DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Uba3 and Uba1y

DIOPT Version :9

Sequence 1:	NP_610913.1	Gene:	Uba3 / 36539	FlyBaseID:	FBgn0263697	Length:	450	Species:	Drosophila melanogaster
Sequence 2:	XP_030107423.1	Gene:	Uba1y / 22202	MGIID:	98891	Length:	1087	Species:	Mus musculus

Alignment Length:	248	Identity:	76/248 - (30%)
Similarity:	120/248 - (48%)	Gaps:	41/248 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 FNGLRNILEREGPFCKD-----------GFAASSENLEFLQTKCQVLIIGAGGLGCELLKDLALM 70
            |:.|..:.|....|.:|           ..|....:|:....|.:..::|||.:||||||:.|::
Mouse   425 FDALECLPEHRVAFMEDKCLPHQNRYDGQVAVFGSDLQEKLGKQKYFLVGAGAIGCELLKNFAMI 489

  Fly    71 GF-----GNLHVIDMDTIELSNLNRQFLFRRTDIGASKAECAARFINARVPTCRVTPHFKKI--- 127
            |.     |.:.|.||||||.||||||||||..||...|:|.||..:....|..|:..|..::
Mouse   490 GLGCGEDGEITVTDMDTIEKSNLNRQFLFRPWDITKLKSETAAAAVRDINPHIRIFSHQNRVGPE 554

  Fly   128 --QDFDESFYQQFHLVVCGLDSIVARRWINGMLLSMLRYEEDGTIDTSSIVPMIDGGTEGFKGNA 190
              ..:|:.|:|:...|...||::.||.:::...:...:             |:::.||.|.|||.
Mouse   555 TEHVYDDDFFQKLDGVANALDNVDARLYVDRRCVYYRK-------------PLLESGTLGTKGNV 606

  Fly   191 RVILPGFTACIECTLDLFPPQVNYPLCTIANTPRLPEHCIE-----YVKIIQW 238
            :|::|..|.....:.|  ||:.:.|:||:.|.|...||.::     ..|:.:|
Mouse   607 QVVVPFLTESYSSSQD--PPEKSIPICTLKNFPNAIEHTVQGRLHALKKVARW 657

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Uba3	NP_610913.1	ThiF	48..>220	CDD:279270	63/181 (35%)
		Uba3_RUB	50..346	CDD:238765	68/204 (33%)
		E2_bind	357..442	CDD:285976
Uba1y	XP_030107423.1	Ube1	48..1084	CDD:273603	76/248 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910