DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Uba3 and Uba1

DIOPT Version :9

Sequence 1:	NP_610913.1	Gene:	Uba3 / 36539	FlyBaseID:	FBgn0263697	Length:	450	Species:	Drosophila melanogaster
Sequence 2:	NP_033483.2	Gene:	Uba1 / 22201	MGIID:	98890	Length:	1118	Species:	Mus musculus

Alignment Length:	234	Identity:	72/234 - (30%)
Similarity:	117/234 - (50%)	Gaps:	44/234 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    47 TKCQVLIIGAGGLGCELLKDLALMGF-----GNLHVIDMDTIELSNLNRQFLFRRTDIGASKAEC 106
            :|.:..::|||.:||||||:.|::|.     |.:.|.||||||.||||||||||..|:...|::.
Mouse   527 SKQKYFLVGAGAIGCELLKNFAMIGLGCGEGGEVVVTDMDTIEKSNLNRQFLFRPWDVTKLKSDT 591

  Fly   107 AARFINARVPTCRVTPHFKKI-----QDFDESFYQQFHLVVCGLDSIVARRWINGMLLSMLRYEE 166
            ||..:....|..:||.|..::     :.:|:.|:|....|...||:|.||.:::...:...:
Mouse   592 AAAAVRQMNPYIQVTSHQNRVGPDTERIYDDDFFQNLDGVANALDNIDARMYMDRRCVYYRK--- 653

  Fly   167 DGTIDTSSIVPMIDGGTEGFKGNARVILPGFTACIECTLDLFPPQVNYPLCTIANTPRLPEHCIE 231
                      |:::.||.|.|||.:|::|..|.....:.|  ||:.:.|:||:.|.|...||
Mouse   654 ----------PLLESGTLGTKGNVQVVIPFLTESYSSSQD--PPEKSIPICTLKNFPNAIEH--- 703

  Fly   232 YVKIIQWEKQNPFGVPLDGDDPQHIGWIYERALERSNEF 270
               .:||.:....|             ::::..|..|::
Mouse   704 ---TLQWARDEFEG-------------LFKQPAENVNQY 726

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Uba3	NP_610913.1	ThiF	48..>220	CDD:279270	63/181 (35%)
		Uba3_RUB	50..346	CDD:238765	71/231 (31%)
		E2_bind	357..442	CDD:285976
Uba1	NP_033483.2	ThiF	109..1115	CDD:330201	72/234 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0476
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810