Protein Alignment tum and racgap1

DIOPT Version :9

• Sequence 1: NP_610912.2
• Gene: tum / 36538
• FlyBaseID: FBgn0086356
• Length: 625
• Species: Drosophila melanogaster
• Sequence 2: NP_001001236.1
• Gene: racgap1 / 407917
• XenbaseID: XB-GENE-943983
• Length: 629
• Species: Xenopus tropicalis
• Alignment Length: 646
• Identity: 214/646 - (33%)
• Similarity: 323/646 - (50%)
• Gaps: 99/646 - (15%)

  Fly     9 FDDLRRCMQVLTDGTPEEEFLRFLRMFEQYHEKCAGYAAETARIQNELDKSLTKMGDLEGKLFHA 73
            |:.|.|.:..|.:|. |.:|::..:.||.:..|......|..:.:..|.|:.|:...||.||.||
 Frog    12 FEQLMRQVDGLNEGI-EPQFIQLAKNFEDFRRKWQKSEQELIKNKEMLMKTETERSALEVKLKHA 75

  Fly    74 RRIIDMEIKARRQAEHERDAMESKIMAVADLLRHERN----LNNETRDKLAFLHTLPSSRKRKSL 134
            |..:|:|||.|::||.|.:.:|.:|..:.:||..:.:    |:.:.|..||||    ::|.:.|.
 Frog    76 RNQVDVEIKRRQRAEVECEKLERQIQLIRELLMCDPSGSIQLSEQQRSALAFL----NNRTQMSA 136

  Fly   135 --NAVREDKSYGDINSTGSLLSDLSITHSEDDFLDVRTS-------KSWREHRPSLPKNQIPSVG 190
              |..|.   ...|:.:.|:|||:|...:||. ||..:|       |...:.|.|....:.|.|.
 Frog   137 DGNGTRR---LSTIDESASILSDISFDKTEDS-LDWDSSLVRNVRLKKREKRRSSRQHTEGPPVP 197

  Fly   191 NKRSRLSTGLNGSMSGTTPTTGKSRRSSVGIGVEQHTVDVGQGAERFCATTKVTIPQDGQGVIRA 255
            :||:|                      |:.|.::       |..|...|.|.:|:|.:| |.|..
 Frog   198 SKRNR----------------------SIEIAMD-------QANESIIAKTTLTVPNNG-GPIDV 232

  Fly   256 ESTIESLPVIAGNERIGDGLSSTPRRSVLKEATAPPLTPVNAMAPHVVAESG------TPLQHRP 314
            .|:||::|......|              :..|..|....:::....:...|      ||  ...
 Frog   233 VSSIETVPYYNTRSR--------------RTGTLQPWNSDSSLVSRHLDHKGEADTCRTP--QNG 281

  Fly   315 LMRNHTFSQKTFLRGDNCVQCQKRIRFGAVGLRCRDCPVRCHIDCRYLLTVSCVPQTGTPTTKTM 379
            .||.|.|..||.::.::||.|.|||:||.:.|:||||.|..|.:||....:.|:|..|....:..
 Frog   282 GMRLHEFVSKTVIKPESCVPCGKRIKFGKISLKCRDCRVVAHPECRERCPLPCIPTVGGTPVRIG 346

  Fly   380 TGYVTDFAPSIAPMIPALIVHCVNEIEARGLTEVGLYRLSSSEREYKALKEQFLRGKATPHLGNT 444
            .|.:.||||..:||||.:|||||:||:.|||.|.||||:|..:|..|.|||:|||||:.|.|...
 Frog   347 EGTLADFAPLTSPMIPPIIVHCVSEIQQRGLHETGLYRISGCDRTVKELKEKFLRGKSVPLLSKV 411

  Fly   445 -DIYVLCCCVKDFLRSLTEPLIPTSQWKDFANAVQNPDTKTAQDMLVKSVKQLPQANRDTLAFLI 508
             ||:.:|..:|||||:|.|||:.....:.|..|.:..|.|::...:.::|.:||..||||||:|:
 Frog   412 DDIHAVCGFLKDFLRNLKEPLLTFRLNRVFMEAAEITDEKSSIAAIYQAVDELPAPNRDTLAYLM 476

  Fly   509 LHFQRIAQCPVVLMPIDNISLIFGPTIVGYSTPDPDQHAIYTEVFTQKQVMKALLELPVSFWEQY 573
            :|.||:||.|...|.:.|:|.:||||:||::.||||...|..:...|..|::.|:.||..||.|:
 Frog   477 IHLQRVAQSPDCKMDVSNLSKVFGPTLVGHAVPDPDPMTILQDTRRQPMVVERLMLLPAEFWNQF 541

  Fly   574 IV---IDPT---------RTPATVIKRVPSNKNDLLSLYATPFKGGTIKKRKFYGTPPASA 622
            ::   |||.         .||     |.|..:..:|....||       :::|..||.:|:
 Frog   542 MMVENIDPNHIIENANVFNTP-----RTPDARVSMLGPLTTP-------EQQFNKTPSSSS 590

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tum	NP_610912.2	C1	319..367	CDD:237996	21/47 (45%)
		RhoGAP_MgcRacGAP	381..570	CDD:239847	88/189 (47%)
racgap1	NP_001001236.1	SbcC	<8..107	CDD:223496	31/95 (33%)
		C1	286..334	CDD:237996	21/47 (45%)
		RhoGAP_MgcRacGAP	345..538	CDD:239847	88/192 (46%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	140	1.000	Domainoid score	I4716
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H8077
Inparanoid	1	1.050	301	1.000	Inparanoid score	I2638
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D184774at33208
OrthoFinder	1	1.000	-	-		FOG0004815
OrthoInspector	1	1.000	-	-		otm48467
Panther	1	1.100	-	-	LDO	PTHR46199
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4412
SonicParanoid	1	1.000	-	-		X3396
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	10	10.190