Protein Alignment CG16935 and RTN4IP1

DIOPT Version :10

• Sequence 1: NP_610914.2
• Gene: CG16935 / 36540
• FlyBaseID: FBgn0033883
• Length: 357
• Species: Drosophila melanogaster
• Sequence 2: NP_116119.2
• Gene: RTN4IP1 / 84816
• HGNCID: 18647
• Length: 396
• Species: Homo sapiens
• Alignment Length: 378
• Identity: 87/378 - (23%)
• Similarity: 144/378 - (38%)
• Gaps: 100/378 - (26%)

  Fly    20 SVVAKSLKYTQHGEPQEVLQLVEDKL------PDPKDNQVLVKILAAPINPADINTIQG------ 72
            |.|..:....::|: .|||:..::.:      |    |:|:||:.||.:||.|:|...|
Human    40 STVMPAWVIDKYGK-NEVLRFTQNMMMPIIHYP----NEVIVKVHAASVNPIDVNMRSGYGATAL 99

  Fly    73 ---KYPVKPK-----FPAVGGNECVAEVICVGDKVKGFEAGQHVIPLASGLGTWTTHAVYKE--- 126
               :.|:..|     ||...|.:....|:..|..||.|:.|..|         |.....:|:
Human   100 NMKRDPLHVKIKGEEFPLTLGRDVSGVVMECGLDVKYFKPGDEV---------WAAVPPWKQGTL 155

  Fly   127 DQLLIVS--------KKVGLAEAATSTVNPTTAYRMLKDFVQL----CPGDTVIQNGANSAVGQA 179
            .:.::||        |.:...:||:......||:..:.....|    |.|..|:..||:..||..
Human   156 SEFVVVSGNEVSHKPKSLTHTQAASLPYVALTAWSAINKVGGLNDKNCTGKRVLILGASGGVGTF 220

  Fly   180 VHQLCRAWGINSVGIVRDRPEIAELKQMLQCLGATEVLTEAEIRTSDIFKSGKLK------KP-R 237
            ..|:.:||..:...:...     :..::::.|||.:|:.         :|||.::      || .
Human   221 AIQVMKAWDAHVTAVCSQ-----DASELVRKLGADDVID---------YKSGSVEEQLKSLKPFD 271

  Fly   238 LAFNCVGGKSATEVSRHLD--NGGVLVTY--------------GGMSREPVTVATGPLIFKDIAF 286
            ...:.|||.:.|.....|.  :|...||.              .||.:..|||.:.       |.
Human   272 FILDNVGGSTETWAPDFLKKWSGATYVTLVTPFLLNMDRLGIADGMLQTGVTVGSK-------AL 329

  Fly   287 RGFWM---TRWSKENYSSPERSKMFKEIFELMEQGKFVAPNHEMVPLAKFKDA 336
            :.||.   .||:....|.|    ...:|.||::.||......:..|.:|..:|
Human   330 KHFWKGVHYRWAFFMASGP----CLDDIAELVDAGKIRPVIEQTFPFSKVPEA 378

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG16935	NP_610914.2	ETR	23..355	CDD:176250	85/375 (23%)
RTN4IP1	NP_116119.2	RTN4I1	43..394	CDD:176210	85/375 (23%)