Protein Alignment tum and RhoGAP18B

DIOPT Version :9

• Sequence 1: NP_610912.2
• Gene: tum / 36538
• FlyBaseID: FBgn0086356
• Length: 625
• Species: Drosophila melanogaster
• Sequence 2: NP_573352.2
• Gene: RhoGAP18B / 32898
• FlyBaseID: FBgn0261461
• Length: 1317
• Species: Drosophila melanogaster
• Alignment Length: 636
• Identity: 125/636 - (19%)
• Similarity: 213/636 - (33%)
• Gaps: 199/636 - (31%)

  Fly    54 NELDKSLTKMGDLEGKLFHARRIIDMEIKARRQAEHERDAMESKIMAV-ADLLRHERNLNNET-R 116
            :::|.....:||.:..|               .::.:.|.|..:..|| |..:||:.:.:..| |
  Fly   741 DDVDDEEEDLGDYDESL---------------PSDADPDVMALQAAAVFAAGVRHKLSTSTLTKR 790

  Fly   117 DKLAFLHTLPS------------------SRKRK-------SLNA--VREDKSYGDINSTGS--- 151
            .|:.....|||                  ||:.|       ||.:  .....:.|.|:||||
  Fly   791 SKMMMPTPLPSPTASMDHGAWETDMEFMYSRESKEEADETLSLGSTVTNSTATLGSISSTGSSVT 855

  Fly   152 ----------------------LLSDLSITHSEDD-------FLDVRTSK-----SWREHRPSLP 182
                                  :|.::.|.:|:.|       |.|...|.     ..|..||:.|
  Fly   856 GQPKDTPKDLPADQQPSVVVHPILRNICIFYSQKDPKKYSAIFYDYHLSLVHQRFMTRIRRPAPP 920

  Fly   183 ---------------------------------KNQIPSVGN------KRSRLSTGLNGSMSGTT 208
                                             .|..|::..      :|:.|:.|......|..
  Fly   921 PPAQLATSNTTSLAPRSDDSGCSCEAEDSYNHQHNPTPAIPKPLKEEWERAVLAAGAVAGKRGVA 985

  Fly   209 PTTGKSRR----------SSVGIGVEQHTVDVGQGAERFCATTKVTIPQDGQGVIRAESTIESLP 263
            |.||:..|          .|| :...:...||.      |...:..:......::||:...|.
  Fly   986 PRTGRKLRVRSNARLLLTDSV-LAWRETLQDVN------CCEDEEDMIVPVTDILRAQQIQED-- 1041

  Fly   264 VIAGNERIGDGLSSTPRRSVLKEATAPPLTPVNAMAPHVVAESGTPLQHRPLMRNHTFSQKTFLR 328
                ||     :..|.:.::|:...:   ..:..:......:....:::|..|:....|....:.
  Fly  1042 ----NE-----VQQTQQSTILQRYKS---VSIGNLLDLPGEDDKKSIKNRMRMKFAVNSNVFRIN 1094

  Fly   329 GDNCVQCQKRIRFGAVGLRCRDCPVRCHIDCRYLLTVSCVPQTGTPTTK---TMTGYVTDFAPSI 390
            .....:.:.|.|.|.|.....|       :.:|       |....|.:.   .||.:
  Fly  1095 RSPKSEKKSRSRRGQVNSLYLD-------EQKY-------PLFAAPLSALELNMTDH-------- 1137

  Fly   391 APMIPALIVH-CVNEIEARGLTEVGLYRLSSSEREYKALKEQFLRGKAT----PH-LGNTDIYVL 449
             |.:|..:|. |....:...:.:.||||.|.:    |.|.:: ||.|.|    |. |...||:.|
  Fly  1138 -PNVPRFVVDVCAYIEQPECIEQDGLYRASGN----KVLVDE-LRKKLTHVYDPRWLKTDDIHTL 1196

  Fly   450 CCCVKDFLRSLTEPLIPTSQWKDFANAVQNPDTKTAQDMLVKSVKQLPQANRDTLAFLILHFQRI 514
            ....|.|.|.||.|||....::....:: |.|  .|.:.:..:...:|:.||.||.|||.|..|:
  Fly  1197 TSLHKQFFRELTSPLITQEAYERLGRSL-NDD--AAIERMSLAFDDMPEPNRSTLRFLIRHLTRV 1258

  Fly   515 AQCPVV-LMPIDNISLIFGPTIVGYSTPDPDQHAIYTEVFTQKQVMKALLE 564
            |..... .||..|:::::||.::       ..:.|..::.....:.|.|:|
  Fly  1259 AAASASNRMPSTNLAIVWGPCLL-------SANQIQLDIGRMNMLAKVLIE 1302

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tum	NP_610912.2	C1	319..367	CDD:237996	7/47 (15%)
		RhoGAP_MgcRacGAP	381..570	CDD:239847	51/191 (27%)
RhoGAP18B	NP_573352.2	RhoGAP	1141..1289	CDD:279014	47/162 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3564
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810