Protein Alignment Uba3 and UBA2

DIOPT Version :10

• Sequence 1: NP_610913.1
• Gene: Uba3 / 36539
• FlyBaseID: FBgn0263697
• Length: 450
• Species: Drosophila melanogaster
• Sequence 2: NP_010678.3
• Gene: UBA2 / 851998
• SGDID: S000002798
• Length: 636
• Species: Saccharomyces cerevisiae
• Alignment Length: 531
• Identity: 129/531 - (24%)
• Similarity: 202/531 - (38%)
• Gaps: 186/531 - (35%)

  Fly    47 TKCQVLIIGAGGLGCELLKDLALMGFGNLHVIDMDTIELSNLNRQFLFRRTDIGASKAECAARFI 111
            ::|  |::||||:|.|||||:.||.||.:|::|:|||:|||||||||||:.||...|:..|.:.:
Yeast    22 SRC--LLVGAGGIGSELLKDIILMEFGEIHIVDLDTIDLSNLNRQFLFRQKDIKQPKSTTAVKAV 84

  Fly   112 NARVPTCRVTPHFKKIQD---FDESFYQQFHLVVCGLDSIVARRWIN--GMLLSMLRYEEDGTID 171
            . .....::.|:...:.|   |...:::||.::...||::.|||::|  ...||:
Yeast    85 Q-HFNNSKLVPYQGNVMDISTFPLHWFEQFDIIFNALDNLAARRYVNKISQFLSL---------- 138

  Fly   172 TSSIVPMIDGGTEGFKGNARVILPGFTACIECTLDLFPPQVNYPLCTIANTPRLPEHCI------ 230
                 |:|:.||.||.|..:.|:||.|.|.|||....|.  .:|:|||.:||..|.|||
Yeast   139 -----PLIESGTAGFDGYMQPIIPGKTECFECTKKETPK--TFPVCTIRSTPSQPIHCIVWAKNF 196

  Fly   231 --------------------------EYVKIIQWE------------------------------ 239
                                      |.:|.|:.|
Yeast   197 LFNQLFASETSGNEDDNNQDWGTDDAEEIKRIKQETNELYELQKIIISRDASRIPEILNKLFIQD 261

  Fly   240 -----------KQNPFGVPL--------------------------------------------- 248
                       |.....|||
Yeast   262 INKLLAIENLWKTRTKPVPLSDSQINTPTKTAQSASNSVGTIQEQISNFINITQKLMDRYPKEQN 326

  Fly   249 ----DGDDPQHIGWIYERALERSNEFNITGVTYRLVQGVVKHIIPAVASTNAAIAAA---CALEV 306
                |.||...:.::...|..||:.|||...:...::.:..:||||:|:|||.:|.|   .:|.|
Yeast   327 HIEFDKDDADTLEFVATAANIRSHIFNIPMKSVFDIKQIAGNIIPAIATTNAIVAGASSLISLRV 391

  Fly   307 FKLATSCYDSMANYLNFNDLDGIYTYTYEAEK---------------SENCLACSNTPQ---PLP 353
            ..|..  |.....|.:.|     ..:|.:|..               ::||..||...:   .|.
Yeast   392 LNLLK--YAPTTKYTDLN-----MAFTAKASNLSQNRYLSNPKLAPPNKNCPVCSKVCRGVIKLS 449

  Fly   354 IEDPNTTTLEDVIKLLCDSPRFQLKSPALTTVMKDGKRRTLYMSGVKSIEEATRKNLTQSLGELG 418
            .:..|...|.|.:.|:    |.:...|...:::....:|.|:....:.:.:.|       |.|:.
Yeast   450 SDCLNKMKLSDFVVLI----REKYSYPQDISLLDASNQRLLFDYDFEDLNDRT-------LSEIN 503

  Fly   419 LHDGQQLTVTD 429
            |.:|..:..:|
Yeast   504 LGNGSIILFSD 514

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Uba3	NP_610913.1	Uba3_RUB	50..346	CDD:238765	111/440 (25%)
		E2_bind	357..442	CDD:462611	14/73 (19%)
UBA2	NP_010678.3	Uba2_SUMO	23..438	CDD:238766	112/441 (25%)
		UBA_E1_SCCH	183..>370	CDD:463157	22/186 (12%)
		UAE_UbL	453..518	CDD:476859	14/73 (19%)