DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Uba3 and Aos1

DIOPT Version :9

Sequence 1:	NP_610913.1	Gene:	Uba3 / 36539	FlyBaseID:	FBgn0263697	Length:	450	Species:	Drosophila melanogaster
Sequence 2:	NP_650198.1	Gene:	Aos1 / 41532	FlyBaseID:	FBgn0029512	Length:	337	Species:	Drosophila melanogaster

Alignment Length:	325	Identity:	65/325 - (20%)
Similarity:	120/325 - (36%)	Gaps:	99/325 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 ENLEFLQTKCQVLIIGAGGLGCELLKDLALMGFGNLHVIDMDTIELSNLNRQFLFRRTDIGASKA 104
            |:.:.|:| .::||.|..|||.|:.|::.|.|..::.::|...:...:...|||..|..:..::|
  Fly    32 ESQKRLRT-AKILIAGLCGLGAEITKNIILSGVNSVKLLDDKDVTEEDFCSQFLVPRESLNTNRA 95

  Fly   105 ECAARFINARVPTCRVTPHFKKIQDFDESFYQQFHLVVCGLDSIVARRWINGMLLSMLRYEEDGT 169
            |.:.....|..|...::...:.:::....|:.||.:||           :||     ...||...
  Fly    96 EASLTRARALNPMVDISADREPLKEKTSEFFGQFDVVV-----------VNG-----ATNEELLR 144

  Fly   170 IDT------SSIVPMIDGGTEGFKGNARVILPGFTACIECTLDLFPPQVNYPLCTIANTPRLPEH 228
            |||      ...:.....||.||          :.|.::        :.:|           .|.
  Fly   145 IDTICRDLGVKFIATDVWGTFGF----------YFASLQ--------KHSY-----------VED 180

  Fly   229 CIEYVKIIQWEKQNPF---GVPL--DGDDPQHIGWI--------YERALERS----------NEF 270
            .|::..:...||:..:   .:|.  |.|.|.:..|:        |.|.|:|:          .:|
  Fly   181 VIKHKVVANSEKKKKYETVSIPTQRDVDYPGYSAWLDFDVTEPSYLRKLKRNGPGVLLLSVLQKF 245

  Fly   271 NIT---GVTYR-------LVQGVVKHIIP--------------AVASTNAAIAAACALEVFKLAT 311
            ..|   ..:|:       |::|:...::|              .::...|.:....|.||.|:.|
  Fly   246 RTTHKRDPSYKTREADLELLRGIRDELLPNSILGDEALGLIFAQISPAVAVVGGVVAQEVIKVVT 310

Fly 312 311
Fly 311 310

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Uba3	NP_610913.1	ThiF	48..>220	CDD:279270	37/177 (21%)
		Uba3_RUB	50..346	CDD:238765	62/315 (20%)
		E2_bind	357..442	CDD:285976
Aos1	NP_650198.1	Aos1_SUMO	19..>172	CDD:238769	39/166 (23%)
Aos1	NP_650198.1	ThiF	22..>167	CDD:279270	36/151 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45446845
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0476
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10953
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840