| Sequence 1: | NP_610913.1 | Gene: | Uba3 / 36539 | FlyBaseID: | FBgn0263697 | Length: | 450 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_003959.3 | Gene: | UBA3 / 9039 | HGNCID: | 12470 | Length: | 463 | Species: | Homo sapiens |
| Alignment Length: | 431 | Identity: | 277/431 - (64%) |
|---|---|---|---|
| Similarity: | 344/431 - (79%) | Gaps: | 6/431 - (1%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 16 RFNGLRNILEREGPFCKDGFAASSENLEFLQTKCQVLIIGAGGLGCELLKDLALMGFGNLHVIDM 80
Fly 81 DTIELSNLNRQFLFRRTDIGASKAECAARFINARVPTCRVTPHFKKIQDFDESFYQQFHLVVCGL 145
Fly 146 DSIVARRWINGMLLSMLRYEEDGTIDTSSIVPMIDGGTEGFKGNARVILPGFTACIECTLDLFPP 210
Fly 211 QVNYPLCTIANTPRLPEHCIEYVKIIQWEKQNPF--GVPLDGDDPQHIGWIYERALERSNEFNIT 273
Fly 274 GVTYRLVQGVVKHIIPAVASTNAAIAAACALEVFKLATSCYDSMANYLNFNDLDGIYTYTYEAEK 338
Fly 339 SENCLACSNTPQPLPIEDPNTTTLEDVIKLLCDSPRFQLKSPALTTVMKDGKRRTLYMSGVKSIE 403
Fly 404 EATRKNLTQSLGELGLHDGQQLTVTDATSPSAMTLQLKYQS 444 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Uba3 | NP_610913.1 | ThiF | 48..>220 | CDD:279270 | 129/171 (75%) |
| Uba3_RUB | 50..346 | CDD:238765 | 217/297 (73%) | ||
| E2_bind | 357..442 | CDD:285976 | 39/84 (46%) | ||
| UBA3 | NP_003959.3 | Interaction with UBE2M N-terminus | 53..70 | 6/16 (38%) | |
| Uba3_RUB | 71..368 | CDD:238765 | 217/297 (73%) | ||
| Interaction with UBE2M N-terminus | 157..161 | 2/3 (67%) | |||
| Interaction with UBE2M N-terminus | 192..217 | 22/24 (92%) | |||
| Interaction with NEDD8 | 227..229 | 1/1 (100%) | |||
| Interaction with NAE1. /evidence=ECO:0000269|PubMed:12740388 | 242..248 | 4/5 (80%) | |||
| Interaction with NAE1. /evidence=ECO:0000269|PubMed:12740388 | 292..295 | 1/2 (50%) | |||
| Interaction with UBE2M N-terminus | 331..338 | 4/6 (67%) | |||
| Interaction with NEDD8 | 352..357 | 4/4 (100%) | |||
| Interaction with UBE2M core domain | 368..463 | 43/97 (44%) | |||
| E2_bind | 376..461 | CDD:400951 | 39/85 (46%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 1 | 0.930 | - | - | C165159764 | |
| Domainoid | 1 | 1.000 | 468 | 1.000 | Domainoid score | I460 |
| eggNOG | 1 | 0.900 | - | - | E1_COG0476 | |
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 1 | 1.000 | - | - | H2951 | |
| Inparanoid | 1 | 1.050 | 573 | 1.000 | Inparanoid score | I1046 |
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 1 | 1.010 | - | - | QHG54659 | |
| OrthoDB | 1 | 1.010 | - | - | D256073at33208 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0005107 | |
| OrthoInspector | 1 | 1.000 | - | - | oto91829 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_101845 | |
| Panther | 1 | 1.100 | - | - | LDO | PTHR10953 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R1578 |
| SonicParanoid | 1 | 1.000 | - | - | X3628 | |
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 1 | 0.960 | - | - | ||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 16 | 15.800 | |||||