Protein Alignment tum and Arhgap26

DIOPT Version :9

• Sequence 1: NP_610912.2
• Gene: tum / 36538
• FlyBaseID: FBgn0086356
• Length: 625
• Species: Drosophila melanogaster
• Sequence 2: XP_006254722.1
• Gene: Arhgap26 / 307459
• RGDID: 1310923
• Length: 814
• Species: Rattus norvegicus
• Alignment Length: 604
• Identity: 115/604 - (19%)
• Similarity: 213/604 - (35%)
• Gaps: 186/604 - (30%)

  Fly    89 HERDAMESKIMAVADLLRHERNLNNETRDKLAFLHTLP--SSRKRKSLNAVREDK--SYGDINST 149
            |.|:.::|.   .|:|.:..:.:....:|..:.:..|.  ||.|||..:::.|.|  ..||..:.
  Rat    17 HFRETLKSH---EAELDKTNKFIKELIKDGKSLISALKNLSSAKRKFADSLNEFKFQCIGDAETD 78

  Fly   150 GSLLSDLSITHSEDDFLDVRTSKSWREHRPSLPKNQIPSVGNKRSRLSTGLNGSMSGTTPTTGKS 214
                .::.|..|..:|..|                 :.::.::|||:..  |.|....||.. |.
  Rat    79 ----DEMCIARSLQEFATV-----------------LRNLEDERSRMIE--NASEVLITPLE-KF 119

  Fly   215 RRSSVGIGVEQHTVDVGQGAERFCATTK----VTIPQDGQGVIRAESTIESL------------- 262
            |:..:|...|... ...:..|::|.|.:    ::..:....:..|:|.::.:
  Rat   120 RKEQIGAAREAKK-KYDKETEKYCGTLEKHLNLSSKKKESQLQEADSQVDLVRQHFYEVSLEYVF 183

  Fly   263 ---------------PVIA-----------GNERIGD----------GLSSTPRR---------S 282
                           |::|           |.|...|          .:.:|..|         |
  Rat   184 KVQEVQERKMFEFVEPLLAFLQGLFTFYHHGYELAKDFGDFKTQLTISIQNTRNRFEGTRSEVES 248

  Fly   283 VLKEATAPPLTPVNAMAPHVVAESGTPLQHRPL----MRNHTFSQKTFLRGDNCVQ--C-----Q 336
            ::|:.                  ...||:|:.:    |..:.:.|:....|.:.|:  |     .
  Rat   249 LMKKM------------------KENPLEHKTISPYTMEGYLYVQEKRHFGTSWVKHYCTYQRDS 295

  Fly   337 KRI-------RFGAVG-----LRCRDCPVR--CHIDCRYLLTVSCVPQTGTPTTKTM-------- 379
            |:|       :.|..|     :..:.|..|  ..|:.|:...|..|.:.|..|.:.:
  Rat   296 KQITMVPFDQKSGGKGGEDESVTLKSCTRRKTDSIEKRFCFDVEAVDRPGVITMQALSEEDRRLW 360

  Fly   380 ---------------------TGYVTDFAPSIAPMIPALIVHCVNEIEARGLTEVGLYRLSSSER 423
                                 |..:.....||       |..|::.:|.||:.|.||||:.....
  Rat   361 MEAMDGREPVYNSNKDSQSEGTAQLDSIGFSI-------IRKCIHAVETRGINEQGLYRIVGVNS 418

  Fly   424 EYKALKEQFLRGKA-----TPHLGNTDIYVLCCCVKDFLRSLTEPLIPTSQWKDFANA--VQNPD 481
            ..:.|....:..||     |......:|..:...:|.:||.|..||:.....:.|..|  ::|.:
  Rat   419 RVQKLLSVLMDPKAASETETDICAEWEIKTVTSALKTYLRMLPGPLMMYQFQRSFIKAAKLENQE 483

  Fly   482 TKTAQDMLVKSVKQLPQANRDTLAFLILHFQRIA-QCPVVLMPIDNISLIFGPTIVGYSTPDPDQ 545
            |:.::  :...|.:||:.||..|..|:.|...:| .....||.:.|:.::||||::   .|..:.
  Rat   484 TRVSE--IHSLVHRLPEKNRQMLQLLMNHLANVANNHKQNLMTVANLGVVFGPTLL---RPQEET 543

  Fly   546 HAIYTEVFTQKQVMKALLE 564
            .|...::..|..|::.|:|
  Rat   544 VAAIMDIKFQNIVIEILIE 562

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tum	NP_610912.2	C1	319..367	CDD:237996	13/68 (19%)
		RhoGAP_MgcRacGAP	381..570	CDD:239847	49/192 (26%)
Arhgap26	XP_006254722.1	BAR_GRAF	19..225	CDD:153320	40/233 (17%)
		BAR-PH_GRAF_family	267..371	CDD:269953	17/103 (17%)
		PH	267..364	CDD:278594	17/96 (18%)
		RhoGAP_Graf	364..563	CDD:239839	50/211 (24%)
		SH3_GRAF	759..814	CDD:212997

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910