DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tum and arhgap17a

DIOPT Version :9

Sequence 1:	NP_610912.2	Gene:	tum / 36538	FlyBaseID:	FBgn0086356	Length:	625	Species:	Drosophila melanogaster
Sequence 2:	NP_001017592.2	Gene:	arhgap17a / 550254	ZFINID:	ZDB-GENE-050417-56	Length:	847	Species:	Danio rerio

Alignment Length:	248	Identity:	55/248 - (22%)
Similarity:	96/248 - (38%)	Gaps:	73/248 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   401 CVNEIEARGLTEVGLYRLSSSEREYKALK----------EQFLRGKATPHLGNTDIYVLCCCVKD 455
            ||..:...|:.|.||:|:::...:.|.||          |:|.          :|.:.:...:|.
Zfish   275 CVMMLLETGMKEEGLFRIAAGASKLKKLKAALDCSTSQLEEFY----------SDPHAVAGALKS 329

  Fly   456 FLRSLTEPLIPTSQWKDFANAVQNPDTKTAQDMLVKSVKQLPQANRDTLAFLILHFQRIAQ-CPV 519
            :||.|.|||:....:.::..|...||.......|..:..|||:.|:....:|:....::|| ..|
Zfish   330 YLRELPEPLMTYQLYDEWIQASNVPDPDKRLQALWVTCDQLPKNNKANFRYLVKFLAKLAQESDV 394

  Fly   520 VLMPIDNISLIFGPTIVGYSTP------------------DP-DQHAIYTEVFTQKQV---MKAL 562
            ..|...||:::.||.::...|.                  || .|||   :.|..:.|   :..:
Zfish   395 NKMTPSNIAIVLGPNLLWAKTEGSLAEMAAATSVHVVTIIDPIIQHA---DWFFPEDVDFNVSGM 456

  Fly   563 LELPVSFWEQYIVIDPTRTPATVIKRVPSNKNDLLSLYATP--FKGGTIKKRK 613
            ..:|..                    :|:|.|.|     ||  :..|||::::
Zfish   457 FSMPAP--------------------LPNNVNHL-----TPPDYDSGTIERKR 484

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tum	NP_610912.2	C1	319..367	CDD:237996
tum	NP_610912.2	RhoGAP_MgcRacGAP	381..570	CDD:239847	46/201 (23%)
arhgap17a	NP_001017592.2	BAR	13..260	CDD:386243
arhgap17a	NP_001017592.2	RhoGAP_nadrin	249..449	CDD:239851	44/186 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910