DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Uba3 and Atg7

DIOPT Version :9

Sequence 1:	NP_610913.1	Gene:	Uba3 / 36539	FlyBaseID:	FBgn0263697	Length:	450	Species:	Drosophila melanogaster
Sequence 2:	NP_611350.1	Gene:	Atg7 / 37141	FlyBaseID:	FBgn0034366	Length:	684	Species:	Drosophila melanogaster

Alignment Length:	144	Identity:	42/144 - (29%)
Similarity:	59/144 - (40%)	Gaps:	33/144 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 NLEFL-QTKCQVLIIGAGGLGCELLKDLALMGFGNLHVIDMDTIELSNLNRQFLFRRTDIGAS-- 102
            |||.: ||||  |:.|||.|||.:.::|...||.::.::|...:..||..||.|:...|..|.
  Fly   333 NLEIISQTKC--LLFGAGTLGCAVARNLLSWGFKHITLLDSGKVGFSNPVRQNLYTHADAVAGNR 395

  Fly   103 -KAECAA---RFINARVPT-------------------CRVTPHFKKIQDFDESFYQQFHLVVCG 144
             ||..||   :.||....|                   .:...|.|.|:..     .|.|.|:..
  Fly   396 MKATTAAQRLKEINPSAETAGYVLEIPMPGHTIGESLLAQTKEHLKVIEKL-----VQDHDVIFL 455

  Fly   145 LDSIVARRWINGML 158
            |......||:..:|
  Fly   456 LTDSRESRWLPTLL 469

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Uba3	NP_610913.1	ThiF	48..>220	CDD:279270	37/136 (27%)
		Uba3_RUB	50..346	CDD:238765	35/134 (26%)
		E2_bind	357..442	CDD:285976
Atg7	NP_611350.1	ATG7_N	9..303	CDD:293029
		E1_like_apg7	11..682	CDD:273590	42/144 (29%)
		Apg7	341..658	CDD:238763	37/136 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45446860
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0476
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10953
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.930