Protein Alignment tum and si:ch1073-416j23.1

DIOPT Version :9

• Sequence 1: NP_610912.2
• Gene: tum / 36538
• FlyBaseID: FBgn0086356
• Length: 625
• Species: Drosophila melanogaster
• Sequence 2: XP_695377.7
• Gene: si:ch1073-416j23.1 / 553480
• ZFINID: ZDB-GENE-100922-35
• Length: 671
• Species: Danio rerio
• Alignment Length: 685
• Identity: 218/685 - (31%)
• Similarity: 321/685 - (46%)
• Gaps: 131/685 - (19%)

  Fly    12 LRRCMQVLT---DGTPEEEFLRFLRMFEQYHEKCAGYAAETARIQNELDKSLTKMGDLEGKLFHA 73
            |..|:|.|.   ....|.||:..:|.||...:|......|..:.:..|.||......||.||.||
Zfish    39 LSLCLQRLAIEEASNSELEFIEVVRNFEAARKKWLHAELELKKQKELLVKSDVARAALEVKLKHA 103

  Fly    74 RRIIDMEIKARRQAEHERDAMESKIMAVADLLRHERN----LNNETRDKL-AFLH---TLPSSRK 130
            |..:|:|||.|.:||.:...:|.::..:.|:|.|:..    ||:|.|..| :|.|   .:|..|
Zfish   104 RNQLDVEIKKRYKAEADYQCLERQMQLICDVLVHDSKSNACLNDEQRSMLTSFSHKGACVPQHR- 167

  Fly   131 RKSLNAVREDKSYGDINSTGSLL--SDLSITHSEDD-------FLDVRTSKSWREHRPSL-PKNQ 185
            .|.|:.:.|          .|.|  ||:|...::||       |:....|::....|.|| |...
Zfish   168 GKRLSVIDE----------SSFLSHSDISYDRTDDDLDLDSTAFVKPLKSRARERRRSSLGPVVS 222

  Fly   186 IPSVGNKRSRLSTGLNGSMSGTTP-------TTGKSRRSSVGIGVEQH-TVDVGQGA-------- 234
            :|.  .||.|:| |.:|.:..:.|       |..|:..|:...|.:.| .:|:.|.|
Zfish   223 LPV--PKRGRIS-GRSGDLLVSRPLEKEIETTVVKASVSTPETGSQIHMVIDITQEAPEHPSRAL 284

  Fly   235 --ERFCATTKVTIPQDGQGVIRAESTIESLPVIAGNERIGDGLSSTPRRSVLKEATAPPLTPVNA 297
              |.|.:..:.|.......||:||:.:|                                ..|:|
Zfish   285 RNEHFSSVAEQTSVWAHSEVIQAETMVE--------------------------------MEVSA 317

  Fly   298 MAPHVVAESGTPLQHRPLMRNHTFSQKTFLRGDNCVQCQKRIRFGAVGLRCRDCPVRCHIDCRYL 362
            :.|.|:.:. ||...:.:  .|.|.|||.:|.:.|:.|.||||||.:.::||||.|..|.:|:.|
Zfish   318 VEPAVLQDL-TPTVEKTV--QHVFQQKTVIRPETCLPCGKRIRFGKLAVKCRDCRVVSHPECKRL 379

  Fly   363 LTVSCVPQ---TGTPTTKTMTGYVTDFAPSIAPMIPALIVHCVNEIEARGLTEVGLYRLSSSERE 424
            ....|.|.   :..|..:|:    ..||||..|.||::||.||:|||.|||.|.|:||:...||:
Zfish   380 CPERCSPNAHGSSHPNEETL----ESFAPSTRPRIPSIIVQCVHEIERRGLEEKGIYRVPGGERQ 440

  Fly   425 YKALKEQFLRGKATPHLGNTD-IYVLCCCVKDFLRSLTEPLIPTSQWKDFANAVQNPDTKTAQDM 488
            .|.|:|::|.||....|...| ::.:|..:|||||.|:||||.....:.|..|.:..|...:.:.
Zfish   441 VKELREKYLYGKGPLMLHKVDEVHAVCGLLKDFLRKLSEPLITFKLHRTFMEASEMADEDKSVET 505

  Fly   489 LVKSVKQLPQANRDTLAFLILHFQRIAQCPVVLMPIDNISLIFGPTIVGYSTPDPDQHAIYTEVF 553
            |:|::::|||.||||||||:||.||:.|.|:..|.::|:|.:|||||:|::..:|....|..:..
Zfish   506 LLKTIRELPQPNRDTLAFLMLHLQRVMQSPLCQMDLNNLSRVFGPTIIGHAMSEPSPMTIMRDTN 570

  Fly   554 TQKQVMKALLELPVSFWEQYIV--IDPTRTPA--TVIKRV-PSNKNDL---------LSLYATPF 604
            ||.:|:..||..|..|||.::.  .||...|.  |.|..| ||...|.         ||.|:...
Zfish   571 TQPRVVARLLSFPSDFWEGFLAEENDPVNPPVIETNIASVCPSTSRDKIFKPLTSPELSKYSKTT 635

  Fly   605 KGGTIK---------------------KRKFYGTP 618
            .||:||                     |:||:.:|
Zfish   636 SGGSIKGRIKHFGGTFNNPSKPRNEPGKKKFFTSP 670

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tum	NP_610912.2	C1	319..367	CDD:237996	22/47 (47%)
		RhoGAP_MgcRacGAP	381..570	CDD:239847	81/189 (43%)
si:ch1073-416j23.1	XP_695377.7	C1	336..384	CDD:237996	22/47 (47%)
		RhoGAP_MgcRacGAP	402..587	CDD:239847	81/184 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	143	1.000	Domainoid score	I4591
eggNOG	1	0.900	-	-		E1_KOG3564
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	299	1.000	Inparanoid score	I2684
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D184774at33208
OrthoFinder	1	1.000	-	-		FOG0004815
OrthoInspector	1	1.000	-	-		otm26367
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR46199
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X3396
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	12	11.930