Protein Alignment Uba3 and Uba7

DIOPT Version :9

• Sequence 1: NP_610913.1
• Gene: Uba3 / 36539
• FlyBaseID: FBgn0263697
• Length: 450
• Species: Drosophila melanogaster
• Sequence 2: NP_076227.1
• Gene: Uba7 / 74153
• MGIID: 1349462
• Length: 977
• Species: Mus musculus
• Alignment Length: 578
• Identity: 123/578 - (21%)
• Similarity: 194/578 - (33%)
• Gaps: 212/578 - (36%)

  Fly    52 LIIGAGGLGCELLKDLALMGF-----GNLHVIDMDTIELSNLNRQFLFRRTDIGASKAECAARFI 111
            |::|||.:|||:||..||:|.     |.:.|.|||.||.|||:||||||..|:...|||.||...
Mouse   423 LLVGAGAIGCEMLKVFALVGLGVRANGGVTVADMDYIERSNLSRQFLFRPKDVRRPKAEVAAAAA 487

  Fly   112 NARVPTCRVTPHFKKIQD-----FDESFYQQFHLVVCGLDSIVARRWINGMLLSMLRYEEDGTID 171
            :...|..|.||:...:..     :|:||:.:.:.||..|||..||.::.......|:
Mouse   488 HRLNPDLRATPYTCPLDPTTEDIYDDSFFSRVNGVVAALDSFQARHYVAARCTHYLK-------- 544

  Fly   172 TSSIVPMIDGGTEGFKGNARVILPGFTACIE-CTLDLFPPQVNYPLCTIANTPRLPEHCIEYVK- 234
                 |:::.||:|..|:|.|.:|..|.... ...|.......||:||:.:.|...||.:::.:
Mouse   545 -----PLLEAGTQGTWGSASVFVPYVTEAYRGPASDAASEDAPYPVCTLRHIPSSMEHSVQWAQD 604

  Fly   235 ---------------------------------IIQ-----------------------WE---- 239
                                             ::|                       |:
Mouse   605 QFEGLFRLSTETINCYQQTCTSLSATDRTETLALLQQVMGVLRTRPQTWQDCVVWALGHWQLCFH 669

  Fly   240 ----------------------------------------------------------------- 239
                                                                             
Mouse   670 DKVLEGGTQFSSGSNKCPHPLQFDPNHDMHFLYVLAAANLYARMHGLPGSQSQPALRELLTRLLE 734

  Fly   240 ----KQNPF---------------------GVPL-------DGDDPQHIGWIYERALERSNEFNI 272
                .||.|                     |.||       |.|...|:.::......|...:.|
Mouse   735 SDSRPQNLFSAEHGQEQLKELQETLDDWRKGPPLKPVLFVKDDDSNFHVDFVVAATDLRCQNYGI 799

  Fly   273 TGVTYRLVQGVVKHIIPAVASTNAAIAAACALEVFKLATSCYDSMANYLNFNDLDGIYTYTYEAE 337
            ..|.:..::.:|..||||:|::.|.:|....||::|:.:    .:.::..|.     ::|.:.||
Mouse   800 LPVNHARIKQIVGRIIPAIATSTAVVAGLLGLELYKVVS----GLRSHGTFR-----HSYLHLAE 855

  Fly   338 KSENCLACSNTPQPLPIEDPNTTTLEDVIKLLCDSPRFQLKS--------PALTTVMKDGKRRTL 394
             :....:..:.|......|...|.. |.:|:....|...|||        ..|...|....:..|
Mouse   856 -NHFIRSAPSAPAVQSFRDLKWTCW-DRLKVPAVQPERTLKSLLAHLQEEHGLKVEMLLHHQALL 918

  Fly   395 YMSGVKSIEEATRKNLTQSLGELGLHDGQQLTVTD-ATSP--SAMTLQLKYQSNEVEM 449
            |.||..|.::|  ::|...:.||..|      ||. ...|  ..:..:|..:..|.||
Mouse   919 YSSGWSSEKQA--QHLCLRVTELVQH------VTGWKPKPGLKVLVFELSCEGEEEEM 968

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Uba3	NP_610913.1	ThiF	48..>220	CDD:279270	63/178 (35%)
		Uba3_RUB	50..346	CDD:238765	95/462 (21%)
		E2_bind	357..442	CDD:285976	23/95 (24%)
Uba7	NP_076227.1	Ube1	1..961	CDD:273603	120/569 (21%)
		Ube1_repeat1	5..386	CDD:238768
		E1_4HB	254..317	CDD:292809
		E1_enzyme_family	421..932	CDD:304554	112/534 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0476
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810