRVRMIPYQDAEFMHPFAGSVAAEVSKRIFV--------------EIRVDG 5182

  Fly  3584 EQQSQ---TVSTLLKEEQLSPLDEVQ---IIDDKLIVLQQVSYLVDADTELTPQNLYELNIYDPE 3642
            ...:|   .:.|........|.|.|:   |:|       :.....|...||.            |
Zfish  5183 VDDNQFASVIDTCWATPVNDPHDSVRWDLIVD-------RCPNPNDDTVELV------------E 5228

  Fly  3643 NQYFIDPSTGQKISFHTLVFDMNVFNPETILVKNFSTGKYETLTAALERPLL-DRH 3697
            |    ..||..:.||...:|..|            ||..|  |..|:...|| |.|
Zfish  5229 N----GNSTVSRFSFEMFIFTAN------------STKVY--LHCAIHLCLLTDNH 5266

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
shot	NP_725339.1	SAC6	204..>420	CDD:227401
		CH	223..327	CDD:306753
		SPEC	471..689	CDD:238103
		SPEC	690..866	CDD:238103
		SH3	885..922	CDD:327375
		SPEC	1047..1250	CDD:238103
		SPEC	1153..1390	CDD:238103
		PLEC	<1498..1526	CDD:197605
		Plectin	1949..1981	CDD:307019
		DNA_pol3_delta2	<2711..3178	CDD:331068
		DUF4775	3026..3357	CDD:330579	22/81 (27%)
		SMC_N	<4904..5566	CDD:330553
		SPEC	5304..5513	CDD:238103
		SPEC	<5658..5787	CDD:321951
		SPEC	5793..6007	CDD:238103
		SPEC	6011..6220	CDD:238103
		SPEC	6118..6330	CDD:238103
		PRK09039	<6279..6441	CDD:332967
		SPEC	6443..6660	CDD:238103
		SPEC	6663..6878	CDD:238103
		SPEC	6880..7087	CDD:238103
		SPEC	6986..7196	CDD:238103
		SPEC	7196..7417	CDD:238103
		SPEC	7314..7526	CDD:238103
		SPEC	7528..7747	CDD:238103
		SPEC	7749..7968	CDD:238103
		SPEC	7973..8181	CDD:238103
		EF-hand_7	8373..8437	CDD:316058
		GAS2	8450..8522	CDD:128539
		Herpes_ICP4_C	8550..>8795	CDD:332854
si:ch211-39f2.3	XP_009305155.1	NIDO	2120..2255	CDD:295411
		VWD	2308..2474	CDD:214566
		C8	2518..2591	CDD:214843
		TIL	2595..2648	CDD:280072
		VWC	2650..2703	CDD:302663
		VWD	2710..2864	CDD:278521
		C8	2904..2974	CDD:214843
		TIL	2978..3028	CDD:280072
		VWC	3033..3088	CDD:302663
		VWD	3095..3252	CDD:278521
		C8	3290..3361	CDD:285899
		TIL	3365..3417	CDD:280072
		VWC	3419..3472	CDD:302663
		NIDO	3576..3711	CDD:214712
		VWD	3774..3930	CDD:214566
		C8	3977..4047	CDD:285899
		TIL	4051..4104	CDD:280072
		VWC	4106..4159	CDD:302663
		VWD	4166..4320	CDD:278521
		C8	4360..4430	CDD:214843
		TIL	4434..4487	CDD:280072
		VWC	4489..4544	CDD:302663
		VWD	4551..4708	CDD:278521
		C8	4746..4817	CDD:285899
		TIL	4821..4873	CDD:280072
		ZP	5024..5273	CDD:214579	71/331 (21%)
		Zona_pellucida	5153..5271	CDD:278526	35/165 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1216
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900