Protein Alignment tum and racgap1

DIOPT Version :9

• Sequence 1: NP_610912.2
• Gene: tum / 36538
• FlyBaseID: FBgn0086356
• Length: 625
• Species: Drosophila melanogaster
• Sequence 2: NP_955925.1
• Gene: racgap1 / 323197
• ZFINID: ZDB-GENE-030131-1917
• Length: 654
• Species: Danio rerio
• Alignment Length: 687
• Identity: 223/687 - (32%)
• Similarity: 331/687 - (48%)
• Gaps: 124/687 - (18%)

  Fly     9 FDDLRRCMQVLTDGTPEEEFLRFLRMFEQYHEKCAGYAAETARIQNELDKSLTKMGDLEGKLFHA 73
            |:.||....||.:.. |.:|::....||....:......|....:..|.|:.|:.|.||.||.||
Zfish    12 FESLRAQADVLNESI-EPQFIQLAINFEDNRRRWLRLEQELNACKEVLTKAETERGALEVKLKHA 75

  Fly    74 RRIIDMEIKARRQAEHERDAMESKIMAVADLLRHERN-----LNNETRDKLAFLHTLPSSRKRKS 133
            |..:|:||:.|::||.:...::.:|..:.:||..|.:     ||.|.|..||||:.  .|:...:
Zfish    76 RNQVDVEIRRRQKAESDCAKLDRQIQLIRELLVSEGSSSSIQLNEEQRSALAFLNA--RSQNPAN 138

  Fly   134 LNAVREDKSYGDINSTGSLLSDLSITHSEDDFLD-----VRT--SKSWREHRPSLPKNQIPSVGN 191
            ||..|.   ...|:.:.|:|||:|...: ||.||     :||  .|..::.|.|....:.|....
Zfish   139 LNTSRR---LATIDESASILSDISYDKT-DDSLDWDSSAIRTVRLKKRQKRRSSRNHTEGPPAAA 199

  Fly   192 KRSRLSTGLNGSMSGTTPTTGKSRRSSVGIGVEQHTVDVGQGAERFCATTKVTIPQDGQGVIRAE 256
            ||||              :||::..               :|.|...|.|.||:|.|| |.|.|.
Zfish   200 KRSR--------------STGRTSE---------------KGNESLVAKTTVTVPADG-GPIEAV 234

  Fly   257 STIESLP---------VIAGNER-IGDGLS------------STPRRSVLKEATAPPLTPVNAMA 299
            :|:|::|         |...:|: |....|            |.....|.|:.:.|     ||
Zfish   235 TTVEAVPYWTRSRRKTVFCSSEQCISLNYSSAAVEWDTVDTDSVQSMDVFKQPSLP-----NA-- 292

  Fly   300 PHVVAESGTPLQHRPLMRNHTFSQKTFLRGDNCVQCQKRIRFGAVGLRCRDCPVRCHIDCRYLLT 364
             ...||..|| |....:|.|.|..||.::.::||.|.|||:||.:.|:||||.|..|.:||....
Zfish   293 -ENRAEPSTP-QGNGGVRLHEFISKTVIKPESCVPCGKRIKFGKISLKCRDCRVVAHPECRERCP 355

  Fly   365 VSCVP-QTGTPTTKTMTGYVTDFAPSIAPMIPALIVHCVNEIEARGLTEVGLYRLSSSEREYKAL 428
            :.|:| .|||| .|...|.:.::..:.:||||:|:|||:||||.|||.|.||||:|.|:|..|.|
Zfish   356 LPCIPSMTGTP-VKIGEGTLANYVSNTSPMIPSLVVHCINEIEQRGLHETGLYRVSGSDRVVKDL 419

  Fly   429 KEQFLRGKATPHLGNT-DIYVLCCCVKDFLRSLTEPLIPTSQWKDFANAVQNPDTKTAQDMLVKS 492
            ||:|||||..|.|... ||:.:...:|||||:|.|||:.....:.|.:|.:..|...:..::.::
Zfish   420 KEKFLRGKTVPLLSKVEDIHAITGLLKDFLRNLKEPLLTFRLNRAFMDAAELSDDDNSIALMYQN 484

  Fly   493 VKQLPQANRDTLAFLILHFQRIAQCPVVLMPIDNISLIFGPTIVGYSTPDPDQHAIYTEVFTQKQ 557
            :..|||.:||||||||:|.||:||.|...|.|.|::.:|||||||::..:|:...|..:...|.:
Zfish   485 ISDLPQPHRDTLAFLIIHLQRVAQSPATKMDITNLARVFGPTIVGHAVSNPEPMTILQDTKRQPR 549

  Fly   558 VMKALLELPVSFWEQYIVID----------------------------PTRTPATVIKRVPSN-- 592
            |::.||.|||.:|.|:::.|                            |..||...:.:.||:
Zfish   550 VVERLLSLPVEYWSQFMISDHDHARNDHMIIENANVHTTPDQKMSMFGPITTPDQQMSKTPSSSS 614

  Fly   593 -----KNDLLSLYATPFK------GGTIKKRKFYGTP 618
                 ||..|:.....|.      ....::..|:.:|
Zfish   615 LSQRMKNATLNAITPKFSSRSRATAAVPRQGNFFASP 651

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tum	NP_610912.2	C1	319..367	CDD:237996	21/47 (45%)
		RhoGAP_MgcRacGAP	381..570	CDD:239847	85/189 (45%)
racgap1	NP_955925.1	C1	310..358	CDD:237996	21/47 (45%)
		RhoGAP_MgcRacGAP	369..562	CDD:239847	85/192 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	143	1.000	Domainoid score	I4591
eggNOG	1	0.900	-	-		E1_KOG3564
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H8077
Inparanoid	1	1.050	299	1.000	Inparanoid score	I2684
OMA	1	1.010	-	-		QHG49807
OrthoDB	1	1.010	-	-		D184774at33208
OrthoFinder	1	1.000	-	-		FOG0004815
OrthoInspector	1	1.000	-	-		otm26367
orthoMCL	1	0.900	-	-		OOG6_106233
Panther	1	1.100	-	-	LDO	PTHR46199
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4412
SonicParanoid	1	1.000	-	-		X3396
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	15	14.870