Protein Alignment tum and racgap1.2

DIOPT Version :9

• Sequence 1: NP_610912.2
• Gene: tum / 36538
• FlyBaseID: FBgn0086356
• Length: 625
• Species: Drosophila melanogaster
• Sequence 2: XP_031748578.1
• Gene: racgap1.2 / 733574
• XenbaseID: XB-GENE-5952945
• Length: 594
• Species: Xenopus tropicalis
• Alignment Length: 658
• Identity: 188/658 - (28%)
• Similarity: 299/658 - (45%)
• Gaps: 113/658 - (17%)

  Fly     5 ALASFDDLRRCMQVLT-DGTPEEEFLRFLRMFEQYHEKCAGYAAETARIQNELDKSLTKMGDLEG 68
            ||.|:  |.|.::.:. :.:.|:||::..|.||...:|......|....:..|.|...:...|:.
 Frog     8 ALQSY--LDRILKFIEFNVSAEDEFIQVARSFETSRKKLQQTEQELRDKRETLVKCEIERSALQV 70

  Fly    69 KLFHARRIIDMEIKARRQAEHERDAMESKIMAVADLLRHERNLNNETRDK-LAF-----LHTLPS 127
            ||.|||..:|:|:|.|::||.:.:..|.:|..:.|||:.:........|. ||:     :.|.|.
 Frog    71 KLKHARNQVDVEMKKRQRAETKLEKAERQIQLIGDLLKTDGQTAVPLSDSVLAYFGGSRVSTAPQ 135

  Fly   128 SRKRKSLNAVREDKSYGDINSTGSLLSDLSITHSEDDFLDVRTSKSWREHRPSLPKNQIPSVGNK 192
            :..:..|:.|.|        |..|.|||:|..|:||| ||                  :..:|.|
 Frog   136 TAGKSRLSVVDE--------SCTSFLSDISYDHTEDD-LD------------------LDELGGK 173

  Fly   193 RSRLSTGLNGSMSGTTPTTGKSRRSSVGIGVEQHTVDVGQGAERFCATTKVTIPQDGQGVIRAES 257
            .::|........|...|...:.|.|.....|.::.      .|...|.|.:.:...|
 Frog   174 PTKLKARERRRSSLIAPLLKRPRPSEAAAIVAENV------RETVIANTALLVSDTG-------- 224

  Fly   258 TIESLPVIAGNERIGDGLSSTPRRSVLKEATAPPLTPVNAMAPHV--VAESGTPLQHRP---LMR 317
                 |..|        :.:.|||   :...:.||:.:....|.:  :.|....::..|   ..|
 Frog   225 -----PFSA--------VEAAPRR---RSRKSRPLSSLQDQTPALPQINEEEKEMEPEPPPYPTR 273

  Fly   318 NHTFSQKTFLRGDNCVQCQKRIRFGAVGLRCRDCPVRCHIDCRYLLTVSC---VPQTGTPTTKTM 379
            .|.:..:|.:|.:.|:.|.:::|||.:.|:|:||.:..|.:|:......|   :|...| ..|..
 Frog   274 THVYLSRTMIRAELCMVCGQKVRFGKMCLKCKDCRILIHPECKDFCPKVCSSALPSHST-NPKNG 337

  Fly   380 TGYVTDFAPSIAPMIPALIVHCVNEIEARGLTEVGLYRLSSSEREYKALKEQFLRGK-ATPHLGN 443
            .|.:.|:||:..|.:|:.:|.||||||.||.:|.|:||:...:|..|.||::.|:|| ...||..
 Frog   338 PGVLADYAPAAPPRVPSQVVQCVNEIEKRGFSERGIYRIPGCDRLVKELKQKLLQGKIKAQHLAK 402

  Fly   444 TDIYVLCCCVKDFLRSLTEPLIPTSQWKDFANAVQNPDTKTAQDMLVKSVKQLPQANRDTLAFLI 508
            .|::.:|..:|:|.|:|.|||:..|....|.:|....|....:....::|..||..|||||||||
 Frog   403 EDVHTVCGALKEFFRTLQEPLLTYSLHATFLDAADILDECDGRAETCQAVHDLPAPNRDTLAFLI 467

  Fly   509 LHFQRIAQCPVVLMPIDNISLIFGPTIVGYSTPDPDQHAIYTEVFTQKQVMKALLELPVSFWEQY 573
            ||..|:.:.|...|...|:|.|||||:||||.|:|....|..:...|.:||..||.:|.:||:|:
 Frog   468 LHLYRVMRSPECKMDKTNLSRIFGPTLVGYSVPNPSPLMIMQDTPRQAKVMSMLLSIPCAFWDQF 532

  Fly   574 I------------------VIDPTRTP---ATVIKRVP-----SNKNDLLSLYATPFKGGTIKKR 612
            :                  :..|..:|   :.::|..|     |:|:||      |.|.|
 Frog   533 LFTNQENKDGNSAKLDQERLFRPVTSPEINSGLLKASPYLTQSSSKSDL------PKKAG----- 586

  Fly   613 KFYGTPPA 620
            :|:.:|.|
 Frog   587 RFFTSPNA 594

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tum	NP_610912.2	C1	319..367	CDD:237996	14/47 (30%)
		RhoGAP_MgcRacGAP	381..570	CDD:239847	78/189 (41%)
racgap1.2	XP_031748578.1	C1_MgcRacGAP	273..323	CDD:410371	15/49 (31%)
		RhoGAP_MgcRacGAP	336..529	CDD:239847	78/192 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	140	1.000	Domainoid score	I4716
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	301	1.000	Inparanoid score	I2638
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D184774at33208
OrthoFinder	1	1.000	-	-		FOG0004815
OrthoInspector	1	1.000	-	-		otm48467
Panther	1	1.100	-	-	O	PTHR46199
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X3396
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	9.070