Protein Alignment tum and RGD1

DIOPT Version :9

• Sequence 1: NP_610912.2
• Gene: tum / 36538
• FlyBaseID: FBgn0086356
• Length: 625
• Species: Drosophila melanogaster
• Sequence 2: NP_009819.1
• Gene: RGD1 / 852563
• SGDID: S000000464
• Length: 666
• Species: Saccharomyces cerevisiae
• Alignment Length: 689
• Identity: 145/689 - (21%)
• Similarity: 249/689 - (36%)
• Gaps: 197/689 - (28%)

  Fly     1 MALSALASFDDLRRCMQVLTDGTPEEEFLRFLRMFEQYHEKCAGYAAETARIQNELDKSLTKMGD 65
            :|::||.|    |....:||.    |||::|:|         ..||.|...:| ||.|......:
Yeast    43 VAINALLS----RLKQSLLTC----EEFMKFIR---------KKYAFEEEHVQ-ELSKQYKHFFN 89

  Fly    66 LEG-------KLFHARRIIDMEIKARRQAEHERDAMESKIMAVADLLRHERNLNNETRDKLAFLH 123
            ::|       |:.|  .::..:.|..:..:....|::.....::.||
Yeast    90 IQGSTNSSLKKMIH--EVLGFDGKMAQVKQSYITALQKMYSEISSLL------------------ 134

  Fly   124 TLPSSRKRKSL--NAVREDKSYGD-INST-------GSLLSD---LSITHSEDDFLDVRTSKSWR 175
             |..::.|||:  |:.|.:|...| |:|.       .||..|   |.:|......|.:|.||:.:
Yeast   135 -LTMTKLRKSVKENSKRLEKDVSDAIHSAEKAQSRYNSLCQDWDKLRMTDPTKTKLTLRGSKTTK 198

  Fly   176 EHRPSLPKNQIPSVGNK--RSRLSTGLNGSMSGTTPTTGKSR------------RSSVGIGVEQH 226
            |....|    :..:.|.  ..:.....:.|:..|..|..:.|            .:::.|.::::
Yeast   199 EQEEEL----LRKIDNADLEYKQKVDHSNSLRNTFITKERPRIVQELKDLILEIDTAMTIQLQKY 259

  Fly   227 TVDVGQGAERFCATTKVTI-PQDGQGVIRAESTIESLPVIAG---NER----------------- 270
            |:    ..|.....|.||| |.|         :.:|:...||   |||
Yeast   260 TI----WTENLVLNTGVTISPLD---------STKSMKSFAGSVSNERDLYSFLNKYNQTGKHSL 311

  Fly   271 ------------------------------IGDGLSSTPRRSVLKEATAPPLTPVN--AMAPHVV 303
                                          :....:|.|:|.:.....:|.|:..:  |..|:..
Yeast   312 LINKNLIPVSYKKHPSMNHGQKNKSPPKFAVDPSRNSIPKRMISTHNESPFLSSSSNTAAVPNAN 376

  Fly   304 AESGTP-----LQHRPLMRNHTFS-----------------------QKTFLRGDNCVQCQKRIR 340
            ..|.||     .|..|.|.:...|                       .||...|:|..|..:.:
Yeast   377 LNSATPSLNTNKQLPPTMASSISSTSNAAGAMSPSSSIVTSDTTSSITKTLDPGNNSPQIPEEL- 440

  Fly   341 FGAVGLRCRDCPVRCHIDCRYLLTVSCVPQTGTPTTKTMTGYVTDFAPSIAPMIPALIVHCVNEI 405
               :.....|.|: .||.     |.:.:|.......||....:.........|:||::..|:..|
Yeast   441 ---INSLDSDRPI-SHIQ-----TNNNMPPGVQKNFKTFGVPLESLIEFEQDMVPAIVRQCIYVI 496

  Fly   406 EARGLTEVGLYRLSSSEREYKALKEQFLRGKAT--------PHLGNTDIYVLCCCVKDFLRSLTE 462
            :..||.:.|:||.|::..:...|||:..:..|.        || .::|||::...:|.|..||.:
Yeast   497 DKFGLDQEGIYRKSANVLDVSKLKEEIDKDPANISMILPSKPH-SDSDIYLVGSLLKTFFASLPD 560

  Fly   463 PLIPTSQWKDFANAVQNPDTKTAQDMLVKSVKQLPQANRDTLAFLILHFQRI-AQCPVVLMPIDN 526
            .::|.:...:....:|..|..|.::.:...:..||.|...||..|:.|.:|: |......|.:..
Yeast   561 SVLPKALSSEIKVCLQIEDPTTRKNFMHGLIYNLPDAQYWTLRALVFHLKRVLAHEAQNRMNLRA 625

  Fly   527 ISLIFGPTIVGYSTPDPDQHAIYTEVFTQKQVMKALLEL 565
            :.:|:||||   :..:||.   ..:|..|...|:.|||:
Yeast   626 LCIIWGPTI---APANPDD---ANDVNFQIMAMEVLLEV 658

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tum	NP_610912.2	C1	319..367	CDD:237996	11/70 (16%)
		RhoGAP_MgcRacGAP	381..570	CDD:239847	51/194 (26%)
RGD1	NP_009819.1	F-BAR_Rgd1	39..268	CDD:153336	55/271 (20%)
		RhoGAP_fRGD1	470..663	CDD:239863	51/196 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910