DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Uba3 and Sae1

DIOPT Version :9

Sequence 1:	NP_610913.1	Gene:	Uba3 / 36539	FlyBaseID:	FBgn0263697	Length:	450	Species:	Drosophila melanogaster
Sequence 2:	NP_001012063.1	Gene:	Sae1 / 308384	RGDID:	1306098	Length:	349	Species:	Rattus norvegicus

Alignment Length:	309	Identity:	72/309 - (23%)
Similarity:	119/309 - (38%)	Gaps:	41/309 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    50 QVLIIGAGGLGCELLKDLALMGFGNLHVIDMDTIELSNLNRQFLFRRTDIGASKAECAARFINAR 114
            :|||:|..|||.|:.|:|.|.|...|.::|.:.:...:|..|||.|...:|.::||.:.......
  Rat    41 RVLIVGMKGLGAEIAKNLILAGVKGLTMLDHEQVSPEDLGAQFLIRTGSVGQNRAEASLERAQNL 105

  Fly   115 VPTCRVTPHFKKIQDFDESFYQQFH---LVVCGLDSIV---------ARRWINGMLLSMLRYE-- 165
            .|...|....:.|:...|||:.:|.   |..|..|.|:         :.::..|.:.....|.
  Rat   106 NPMVDVKVDTEDIEKKPESFFTEFDAVCLTCCSKDVIIKVDQICHRNSIKFFTGDVFGYHGYTFA 170

  Fly   166 ---EDGTIDTSSIVPMIDGGTEGFKGNARVILPGFTACIECTLDLFPPQVNYPLCT--------I 219
               |...::..:.|..:..|.|......|..|......:.....||.| |...|..        .
  Rat   171 NLGEHEFVEEKTKVTKVSQGVEDGPDAKRAKLDSSETTMVKKKVLFCP-VKEALAVDWSGEKAQA 234

  Fly   220 ANTPRLPEHCIEYVKIIQWEKQNPFGVPLDGDDPQHIGWIYERAL---ERSNEFNITGVTYRLV- 280
            |.....|::.:..| ::::....       |.||....:..:..|   .|::.|:..||:..|:
  Rat   235 ALKRTAPDYFLLQV-LLKFRTDK-------GRDPTSDSYSEDAELLLQIRNDVFDSLGVSPDLLP 291

  Fly   281 QGVVKHIIPAVASTNAAIAAACALEVFKLATSCYDSMANYLNFNDLDGI 329
            ...|::....:|...|.:....|.|:.| |.|..|...|  ||...||:
  Rat   292 DDFVRYCFSEMAPVCAVVGGILAQEIVK-ALSQRDPPHN--NFFFFDGM 337

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Uba3	NP_610913.1	ThiF	48..>220	CDD:279270	46/194 (24%)
		Uba3_RUB	50..346	CDD:238765	72/309 (23%)
		E2_bind	357..442	CDD:285976
Sae1	NP_001012063.1	Aos1_SUMO	19..344	CDD:238769	72/309 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0476
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900