Protein Alignment tum and RhoGAP1A

DIOPT Version :9

• Sequence 1: NP_610912.2
• Gene: tum / 36538
• FlyBaseID: FBgn0086356
• Length: 625
• Species: Drosophila melanogaster
• Sequence 2: NP_001284725.1
• Gene: RhoGAP1A / 5740235
• FlyBaseID: FBgn0025836
• Length: 1404
• Species: Drosophila melanogaster
• Alignment Length: 717
• Identity: 151/717 - (21%)
• Similarity: 243/717 - (33%)
• Gaps: 247/717 - (34%)

  Fly    26 EEFLRFLRMFEQYH-------------EKCAGYAAETARIQN------ELDKSLTKMGDLEGK-- 69
            |.|.|...||:.|.             :||:....:..:|.:      :.::||| :.||..|
  Fly   752 EPFRRLAEMFDLYSAFLHNYKNAIETVKKCSANNPQFKKIVSTIVLNLQTEQSLT-LEDLLHKPV 815

  Fly    70 --------------------------LFHARRIIDMEIKARRQAEHERDAMESKIMAVADLLRHE 108
                                      |..|::||.|.:. :....::|..:||           .
  Fly   816 ARVQINALVFNDLLRETPNAHPDHQPLRQAQKIIQMFLN-QFNVVNQRLPIES-----------N 868

  Fly   109 RNLNNETRDKLAFLHTLPSSRKRKSL------NAVREDKSYGDINSTGSL-----LSDLSITHSE 162
            |||....|:.. .:..:...||.:.|      .|..:.|:.|.......|     |.|:||....
  Fly   869 RNLRRMVRNSF-IVELVDGHRKLRHLFLFNDVIACAKYKALGRDRIDYELKWFIPLKDVSIYEEA 932

  Fly   163 DDFLDVRTSKSWREHRP---SLPKNQIPSVGNKRSRLSTGLNGSMSGTTPTTGKSRRSSVGIGVE 224
            |..:::      :|..|   |..|..:.||   |.:|:..:..|.||...:..|.||....:
  Fly   933 DPAVEL------KESSPANISQVKRNLRSV---RDQLAMEVANSGSGAFRSGDKYRRKLADL--- 985

  Fly   225 QHTVDVGQGAERFCATTKVTIPQDGQGVIRAESTIESLPVIAGNERIGDGLSSTPRR-------- 281
                                   :.|.|:...:.:..|...|.|:.|...|||...|
  Fly   986 -----------------------ESQLVLATPNLVLRLGNKANNKTITFFLSSDFERTQWIDSIL 1027

  Fly   282 SVLKEATAPPLTPVN---------AMAPHVVAESGTPLQHRPLMRNHTFSQKTFLRGDNCVQCQK 337
            |:.::...|....:|         ||...:..|.|:     .||||  .:.::.|.||
  Fly  1028 SLKQKCNLPGANTINSLEVTAFIVAMQKGMKTEMGS-----YLMRN--TNDESLLVGD------- 1078

  Fly   338 RIRFGAVGL----RCRDCPVRCHID--------------CR------------------------ 360
             :..|..||    :..|..:...:|              ||
  Fly  1079 -LYMGVHGLEGLEQANDLYICVEVDSYGHYFRKATTKKICRSQTPLWNESFMLELEGSQNVRILL 1142

  Fly   361 --------------YLLTVSCVPQTGTPTTKTMT-----GYVTDFAP------SIAP-------- 392
                          ..|::|.:.:|..|.:..:|     |....|.|      |..|
  Fly  1143 YEAKERPLLKAKHILKLSLSWLTETTQPKSIKLTETLELGCSFRFIPGELFRGSTKPGALFGAKM 1207

  Fly   393 ---------MIPALIVHCVNEIEARGLTEVGLYRLSSSEREYKALKEQFLRG--KATPHLGNTDI 446
                     .||.:|..|:.|:|.||:.|||.||:|.|..:...||:.|...  :|...|...||
  Fly  1208 SQVLKREKRDIPFIIGACIREVERRGMLEVGCYRVSGSASDLAKLKKAFESDAYEAEQLLREVDI 1272

  Fly   447 YVLCCCVKDFLRSLTEPLIPTSQ----WKDFANAVQNPDTKTAQDMLVKSVKQLPQANRDTLAFL 507
            :.:...:|.|||.|.|.|. |.|    :.|..:|..|.:..|..:.|:|..::|||||:.::..:
  Fly  1273 HSVTGILKTFLRELPEALF-TDQLYPRFFDTFSAFSNNNESTRINELLKVFEELPQANKASITSI 1336

  Fly   508 ILHFQRIAQCPV-VLMPIDNISLIFGPTI-------------VGYSTPDPDQHAIYTEVFTQKQV 558
            :.|..|:.:... ..|.:.|::::||||:             :..||.|....|.....|.|.::
  Fly  1337 LDHLIRVHEKETDNKMSLHNLAMVFGPTLLRPGQTQVKQKDPLAASTVDVMAQAGILYCFLQARI 1401

  Fly   559 MK 560
            .|
  Fly  1402 KK 1403

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tum	NP_610912.2	C1	319..367	CDD:237996	11/103 (11%)
		RhoGAP_MgcRacGAP	381..570	CDD:239847	62/223 (28%)
RhoGAP1A	NP_001284725.1	RhoGEF	675..857	CDD:214619	20/106 (19%)
		PH_BCR_arthropod	851..1037	CDD:270174	45/233 (19%)
		C2	1079..1187	CDD:301316	13/107 (12%)
		RhoGAP	1203..1398	CDD:295372	55/195 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910