Protein Alignment tum and arhgap18

DIOPT Version :9

• Sequence 1: NP_610912.2
• Gene: tum / 36538
• FlyBaseID: FBgn0086356
• Length: 625
• Species: Drosophila melanogaster
• Sequence 2: NP_001072336.1
• Gene: arhgap18 / 779789
• XenbaseID: XB-GENE-988160
• Length: 662
• Species: Xenopus tropicalis
• Alignment Length: 624
• Identity: 127/624 - (20%)
• Similarity: 203/624 - (32%)
• Gaps: 198/624 - (31%)

  Fly    21 DGTPEEEFLRFLRMFEQYHEKCAGYAAETARIQNELDKSLTKMGDLEGKLFHARRIIDMEIKARR 85
            :|..|||:|:...:...::| ||....|:..:.:.|.|:.:..         .::.||...:..|
 Frog   103 EGELEEEWLKEAGLSNLFNE-CAADPQESIVLLSTLTKTQSAA---------VQKRIDTVTQTLR 157

  Fly    86 QAEHERDAMESKIMAVADLLRHERNLNNETRDKLAFLHTLPSSRKRKSLN------AVREDKSYG 144
            :...:.     :|..|.|:.:...||.::..|...|..|..:..|.:..|      |....::.|
 Frog   158 KKNRQH-----QIPDVRDVFKQPVNLQDKAGDINGFQSTESNDPKNEEANEKAECVAPEASRNVG 217

  Fly   145 DINSTGSLLSDLSITHSED-----DFLDVRTSKSWREHRPSLPKNQIPSVGNKRSRLSTGLNGSM 204
            |.........:|.|:.:|.     ||..||..|   |....||..::
 Frog   218 DDLPVPVTDINLEISFAEQASNLKDFTRVRNEK---EDDSLLPNFRL------------------ 261

  Fly   205 SGTTPTTGKSRRSSVGIGVEQHTVDVGQGAERFCATTKV--TIPQDGQGVIRAESTIESLPVIAG 267
              |...||                           |||:  ..|||    ::..|::..:.:.|.
 Frog   262 --TQDKTG---------------------------TTKIGDLAPQD----MKKVSSLALIELTAL 293

  Fly   268 NERIGDGLSSTPRRSVLKEATAPPLTPVNAMAPHVVAESGTPLQHRPLMRNHTFSQKTFLRGDNC 332
            .:.:|..| ...|.:.:|                 |.|||  |...||        .|.|..|
 Frog   294 YDVLGTEL-KMQRAAKIK-----------------VRESG--LFRVPL--------STLLDQD-- 328

  Fly   333 VQCQKRIRFGAVGLRCRDCPVRCHIDCRYLLTVSCVPQTGTPTTKTMTGYVTDFAPSIAPMIPAL 397
               |||                                  .|.|:                :|.:
 Frog   329 ---QKR----------------------------------APGTR----------------VPLI 340

  Fly   398 IVHCVNEIEARGLTEVGLYRLSSSEREYKALKEQ----FLRGKATPHLGNTDIYVLCCCVKDFLR 458
            ....:..||..||...|:.|:..:....|||.|:    |..|  |.:..|...:.....:|.|:|
 Frog   341 FQSLIGHIEKGGLDTEGILRIPGASARIKALIEELEAKFYEG--TFNWDNVKQHDAASLLKFFIR 403

  Fly   459 SLTEPLIPTSQWKDFANAVQNPDTKTAQDMLVKSVKQLPQANRDTLAFLILHFQRIA----QCPV 519
            .|..||:.....|.|.:....|..|.....|...|..||:.:||||..|:...||:.    |..:
 Frog   404 ELPLPLLTVEYLKAFHSVQYLPTKKHRLQALNLLVILLPEIHRDTLKALLEFLQRVVDHREQNKM 468

  Fly   520 VLMPIDNISLIFGPTIVG---YSTPDPDQHAI---YTEVFTQKQVMKALLELPVSFW--EQYIVI 576
            :|   .|:::|..|.:..   |.....||.|:   ::...| ..||..:::.....|  .::||.
 Frog   469 IL---KNVAMIMAPNLFSVHTYQLKTVDQGALEGAFSAART-ASVMLFMIKYQNLLWTIPKFIVA 529

  Fly   577 DPTRTPATVIKRVPSNKNDLLSLYATPFKGGTIKKRKFY 615
            ...|......|::...|         |.|  .:.||..|
 Frog   530 QVRRQNIVNQKKLSKEK---------PMK--KLLKRMAY 557

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tum	NP_610912.2	C1	319..367	CDD:237996	6/47 (13%)
		RhoGAP_MgcRacGAP	381..570	CDD:239847	48/202 (24%)
arhgap18	NP_001072336.1	RhoGAP_ARHGAP18	316..532	CDD:239856	62/284 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910