Protein Alignment Uba3 and Uba6

DIOPT Version :9

• Sequence 1: NP_610913.1
• Gene: Uba3 / 36539
• FlyBaseID: FBgn0263697
• Length: 450
• Species: Drosophila melanogaster
• Sequence 2: NP_001100683.1
• Gene: Uba6 / 305268
• RGDID: 1308324
• Length: 1053
• Species: Rattus norvegicus
• Alignment Length: 641
• Identity: 125/641 - (19%)
• Similarity: 200/641 - (31%)
• Gaps: 284/641 - (44%)

  Fly    20 LRNILEREGPFCKDGFAASSENLEFL-----------------------QTKCQ------VLIIG 55
            |:.:..:..|.|:..:..:::.:|.|                       .|.||      :.::|
  Rat   403 LKAVTGKFSPLCQWLYLEAADTVESLGNLGHEEFLPRGDRYDAFRACIGNTLCQKLQNLNIFLVG 467

  Fly    56 AGGLGCELLKDLALMGFGN------LHVIDMDTIELSNLNRQFLFRRTDIGASKAECAARFINAR 114
            .|.:|||:||:.||:|.|.      :.|.|.|.||.||||||||||...|...|:..||......
  Rat   468 CGAIGCEMLKNFALLGVGTGREKGMVTVTDPDLIEKSNLNRQFLFRPHHIQKPKSYTAAEATLKI 532

  Fly   115 VPTCRVTPHFKKI-----QDFDESFYQQFHLVVCGLDSIVARRWINGMLLSMLRYEEDGTIDTSS 174
            .|..::..|..|:     ..:.:.||.:..:|:..||::.|||:::...|:.||
  Rat   533 NPQLKIDAHLNKVCPATESTYSDEFYNKQDIVITALDNVEARRYVDSRCLANLR----------- 586

  Fly   175 IVPMIDGGTEGFKGNARVILPGFTACIECTLDLFPPQVNYPLCTIANTPRLPEH----------- 228
              |::|.||.|.||:..:|:|..|.......|  ||:...|.||:.:.|...||
  Rat   587 --PLLDSGTMGTKGHTEIIVPQLTESYNSHRD--PPEEEIPFCTLKSFPAAVEHTIQWARDKFES 647

  Fly   229 ----------------------------------CIEYVKIIQ---------------------- 237
                                              |.:.:|::.
  Rat   648 SFSHKPSLFNKFWQAYPSAEDVLQKIQNGQSLEGCFQVIKLLSRRPRMWSQCVELARLKFEKYFN 712

  Fly   238 ----------------------WE--KQNPFGVPLDGDDPQHIGWI------------------- 259
                                  |:  |:.|..:..|.::|.|:.::
  Rat   713 HKALQLLHCFPLDTRLKDGSLFWQSPKRPPSPIKFDLNEPLHLSFLQNAAKLYATVYCIPFSEKD 777

  Fly   260 --------------------------------------------------YERALE--------- 265
                                                              .|:||.
  Rat   778 LSVDSLMDILSEVKIQEFKPSNKVVQTDETARKPDHVPVSSEDERNAVFQLEKALSSNKATKSDL 842

  Fly   266 --------------------------RSNEFNITGVTYRLVQGVVKHIIPAVASTNAAIAAACAL 304
                                      |:..:||........:.:...||||:|::.||::...||
  Rat   843 QMAVLSFEKDDDSNGHIDFITAASNLRAKMYNIEPADRFKTKRIAGKIIPAIATSTAAVSGLVAL 907

  Fly   305 EVFKLATSC-YDSMAN-YLNFNDLDGIYTYTYEAEKSENCLACSNTPQPLPIEDPNTT------T 361
            |:.|:|... :|:..| :||......::|.|.|..|:|.....|.|     |.|..|.      |
  Rat   908 EMIKVAGGYPFDAYKNCFLNLAIPIIVFTETSEVRKTEIRNGISFT-----IWDRWTVHGKEDFT 967

  Fly   362 LEDVIKLLCDSPRFQLKSPALTTVMKDGKRRTLYMSGVKSI------EEATRKNLT 411
            |.|.|..:.:               |.|...|:.:.|||.:      ..|.|..||
  Rat   968 LSDFINAVKE---------------KYGIEPTMVVQGVKMLYVPVMPGHAKRLKLT 1008

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Uba3	NP_610913.1	ThiF	48..>220	CDD:279270	62/188 (33%)
		Uba3_RUB	50..346	CDD:238765	99/509 (19%)
		E2_bind	357..442	CDD:285976	15/67 (22%)
Uba6	NP_001100683.1	Ube1	38..1046	CDD:273603	125/641 (20%)
		Ube1_repeat1	43..428	CDD:238768	4/24 (17%)
		E1_4HB	298..358	CDD:292809
		Ube1_repeat2	462..1005	CDD:238767	114/577 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0476
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810