Protein Alignment CG13344 and RNF25

DIOPT Version :10

• Sequence 1: NP_610915.2
• Gene: CG13344 / 36541
• FlyBaseID: FBgn0033884
• Length: 374
• Species: Drosophila melanogaster
• Sequence 2: NP_071898.2
• Gene: RNF25 / 64320
• HGNCID: 14662
• Length: 459
• Species: Homo sapiens
• Alignment Length: 350
• Identity: 109/350 - (31%)
• Similarity: 174/350 - (49%)
• Gaps: 37/350 - (10%)

  Fly     4 LQDEVESLEAILMDDV-CIKRTPSGEVEQIETTVLPLTGEEEEQQYVCVTLQVHPTPGYPEESPT 67
            |..|||.||:|.:|:: .||........:|..|:.|.|.|:::.||||.||.:.....||.|.|.
Human    16 LPSEVEVLESIYLDELQVIKGNGRTSPWEIYITLHPATAEDQDSQYVCFTLVLQVPAEYPHEVPQ 80

  Fly    68 FKLLRPRGLDDARLEAIRSACNAKIKESIGFPVVFDLIEVVREHLSGSNLPSGQCVVCLYGFADG 132
            ..:..||||.|.::..|........|..:|..::::|||..:|.|:.:|:|.||||:|||||.:.
Human    81 ISIRNPRGLSDEQIHTILQVLGHVAKAGLGTAMLYELIEKGKEILTDNNIPHGQCVICLYGFQEK 145

  Fly   133 DEFTRTECFHYLHSYCLARHLNALR-----RNYQEEFDKLPAWLQKTADPFQALCPVCREHIGDE 192
            :.||:|.|:||.|.:||||::..:.     :..::|.::..|..::.|...|  ||||||.:..:
Human   146 EAFTKTPCYHYFHCHCLARYIQHMEQELKAQGQEQEQERQHATTKQKAVGVQ--CPVCREPLVYD 208

  Fly   193 TDSLKCAMPPSELLNAPEFKVTEELRQMQQRMSELYLQQKSRGAIIDVNAEGSA-VISI------ 250
            ..|||.|..|.:.:...: ...|.|||.::| ..||.:|:.||.|||:.||.:. .||:
Human   209 LASLKAAPEPQQPMELYQ-PSAESLRQQEER-KRLYQRQQERGGIIDLEAERNRYFISLQQPPAP 271

  Fly   251 ---ETEEDIRRRRRREEAEAAKKLEGPSKEEVIKPTTSSTFAPVVQ-------------ETHRIM 299
               |:..|:.:..:.....||:....|:.:..:.|........:.:             ||.:.|
Human   272 AEPESAVDVSKGSQPPSTLAAELSTSPAVQSTLPPPLPVATQHICEKIPGTRSNQQRLGETQKAM 336

  Fly   300 ---PEPTNNNYHH-NRRHYRGGRRH 320
               |:|:...:.. .|||.:||..|
Human   337 LDPPKPSRGPWRQPERRHPKGGECH 361

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13344	NP_610915.2	RWD_RNF25	4..113	CDD:467654	37/109 (34%)
		RING-H2_RNF25	118..189	CDD:438133	31/75 (41%)
RNF25	NP_071898.2	RWD_RNF25	16..126	CDD:467654	37/109 (34%)
		RING-H2_RNF25	131..205	CDD:438133	31/75 (41%)
		PHA03247	<264..445	CDD:223021	17/97 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	268..309		6/40 (15%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	322..459		10/39 (26%)