Protein Alignment Uba3 and Uba2

DIOPT Version :9

• Sequence 1: NP_610913.1
• Gene: Uba3 / 36539
• FlyBaseID: FBgn0263697
• Length: 450
• Species: Drosophila melanogaster
• Sequence 2: NP_001094049.1
• Gene: Uba2 / 308508
• RGDID: 1312023
• Length: 639
• Species: Rattus norvegicus
• Alignment Length: 564
• Identity: 136/564 - (24%)
• Similarity: 211/564 - (37%)
• Gaps: 199/564 - (35%)

  Fly    50 QVLIIGAGGLGCELLKDLALMGFGNLHVIDMDTIELSNLNRQFLFRRTDIGASKAECAARFINAR 114
            :||::||||:||||||:|.|.||.::.:||:|||::|||||||||::..:|.|||:.|...:...
  Rat    19 RVLVVGAGGIGCELLKNLVLTGFSHIDLIDLDTIDVSNLNRQFLFQKKHVGRSKAQVAKESVLQF 83

  Fly   115 VPTCRVTPHFKKIQ--DFDESFYQQFHLVVCGLDSIVARRWINGMLLSMLRYEEDGTIDTSSIVP 177
            .|...:..|...|.  |::..|::||.||:..||:..||..:|.|.|             ::.||
  Rat    84 HPQANIEAHHDSIMNPDYNVEFFRQFILVMNALDNRAARNHVNRMCL-------------AADVP 135

  Fly   178 MIDGGTEGFKGNARVILPGFTACIECTLDLFPPQVNYPLCTIANTPRLPEHCIEYVKII------ 236
            :|:.||.|:.|....|..|.|.|.||...  |.|..:|.|||.|||..|.|||.:.|.:
  Rat   136 LIESGTAGYLGQVTTIKKGVTECYECHPK--PTQRTFPGCTIRNTPSEPIHCIVWAKYLFNQLFG 198

  Fly   237 ----------------------------------------------------------------- 236
                                                                             
  Rat   199 EEDADQEVSPDRADPEAAWEPTEAEARARASNEDGDIKRISTKEWAKSTGYDPVKLFTKLFKDDI 263

  Fly   237 --------QWEKQNPFGVPL--------------------------------------------- 248
                    .|.|:.| .|||
  Rat   264 RYLLTMDKLWRKRKP-PVPLDWAEVQSQGEEANADQQSEPQLGLKDQQVLDVKSYASLFSKSIET 327

  Fly   249 ----------------DGDDPQHIGWIYERALERSNEFNITGVTYRLVQGVVKHIIPAVASTNAA 297
                            |.|||..:.::...|..|.:.|::...:...::.:..:||||:|:|||.
  Rat   328 LRVRLAEKGDGAELIWDKDDPPAMDFVTSAANLRMHIFSMNMKSRFDIKSMAGNIIPAIATTNAV 392

  Fly   298 IAAACALEVFKLATSCYDSMAN-YLNFND-----------LDGIYTYTYEAEKSENCLACSNTPQ 350
            ||....||..|:.:...|.... :||...           ||         ..:.||..|::.|:
  Rat   393 IAGLIVLEGLKILSGKIDQCRTIFLNKQPNPRKKLLVPCALD---------PPNTNCYVCASKPE 448

  Fly   351 ---PLPIEDPNTTTLED-VIKLLCDSPRFQLKSPALTTVMKDGKRRTLYMSGVKSIEEATRKNLT 411
               .|.:......||:| ::|     .:|.:.:|.:.  ::|||...|    :.|.|..|..|..
  Rat   449 VTVRLNVHKVTVLTLQDKIVK-----EKFAMVAPDVQ--IEDGKGTIL----ISSEEGETEANNP 502

  Fly   412 QSLGELGLHDGQQLTVTDATSPSAMTLQLKYQSN-----EVEMV 450
            :.|.:.|:.:|.:|...|......:.:.:.:..:     |.|:|
  Rat   503 KKLSDFGIRNGSRLQADDFLQDYTLLINILHSEDLGKDVEFEVV 546

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Uba3	NP_610913.1	ThiF	48..>220	CDD:279270	69/171 (40%)
		Uba3_RUB	50..346	CDD:238765	111/449 (25%)
		E2_bind	357..442	CDD:285976	19/85 (22%)
Uba2	NP_001094049.1	ThiF	9..>175	CDD:279270	68/170 (40%)
		Uba2_SUMO	19..443	CDD:238766	111/448 (25%)
		UAE_UbL	451..537	CDD:291402	20/96 (21%)
		UBA2_C	548..634	CDD:292812

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0476
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D686413at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820