DRSC/TRiP Functional Genomics Resources

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Protein Alignment Uba3 and Mocs3

DIOPT Version :10

Sequence 1:NP_610913.1 Gene:Uba3 / 36539 FlyBaseID:FBgn0263697 Length:450 Species:Drosophila melanogaster
Sequence 2:NP_001153802.1 Gene:Mocs3 / 69372 MGIID:1916622 Length:460 Species:Mus musculus


Alignment Length:302 Identity:68/302 - (22%)
Similarity:96/302 - (31%) Gaps:114/302 - (37%)


- Green bases have known domain annotations that are detailed below.


  Fly    18 DGRVFQIEYAAKAVENSGTVIGLRGKDGVVLAVEKLITSKL--YEPDCGTRIFTIDTSIGMA--- 77
            :||||      ||..|            ::.|......:.|  |..|.|.|..|....|..|   
Mouse    31 EGRVF------KAHRN------------ILFASSGYFRALLVHYLQDNGQRHSTASLDIVTAEAF 77

  Fly    78 --ISGMITDGRA------VVDIARQEAASYRQQN-----------------NRPIPLKQLNDRLS 117
              |...:..||.      |::|  ..||||.|..                 ||.|...:..|.|.
Mouse    78 SFILDFLYSGRLDLRSDNVIEI--MSAASYLQMTDVVNFCKGYIKSSLEICNREIERLRERDGLD 140

  Fly   118 SYFHAYTLYSAVRPFGVSVI-LASWSE--------------EKGPEMYMIDPSGVSCVSLSQKQT 167
                     ::..|..|:.. :||.||              :..|...:..|:..|    |:...
Mouse   141 ---------NSATPVSVTCTPVASTSEADQRTCQVTEALSPDDAPTAAVCTPANTS----SKDSE 192

  Fly   168 GESSTTLATIVMYYYFQGYFGCAVGKAKQTAKTEIE-KLKLSDMSVKDLV--LTAGKIIYQVHDE 229
            .|:|            ||.|         ...|.|. .||:|  ...|||  .|.|.::..||.:
Mouse   193 SENS------------QGAF---------PNHTPINAPLKVS--PGPDLVNSSTPGLLLGLVHPK 234

  Fly   230 LK-DKDFKLELSWVCQDSNGIHKTVPAEVYAAANRAGQEAVD 270
            :: |.|.:.|.|...:|         |.:|...|..|:..|:
Mouse   235 IEYDPDEEGESSRESKD---------AALYQGPNHDGERTVN 267

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Uba3NP_610913.1 Uba3_RUB 50..346 CDD:238765 60/270 (22%)
E2_bind 357..442 CDD:462611
Mocs3NP_001153802.1 PRK07411 56..460 CDD:180967 59/259 (23%)
Interaction with NFS1. /evidence=ECO:0000250|UniProtKB:O95396 158..238 22/106 (21%)
Blue background indicates that the domain is not in the aligned region.

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