Protein Alignment tum and LRG1

DIOPT Version :9

• Sequence 1: NP_610912.2
• Gene: tum / 36538
• FlyBaseID: FBgn0086356
• Length: 625
• Species: Drosophila melanogaster
• Sequence 2: NP_010041.2
• Gene: LRG1 / 851358
• SGDID: S000002399
• Length: 1017
• Species: Saccharomyces cerevisiae
• Alignment Length: 541
• Identity: 101/541 - (18%)
• Similarity: 189/541 - (34%)
• Gaps: 165/541 - (30%)

  Fly    53 QNELDKSLTKMGDLEGKLFHARRIIDME-IKARRQA----EHERDAMESKIMAVADLLRHERNLN 112
            :|.|..::.|      :..:.|.:.|:: :::||::    .:::.|.:|.|:..|     |.:||
Yeast   520 RNSLQSTMLK------EQTYIRTLNDIKRLRSRRESVRVTHNKQQARKSVILETA-----ETDLN 573

  Fly   113 NETRDKLAFLHTLPSSRKRKSLNAVREDKSYGDINSTGSLLSDLSITHSEDDFLDVRTSKSWREH 177
            :.|:           ....|:|....:|.|.....||...:...:.|.:.||...:..::..||.
Yeast   574 DPTK-----------QGDSKNLVIQTDDPSSSQQVSTRENVFSNTKTLTLDDISRIVAAEQAREL 627

  Fly   178 RPSLPKNQIPSVGNKRSRLSTGLNGSMSGTTPTTGKSRRSSVGIGVEQHTVDVGQGAERFCATTK 242
            ||:       :..:.:....|  :...|...|     ::|.|... |..|:::
Yeast   628 RPN-------AFAHFKKLKET--DDETSNVVP-----KKSGVYYS-ELSTMEL------------ 665

  Fly   243 VTIPQDGQGVIRAESTIESLPVIAGNERIGDGLSSTPRRSVLKEATAPPLTPVNAMAPHVVAESG 307
                    .:|||    .||.::||.:.|              ..|.|..|.:.:|
Yeast   666 --------SMIRA----ISLSLLAGKQLI--------------SKTDPNYTSLVSM--------- 695

  Fly   308 TPLQHRPLMRNHTFSQKTFLRGD--NCVQCQKRIRFGAVGLRCRDCPVRCHIDCRYLLTVSCVPQ 370
                        .||.:..:.|.  |                            |..:.:|..|:
Yeast   696 ------------VFSNEKQVTGSFWN----------------------------RMKIMMSMEPK 720

  Fly   371 TGTPTTKTMTG---------YVTDFAPSIAPM---IPALIVHCVNEIEARGLTEVGLYRLSSSER 423
              .|.|||:.|         :..|....:.|:   ||.:|...::.:....::..|::|.:.:.|
Yeast   721 --KPITKTVFGAPLDVLCEKWGVDSDLGVGPVKIRIPIIIDELISSLRQMDMSVEGIFRKNGNIR 783

  Fly   424 EYKALKEQF-LRGKATPHLGNTDIYVLCCCVKDFLRSLTEPLIPTSQWKDFANA--VQNPDTKTA 485
            ..:.|.... ......|.....:...|...:|.|:|.|.:|::.|..::.:..|  :...|.|..
Yeast   784 RLRELTANIDSNPTEAPDFSKENAIQLSALLKKFIRELPQPILSTDLYELWIKAAKIDLEDEKQR 848

  Fly   486 QDMLVKSVKQLPQANRDTLAFLI--LH----FQRIAQCPVVLMPIDNISLIFGPTIV-------- 536
            ..:|:.|:  ||..||:.|..|:  ||    |..|.......|.|.|:|.:..|.|:
Yeast   849 VILLIYSL--LPTYNRNLLEALLSFLHWTSSFSYIENEMGSKMDIHNLSTVITPNILYLRHKEIS 911

  Fly   537 GYSTPDPDQHAIYTEVFTQKQ 557
            ..:.||..:..: .:.|.|.:
Yeast   912 NDNVPDEPESGL-VDSFAQNK 931

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tum	NP_610912.2	C1	319..367	CDD:237996	5/49 (10%)
		RhoGAP_MgcRacGAP	381..570	CDD:239847	43/206 (21%)
LRG1	NP_010041.2	LIM1_Lrg1p_like	28..90	CDD:188777
		LIM	98..149	CDD:259829
		LIM3_Lrg1p_like	419..475	CDD:188779
		RhoGAP_fLRG1	728..959	CDD:239862	43/207 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910