Protein Alignment Uba3 and Nae1

DIOPT Version :9

• Sequence 1: NP_610913.1
• Gene: Uba3 / 36539
• FlyBaseID: FBgn0263697
• Length: 450
• Species: Drosophila melanogaster
• Sequence 2: NP_659180.1
• Gene: Nae1 / 234664
• MGIID: 2384561
• Length: 534
• Species: Mus musculus
• Alignment Length: 453
• Identity: 96/453 - (21%)
• Similarity: 159/453 - (35%)
• Gaps: 130/453 - (28%)

  Fly     8 PGLILQSKRFNGLRNILEREGPFCKDGFAASSENLEFLQTKCQVLIIGAGGLGCELLKDLALMGF 72
            ||.||:.::::....:....|          .|.||    ...|.:|.|...|.|:||:|.|.|.
Mouse     4 PGKILKEQKYDRQLRLWGDHG----------QEALE----SAHVCLINATATGTEILKNLVLPGI 54

  Fly    73 GNLHVIDMDTIELSNLNRQFLFRRTDIGASKAECAARF---INARVPTCRVTPHFKKIQDFDESF 134
            |:..:||.:.:...:....|..:::.||.::|:.|..|   :|:.|....|....:.:.|.|.||
Mouse    55 GSFTIIDGNLVSGEDAGNNFFLQKSSIGKNRAQAAMEFLQELNSDVSGSFVEESPENLLDNDPSF 119

  Fly   135 YQQFHLVVCGLDSIVARRWINGMLLSMLRYEEDGTIDTSSIVPMIDGGTEGFKGNARVILPGFTA 199
            :.:|.:|       ||.:.:...||.:      ..:..:|.:|::...|.|..|..|:|:....
Mouse   120 FCRFTIV-------VATQLLESTLLRL------ADVLWNSQIPLLICRTYGLVGYMRIIIKEHP- 170

  Fly   200 CIECTLDLFPPQVNYPLCTIANTPRLPEHCIEYVKIIQWEKQNPFGVPLDGDDPQHIGWIYERAL 264
                .::..|......|......|.|.||...| .:...||:          |..|..||..
Mouse   171 ----VIESHPDNALEDLRLDKPFPELREHLQSY-DLDHMEKK----------DHSHTPWIVI--- 217

  Fly   265 ERSNEFNITGVTYRLVQGVVKHIIPAVASTNAAIAAACALEVFKLATSCYDSMANYLNFNDL--D 327
                              :.|::......||..|.               .|.....:|.||  .
Mouse   218 ------------------IAKYLAQWYNETNGRIP---------------KSYKEKEDFRDLIRQ 249

  Fly   328 GIYTYTYEAEKSE--------NCLACSNTPQPLPIEDPNTTTLEDV------IKLLCDSPRFQLK 378
            ||......|.:.|        |.....||.| :|      :::||:      |.:...:|.|.:.
Mouse   250 GILKNENGAPEDEENFEEAIKNVNTALNTTQ-IP------SSIEDIFNDDRCINITKQTPTFWIL 307

  Fly   379 SPALTT-VMKDGK-----RRTL---------YMSGVKSIEEATRKN----------LTQSLGE 416
            :.||.. |.|:|:     |.|:         |:.......|..:|:          |.||:|:
Mouse   308 ARALKEFVAKEGQGNLPVRGTIPDMIADSNKYIKLQNVYREKAKKDAAAVGNHVAKLLQSVGQ 370

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Uba3	NP_610913.1	ThiF	48..>220	CDD:279270	41/174 (24%)
		Uba3_RUB	50..346	CDD:238765	65/308 (21%)
		E2_bind	357..442	CDD:285976	19/91 (21%)
Nae1	NP_659180.1	ThiF	9..>193	CDD:223552	46/215 (21%)
		APPBP1_RUB	11..532	CDD:238770	92/446 (21%)
		Interaction with UBA3. /evidence=ECO:0000250	331..344		1/12 (8%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0476
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900