DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tum and Chn1

DIOPT Version :9

Sequence 1:	NP_610912.2	Gene:	tum / 36538	FlyBaseID:	FBgn0086356	Length:	625	Species:	Drosophila melanogaster
Sequence 2:	XP_038961900.1	Gene:	Chn1 / 84030	RGDID:	620139	Length:	580	Species:	Rattus norvegicus

Alignment Length:	297	Identity:	79/297 - (26%)
Similarity:	133/297 - (44%)	Gaps:	34/297 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   275 LSSTPRRSVLKEATAPPLTPVNAMAPHVVAESGTPLQHRPLMRNHTFSQKTFLRGDN-CVQCQKR 338
            |:|..||:.|||         |...|             ...:.|.|...|| ||.: |..| ..
  Rat   305 LTSLVRRATLKE---------NEQIP-------------KYEKVHNFKVHTF-RGPHWCEYC-AN 345

  Fly   339 IRFG--AVGLRCRDCPVRCHIDCRYLLTVSCVPQTGTPTTKTMTGYVTDFAPSIAPMIPALIVHC 401
            ..:|  |.|::|.||.:..|..|..::...|.|.. ....|..:..:|....:.....|.::..|
  Rat   346 FMWGLIAQGVKCADCGLNVHKQCSKMVPNDCKPDL-KHVKKVYSCDLTTLVKAHITKRPMVVDMC 409

  Fly   402 VNEIEARGLTEVGLYRLSSSEREYKALKEQFLR-GKATPHLGN--TDIYVLCCCVKDFLRSLTEP 463
            :.|||:|||...||||:|......:.:|..|.| |:......|  .||.::...:|.:.|.|..|
  Rat   410 IREIESRGLNSEGLYRVSGFSDLIEDVKMAFDRDGEKADISVNMYEDINIITGALKLYFRDLPIP 474

  Fly   464 LIPTSQWKDFANAVQNPDTKTAQDMLVKSVKQLPQANRDTLAFLILHFQRIA-QCPVVLMPIDNI 527
            ||....:..|..:.:..|.....:.|.::::.||.|:.:||.:|:.|.:|:. .....||..:|:
  Rat   475 LITYDAYPKFIESAKIVDPDEQLETLHEALRSLPPAHCETLRYLMAHLKRVTLHEKENLMSAENL 539

  Fly   528 SLIFGPTIVGYSTPDPDQHAIYTEVFTQKQVMKALLE 564
            .::||||::  .:|:.|..|...::..|:.|::.|::
  Rat   540 GIVFGPTLM--RSPELDPMAALNDIRYQRLVVELLIK 574

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tum	NP_610912.2	C1	319..367	CDD:237996	16/50 (32%)
tum	NP_610912.2	RhoGAP_MgcRacGAP	381..570	CDD:239847	51/188 (27%)
Chn1	XP_038961900.1	SH2_a2chimerin_b2chimerin	163..249	CDD:198215
		C1_alphaCHN	322..378	CDD:410406	17/57 (30%)
		RhoGAP_chimaerin	387..580	CDD:239837	51/190 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910