Protein Alignment tum and Gmip

DIOPT Version :9

• Sequence 1: NP_610912.2
• Gene: tum / 36538
• FlyBaseID: FBgn0086356
• Length: 625
• Species: Drosophila melanogaster
• Sequence 2: NP_001100778.1
• Gene: Gmip / 306357
• RGDID: 1565577
• Length: 969
• Species: Rattus norvegicus
• Alignment Length: 657
• Identity: 148/657 - (22%)
• Similarity: 240/657 - (36%)
• Gaps: 192/657 - (29%)

  Fly    10 DDLRRCMQVLTDGTPEEEFLRFLRMFEQYHEKCAGYAAETARIQNELDKSLTKMGDLEGKLFHA- 73
            :|||    ..|.|:||:..|          :...|...:..|.:...:::..|..:.|. |:.|
  Rat   228 EDLR----ARTQGSPEDPPL----------QASPGSNKQQERRRRSREEAQAKAHEAEA-LYQAC 277

  Fly    74 -----RRIIDMEIKARRQAEHERDAMESKIMAVADLLRHERNLNNETRDKLAFLHTLPSSRKRKS 133
                 .|..|:|...||...|.|     |::...|.:.....|.      |..|....:.|..:|
  Rat   278 VREANTRQQDLETTKRRIVSHVR-----KLVLQGDEVLRRVTLG------LFELRGAQAERGPRS 331

  Fly   134 LNAVRE-------DKSYGDI-----------NSTGSLLSDLS-ITHS--EDDFLDVRTSKSWR-- 175
            .:|:.|       .:.|.:.           .|......:.: :.||  :|      |.|.:.
  Rat   332 FSALAECCVPFEPGQRYQEFVRSLQPGAPPPPSPAFCFQEFAPVVHSFPQD------TKKKFSGP 390

  Fly   176 -----EHRPSLPKN-QIPSVGNKRSRLSTGLNGSMSGTTPTTGKSRRSSVGIGVEQHTVD----- 229
                 |..||.|.. ::.|:|      |.|:.|           |...|||.|.|..::|
  Rat   391 LPTRLEEGPSEPGPWEVASLG------SQGIPG-----------SDVDSVGGGSESRSLDSPTSS 438

  Fly   230 VGQGAERFCATTKVTIPQDGQGVIRAESTIESLPVIAGNER----------IGDGLSSTPRRSVL 284
            .|.||.|               :::|.||        |.|.          :|||:.:
  Rat   439 PGAGARR---------------LVKASST--------GTESSDDFEERDPDLGDGMEN------- 473

  Fly   285 KEATAPPLTPVNAMAPHVVAESGTPLQHRPLMRNHTFSQKTFLRGD-NCVQCQKRIRFGAVGLRC 348
                                .:|:|.:...|.......:...|||. .|.:|:   .|...|..|
  Rat   474 --------------------GTGSPFRKWTLSTAAQTHRLRRLRGPAKCRECE---AFMVSGTEC 515

  Fly   349 RDCPVRCHIDCRYLLTVSCVPQTGTPTTKTMTGYVTDF--APSIAP-MIPALIVHCVNEIEARGL 410
            .:|.:.||..|...|.:.|..|. .|....:.|  .||  .|...| .:|.::..|..|||.|.|
  Rat   516 EECFLTCHKRCLETLLILCGHQR-LPARMPLFG--VDFLQLPRDFPEEVPFVVTRCTAEIEHRAL 577

  Fly   411 TEVGLYRLSSSEREYKALKEQFLRGKATPHLGNTDIYVLCCCVKDFLRSLTEPLIPTSQWKDF-- 473
            ...|:||:|.|....:.|.:.|..|:|...|.....:.:...:|.||:.||:|::|...:..|
  Rat   578 GLQGIYRVSGSRVRVERLCQAFENGRALVELSGNSPHDITSVLKRFLQELTDPVVPFHFYDAFIS 642

  Fly   474 ------ANAVQNPDTKTAQDMLVKSVK----QLPQANRDTLAFLILHFQRI-AQCPVVLMPIDNI 527
                  |:...:|.|.:....:::|:|    |||.:|..||..|:.|..|: |:.....|..:|:
  Rat   643 LAKTLHADPGDDPGTPSPSPEIIRSLKTLLVQLPDSNYSTLRHLVAHLFRVAARFKENKMSANNL 707

  Fly   528 SLIFGPTIV------GYSTPDPDQHAIYTEVFTQKQVMKALL----------ELPVSFWEQYIVI 576
            .::||||::      |.::..|  .|...:...|.|:::.|:          |||::  .:.:..
  Rat   708 GIVFGPTLLRPPDGPGATSASP--VACLLDSGHQAQLVEFLIVHYEQIFGMDELPLT--SEPLTQ 768

  Fly   577 DPTRTPA 583
            ||...||
  Rat   769 DPALAPA 775

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tum	NP_610912.2	C1	319..367	CDD:237996	13/48 (27%)
		RhoGAP_MgcRacGAP	381..570	CDD:239847	60/220 (27%)
Gmip	NP_001100778.1	BAR	111..311	CDD:299863	23/102 (23%)
		C1	489..534	CDD:197519	13/47 (28%)
		RhoGAP	546..749	CDD:295372	57/206 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910