DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Uba3 and mocs3

DIOPT Version :9

Sequence 1:	NP_610913.1	Gene:	Uba3 / 36539	FlyBaseID:	FBgn0263697	Length:	450	Species:	Drosophila melanogaster
Sequence 2:	NP_956421.1	Gene:	mocs3 / 393095	ZFINID:	ZDB-GENE-040426-782	Length:	459	Species:	Danio rerio

Alignment Length:	318	Identity:	73/318 - (22%)
Similarity:	108/318 - (33%)	Gaps:	95/318 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    51 VLIIGAGGLGCELLKDLALMGFGNLHVIDMDTIELSNLNRQFLFRRTDIGASKAECAARFINARV 115
            ||::|.|||||.|.:.||..|.|.|.::|.|.:|||||:||.|......|..||..||:.|:...
Zfish    85 VLVVGCGGLGCPLAQYLAAAGIGRLGLLDYDVVELSNLHRQVLHTELTQGQPKALSAAQAISRMN 149

  Fly   116 PTCRVTP-HFKKIQDFDESFYQQFHLVVCGLDSIVARRWINGMLLSMLRYEEDGTIDTSSIVPMI 179
            .|.:..| |.:..::......||:.:|....|::..|..:|           |..:.||.  |::
Zfish   150 STVQCVPYHLQLSRENAIQLIQQYDIVADCSDNVPTRYLVN-----------DACVLTSR--PLV 201

  Fly   180 DGGTEGFKGNARVILPGFTACIECTLDLFPPQVNYPLCTIANTPRLPEHCIEYVKIIQWEKQNPF 244
            .......:|...|.......|..|...:.||            |....:|.:
Zfish   202 SASALRMEGQLTVYNYRGGPCYRCLYPIPPP------------PETVTNCSD------------- 241

  Fly   245 GVPLDGDDPQHIGWIYERALERSNEFNITGVTYRLVQGVVKHIIPAVASTNAAIAAACALEVFKL 309
                                                 |.|..::|.:      :....||||.|:
Zfish   242 -------------------------------------GGVLGVVPGI------MGCLQALEVLKI 263

  Fly   310 ATSCYDSMANYLNFNDLDGIYTYTYE---AEKSENCLACSNTPQPLPIEDPNTTTLED 364
            |:....|.|..|..  .||..|....   ..:.:.|:.|.        |.|..|.|:|
Zfish   264 ASGQECSFAQQLLM--FDGEQTRFRSIRLRSRQKECVVCG--------EKPTITELQD 311

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Uba3	NP_610913.1	ThiF	48..>220	CDD:279270	49/169 (29%)
		Uba3_RUB	50..346	CDD:238765	67/298 (22%)
		E2_bind	357..442	CDD:285976	4/8 (50%)
mocs3	NP_956421.1	PRK07411	46..459	CDD:180967	73/318 (23%)
		ThiF_MoeB_HesA_family	62..290	CDD:238386	66/287 (23%)
		RHOD_ThiF	327..459	CDD:238784
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0476
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810