Protein Alignment tum and ARHGAP28

DIOPT Version :9

• Sequence 1: NP_610912.2
• Gene: tum / 36538
• FlyBaseID: FBgn0086356
• Length: 625
• Species: Drosophila melanogaster
• Sequence 2: NP_001353159.1
• Gene: ARHGAP28 / 79822
• HGNCID: 25509
• Length: 729
• Species: Homo sapiens
• Alignment Length: 539
• Identity: 113/539 - (20%)
• Similarity: 186/539 - (34%)
• Gaps: 154/539 - (28%)

  Fly   144 GDINSTG-SLLSDLSIT---------HSEDDFLDVRTSKSWREHRPSLPKNQIP---SVGNKRSR 195
            ||....| :|||.|:.|         |:....:..:..:|.|:.|.....::.|   :.||..::
Human   128 GDEEEDGKALLSTLTRTQAAAVQKRYHTYTQTMRKKDKQSIRDVRDIFGVSESPPRDTCGNHTNQ 192

  Fly   196 L-STGLNGSMSGTTPTTGKSRRSSVGIGVEQHTVDVGQGAERFCATTKVTIPQDGQG---VIRAE 256
            | .|.....:.....|:| |......:.                :||.....||.:|   |.|::
Human   193 LDGTKEERELPRVIKTSG-SMPDDASLN----------------STTLSDASQDKEGSFAVPRSD 240

  Fly   257 ST--IESLPVIAGNERIGDGLSSTPRRSVLKEATAPPLTPV-NAMAPHVVAESGTPLQHRPLMRN 318
            |.  :|::||:                .|....:..|..|| ||::.....|...|.:...|...
Human   241 SVAILETIPVL----------------PVHSNGSPEPGQPVQNAISDDDFLEKNIPPEAEELSFE 289

  Fly   319 HTFS-----------------------------QKTFL----RGDNCVQCQKRIR---------- 340
            .::|                             |||..    .||...:..|:||
Human   290 VSYSEMVTEALKRNKLKKSEIKKEDYVLTKFNVQKTRFGLTEAGDLSAEDMKKIRHLSLIELTAF 354

  Fly   341 FGAVGLRC----------RDCPVRCHIDCRYLLTVSCVPQTGTPTTKTMTGYVTDFAPSIAPMIP 395
            |.|.|::.          ||..:                 .|.|.|..:.|   |........:|
Human   355 FDAFGIQLKRNKTEKVKGRDNGI-----------------FGVPLTVLLDG---DRKKDPGVKVP 399

  Fly   396 ALIVHCVNEIEARGLTEVGLYRLSSSEREYKALKEQFLRGKATPHLGNTDIY---VLC-----CC 452
            .::.....::|..||...|::|||....:.|..:|: |..|.     |.|.:   .:|     ..
Human   400 LVLQKFFEKVEESGLESEGIFRLSGCTAKVKQYREE-LDAKF-----NADKFKWDKMCHREAAVM 458

  Fly   453 VKDFLRSLTEPLIPTSQWKDFANAVQ-NPDTKTAQDMLVKSVKQLPQANRDTLAFLILHFQR-IA 515
            :|.|.|.|...|.|......|.:.:: .|..|.....|...|..||.||||....|:..|.: ||
Human   459 LKAFFRELPTSLFPVEYIPAFISLMERGPHVKVQFQALHLMVMALPDANRDAAQALMTFFNKVIA 523

  Fly   516 QCPVVLMPIDNISLIFGPTIVGYSTPDPDQHAIYTEVF---TQKQVMKALLELPVSFWE--QYIV 575
            ......|.:.|||.:..|.:. :|.   .:|:.|.|:.   |...:::.:|:.....|:  .:::
Human   524 NESKNRMSLWNISTVMAPNLF-FSR---SKHSDYEELLLANTAAHIIRLMLKYQKILWKVPSFLI 584

  Fly   576 IDPTR-TPATVI--KRVPS 591
            ....| ..||::  |::||
Human   585 TQVRRMNEATMLLKKQLPS 603

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tum	NP_610912.2	C1	319..367	CDD:237996	14/100 (14%)
		RhoGAP_MgcRacGAP	381..570	CDD:239847	49/201 (24%)
ARHGAP28	NP_001353159.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	20..42
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	55..105
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	176..236		13/76 (17%)
		RhoGAP_ARHGAP18	377..588	CDD:239856	53/240 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	612..631

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910