DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Uba3 and Uba1

DIOPT Version :9

Sequence 1:	NP_610913.1	Gene:	Uba3 / 36539	FlyBaseID:	FBgn0263697	Length:	450	Species:	Drosophila melanogaster
Sequence 2:	NP_001014102.1	Gene:	Uba1 / 314432	RGDID:	1359327	Length:	1058	Species:	Rattus norvegicus

Alignment Length:	258	Identity:	77/258 - (29%)
Similarity:	126/258 - (48%)	Gaps:	47/258 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 LEREGPFCKDG-FAASSENLEFLQTKCQVLIIGAGGLGCELLKDLALMGF-----GNLHVIDMDT 82
            |.|:..:  || .|....:|:....|.:..::|||.:||||||:.|::|.     |.:.|.||||
  Rat   445 LPRQNRY--DGQVAVFGSDLQEKLGKQKYFLVGAGAIGCELLKNFAMIGLGCGEGGEVVVTDMDT 507

  Fly    83 IELSNLNRQFLFRRTDIGASKAECAARFINARVPTCRVTPHFKKI-----QDFDESFYQQFHLVV 142
            ||.||||||||||..|:...|::.||..:....|..:||.|..::     :.:|:.|:|....|.
  Rat   508 IEKSNLNRQFLFRPWDVTKLKSDTAAAAVRQMNPYIQVTSHQNRVGPDTERIYDDDFFQNLDGVA 572

  Fly   143 CGLDSIVARRWINGMLLSMLRYEEDGTIDTSSIVPMIDGGTEGFKGNARVILPGFTACIECTLDL 207
            ..||::.||.:::...:...:             |:::.||.|.|||.:|::|..|.....:.|
  Rat   573 NALDNVDARMYMDRRCVYYRK-------------PLLESGTLGTKGNVQVVIPFLTESYSSSQD- 623

  Fly   208 FPPQVNYPLCTIANTPRLPEHCIEYVKIIQWEKQNPFGVPLDGDDPQHIGWIYERALERSNEF 270
             ||:.:.|:||:.|.|...||      .:||.:....|             ::::..|..|::
  Rat   624 -PPEKSIPICTLKNFPNAIEH------TLQWARDEFEG-------------LFKQPAENVNQY 666

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Uba3	NP_610913.1	ThiF	48..>220	CDD:279270	62/181 (34%)
		Uba3_RUB	50..346	CDD:238765	70/231 (30%)
		E2_bind	357..442	CDD:285976
Uba1	NP_001014102.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..46
		Ube1	49..1055	CDD:273603	77/258 (30%)
		2 approximate repeats. /evidence=ECO:0000255	63..611		60/180 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0476
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810