DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tum and arhgap17

DIOPT Version :9

Sequence 1:	NP_610912.2	Gene:	tum / 36538	FlyBaseID:	FBgn0086356	Length:	625	Species:	Drosophila melanogaster
Sequence 2:	XP_002932512.1	Gene:	arhgap17 / 549590	XenbaseID:	XB-GENE-981776	Length:	856	Species:	Xenopus tropicalis

Alignment Length:	307	Identity:	60/307 - (19%)
Similarity:	116/307 - (37%)	Gaps:	88/307 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   369 PQTGTPTTKTMTGYVTDFAPSIAPMIPALIVHCVNEIEARGLTEVGLYRLSSSEREYKALK---- 429
            |..|||..:.:.....:.|      :|  |..||..:...|:.|.||:|:::...:.|.||
Frog   248 PAFGTPLEEHLKRSGREIA------LP--IEACVMMLLETGMKEEGLFRIAAGASKLKKLKAALD 304

  Fly   430 ------EQFLRGKATPHLGNTDIYVLCCCVKDFLRSLTEPLIPTSQWKDFANAVQNPDTKTAQDM 488
                  |:|.          :|.:.:...:|.:||.|.|||:..:.::::.:|...||..|....
Frog   305 CSTSQLEEFY----------SDPHAVAGALKSYLRELPEPLMTFNLYEEWNHAGNIPDQNTKLQA 359

  Fly   489 LVKSVKQLPQANRDTLAFLILHFQRIA-QCPVVLMPIDNISLIFGPTIVGYSTPDPDQH------ 546
            |....::||:.|.:...:|:....::: ...:..|...||:::.||.::.      .:|
Frog   360 LWVVCQKLPKPNLENFRYLVKFLAKLSHHSDINKMTPSNIAIVLGPNLLW------ARHEGTLAE 418

  Fly   547 -AIYTEVFTQKQVMKALL---------ELPVSFWEQYIVIDPTRTPATVIKRVPSNKNDL----- 596
             |..|.|... .:::.::         ||..:....::.:.||    |....||...||:
Frog   419 IAAATSVHVM-TIIEPIIQHADWFFPDELDFNVSGAFVPVAPT----THSNNVPYTGNDMSYEFG 478

  Fly   597 -------------------------LSLYATPFKGGTIKKRKFYGTP 618
                                     :..|....:|||:.::  :|.|
Frog   479 PLEKKRPFSMVMDGELKRDSSGLKVMDYYLNTRRGGTLNRK--HGAP 523

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tum	NP_610912.2	C1	319..367	CDD:237996
tum	NP_610912.2	RhoGAP_MgcRacGAP	381..570	CDD:239847	43/215 (20%)
arhgap17	XP_002932512.1	BAR	13..257	CDD:386243	4/8 (50%)
		RhoGAP_nadrin	246..445	CDD:239851	45/221 (20%)
		DUF5585	515..>849	CDD:375359	3/11 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910