Protein Alignment tum and arhgap23b

DIOPT Version :9

• Sequence 1: NP_610912.2
• Gene: tum / 36538
• FlyBaseID: FBgn0086356
• Length: 625
• Species: Drosophila melanogaster
• Sequence 2: XP_690730.6
• Gene: arhgap23b / 562244
• ZFINID: ZDB-GENE-081031-78
• Length: 1070
• Species: Danio rerio
• Alignment Length: 571
• Identity: 117/571 - (20%)
• Similarity: 204/571 - (35%)
• Gaps: 177/571 - (30%)

  Fly   116 RDKLA---FLHTLPSSRKR---------------KSLNAVRED-----------KSYGDINSTGS 151
            :|.||   |..:|..||:.               :.||..||:           ||:...:|..|
Zfish   529 QDSLAVIPFKGSLKKSRRSSYMLAITTERSKSCDEGLNTFREEERVLLKLPKRVKSFFTDDSLES 593

  Fly   152 L---------------LSDLSITHSEDDFLDVRTSKSWREHRPSLPKNQIPSVGNKRSRLSTGLN 201
            |               |.::::|       |:| .:.|..::..|        .:||.::.:|:.
Zfish   594 LKVAEDAHSKRHSTSELGNINLT-------DIR-KQGWLHYKQIL--------NDKRKKVGSGMR 642

  Fly   202 ------GSMSGTTPTTGKSRRSSV---------GIGVEQ--HTVDVGQG---------------- 233
                  ..:..:.....|.:|.:|         |||.|:  .|:.: ||
Zfish   643 QWKRVFSVLHSSLLFLYKDKREAVLHATRAGSHGIGQEKDIQTISI-QGCLIDIAYSETKRKHTF 706

  Fly   234 ---AERFCATTKVTIPQDGQ----GVIRAESTIESLPVIAGNERIG------------DGLSSTP 279
               .:.||........:|..    .|||.:|..|       ||.:|            |....:|
Zfish   707 RLMTQDFCEYLLQAEDRDDMLMWIRVIREKSKTE-------NEELGFSRQVLISKKLNDYKKQSP 764

  Fly   280 RRSVLKEATAPPLTPVNAMAPHVVA--ESGTPLQHRPLMRNHTFSQKTFLR---GDNCVQCQKRI 339
            ..:  |..|:|.:..:  |.|..::  |:.:.:...|       .:...:|   |.|..:..|::
Zfish   765 TSN--KPDTSPKMHQM--MPPFFLSKTENASAVSKAP-------GKDESIRAAWGINIKKKGKKM 818

  Fly   340 RFGAVGLRCRDCPVRCHIDCRYLLTVSCVPQTGTPTTKTMTGYVTDFAPSIAPMIPALIVHCVNE 404
            .....|:|..|                |:|....                  ..:|.::..|.:.
Zfish   819 SPKTFGVRLED----------------CLPAASN------------------KFVPQIVETCCSL 849

  Fly   405 IEARGLTEVGLYRLSSSEREYKALKEQFLRGKA--TPHLGNTDIYVLCCCVKDFLRSLTEPLIPT 467
            :|..||...|:||:..:.....:|:||..:|..  |......|:.|:...:|.|.|.|.|||...
Zfish   850 VEEMGLEYTGIYRVPGNNVMVSSLQEQLDKGMVIDTAEERWKDLNVISSLLKSFFRKLPEPLFTD 914

  Fly   468 SQWKDFANAVQNPDTKTAQDMLVKSVKQLPQANRDTLAFLILHFQRIA-QCPVVLMPIDNISLIF 531
            .::.||.:|.:..||......:.|.::.||..|..||.|||.|.:.:| ......|...|::|:|
Zfish   915 DKYNDFIDANRLEDTGDRLKTMRKLIRDLPDHNYHTLKFLIGHLKTVADHSEKNKMEPRNLALVF 979

  Fly   532 GPTIVGYSTPDPDQHAIYTEVFTQKQVMKALLELPVSFWEQYIVIDPTRTP 582
            |||:|  .|.:.:...:.|.:..:.::.:.|:.....|:..  .:|..:||
Zfish   980 GPTLV--RTSEDNMIEMVTHMADRYKITETLILHHTWFFSD--DLDTDKTP 1026

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tum	NP_610912.2	C1	319..367	CDD:237996	7/50 (14%)
		RhoGAP_MgcRacGAP	381..570	CDD:239847	49/191 (26%)
arhgap23b	XP_690730.6	PDZ_signaling	29..136	CDD:238492
		PH	618..735	CDD:278594	21/126 (17%)
		PH_ARHGAP21-like	619..740	CDD:269955	23/130 (18%)
		RhoGAP	822..1016	CDD:295372	54/229 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910